Deep learning

Enhancing human activity recognition for the elderly and individuals with disabilities through optimized Internet-of-Things and artificial intelligence integration with advanced neural networks

Thu, 2024-12-05 06:00

Front Neuroinform. 2024 Nov 19;18:1454583. doi: 10.3389/fninf.2024.1454583. eCollection 2024.

ABSTRACT

Elderly and individuals with disabilities can greatly benefit from human activity recognition (HAR) systems, which have recently advanced significantly due to the integration of the Internet of Things (IoT) and artificial intelligence (AI). The blending of IoT and AI methodologies into HAR systems has the potential to enable these populations to lead more autonomous and comfortable lives. HAR systems are equipped with various sensors, including motion capture sensors, microcontrollers, and transceivers, which supply data to assorted AI and machine learning (ML) algorithms for subsequent analyses. Despite the substantial advantages of this integration, current frameworks encounter significant challenges related to computational overhead, which arises from the complexity of AI and ML algorithms. This article introduces a novel ensemble of gated recurrent networks (GRN) and deep extreme feedforward neural networks (DEFNN), with hyperparameters optimized through the artificial water drop optimization (AWDO) algorithm. This framework leverages GRN for effective feature extraction, subsequently utilized by DEFNN for accurately classifying HAR data. Additionally, AWDO is employed within DEFNN to adjust hyperparameters, thereby mitigating computational overhead and enhancing detection efficiency. Extensive experiments were conducted to verify the proposed methodology using real-time datasets gathered from IoT testbeds, which employ NodeMCU units interfaced with Wi-Fi transceivers. The framework's efficiency was assessed using several metrics: accuracy at 99.5%, precision at 98%, recall at 97%, specificity at 98%, and F1-score of 98.2%. These results then were benchmarked against other contemporary deep learning (DL)-based HAR systems. The experimental outcomes indicate that our model achieves near-perfect accuracy, surpassing alternative learning-based HAR systems. Moreover, our model demonstrates reduced computational demands compared to preceding algorithms, suggesting that the proposed framework may offer superior efficacy and compatibility for deployment in HAR systems designed for elderly or individuals with disabilities.

PMID:39635647 | PMC:PMC11615478 | DOI:10.3389/fninf.2024.1454583

Categories: Literature Watch

Recent Progress of Cardiac MRI for Nuclear Medicine Professionals

Thu, 2024-12-05 06:00

Nucl Med Mol Imaging. 2024 Dec;58(7):431-448. doi: 10.1007/s13139-024-00850-9. Epub 2024 Feb 14.

ABSTRACT

Recent technical innovation enables faster and more reliable cardiac magnetic resonance (CMR) imaging than before. Artificial intelligence is used in improving image resolution, fast scanning, and automated analysis of CMR. Fast CMR techniques such as compressed sensing technique enable fast cine, perfusion, and late gadolinium-enhanced imaging and improve patient throughput and widening CMR indications. CMR feature-tracking technique gives insight on diastolic function parameters of ventricles and atria with prognostic implications. Myocardial parametric mapping became to be included in the routine CMR protocol. CMR fingerprinting enables simultaneous quantification of myocardial T1 and T2. These parameters may give information on myocardial alteration in the preclinical stages in various myocardial diseases. Four-dimensional flow imaging shows hemodynamic characteristics in or through the cardiovascular structures visually and gives quantitative values of vortex, kinetic energy, and wall-shear stress. In conclusion, CMR is an essential modality in the diagnosis of various cardiovascular diseases, especially myocardial diseases. Recent progress in CMR techniques promotes more widespread use of CMR in clinical practice. This review summarizes recent updates in CMR technologies and clinical research.

PMID:39635630 | PMC:PMC11612075 | DOI:10.1007/s13139-024-00850-9

Categories: Literature Watch

In-depth analysis of research hotspots and emerging trends in AI for retinal diseases over the past decade

Thu, 2024-12-05 06:00

Front Med (Lausanne). 2024 Nov 20;11:1489139. doi: 10.3389/fmed.2024.1489139. eCollection 2024.

ABSTRACT

BACKGROUND: The application of Artificial Intelligence (AI) in diagnosing retinal diseases represents a significant advancement in ophthalmological research, with the potential to reshape future practices in the field. This study explores the extensive applications and emerging research frontiers of AI in retinal diseases.

OBJECTIVE: This study aims to uncover the developments and predict future directions of AI research in retinal disease over the past decade.

METHODS: This study analyzes AI utilization in retinal disease research through articles, using citation data sourced from the Web of Science (WOS) Core Collection database, covering the period from January 1, 2014, to December 31, 2023. A combination of WOS analyzer, CiteSpace 6.2 R4, and VOSviewer 1.6.19 was used for a bibliometric analysis focusing on citation frequency, collaborations, and keyword trends from an expert perspective.

RESULTS: A total of 2,861 articles across 93 countries or regions were cataloged, with notable growth in article numbers since 2017. China leads with 926 articles, constituting 32% of the total. The United States has the highest h-index at 66, while England has the most significant network centrality at 0.24. Notably, the University of London is the leading institution with 99 articles and shares the highest h-index (25) with University College London. The National University of Singapore stands out for its central role with a score of 0.16. Research primarily spans ophthalmology and computer science, with "network," "transfer learning," and "convolutional neural networks" being prominent burst keywords from 2021 to 2023.

CONCLUSION: China leads globally in article counts, while the United States has a significant research impact. The University of London and University College London have made significant contributions to the literature. Diabetic retinopathy is the retinal disease with the highest volume of research. AI applications have focused on developing algorithms for diagnosing retinal diseases and investigating abnormal physiological features of the eye. Future research should pivot toward more advanced diagnostic systems for ophthalmic diseases.

PMID:39635592 | PMC:PMC11614663 | DOI:10.3389/fmed.2024.1489139

Categories: Literature Watch

Deep learning in light-matter interactions

Thu, 2024-12-05 06:00

Nanophotonics. 2022 Jun 14;11(14):3189-3214. doi: 10.1515/nanoph-2022-0197. eCollection 2022 Jul.

ABSTRACT

The deep-learning revolution is providing enticing new opportunities to manipulate and harness light at all scales. By building models of light-matter interactions from large experimental or simulated datasets, deep learning has already improved the design of nanophotonic devices and the acquisition and analysis of experimental data, even in situations where the underlying theory is not sufficiently established or too complex to be of practical use. Beyond these early success stories, deep learning also poses several challenges. Most importantly, deep learning works as a black box, making it difficult to understand and interpret its results and reliability, especially when training on incomplete datasets or dealing with data generated by adversarial approaches. Here, after an overview of how deep learning is currently employed in photonics, we discuss the emerging opportunities and challenges, shining light on how deep learning advances photonics.

PMID:39635557 | PMC:PMC11501725 | DOI:10.1515/nanoph-2022-0197

Categories: Literature Watch

Data enhanced iterative few-sample learning algorithm-based inverse design of 2D programmable chiral metamaterials

Thu, 2024-12-05 06:00

Nanophotonics. 2022 Sep 6;11(20):4465-4478. doi: 10.1515/nanoph-2022-0310. eCollection 2022 Sep.

ABSTRACT

A data enhanced iterative few-sample (DEIFS) algorithm is proposed to achieve the accurate and efficient inverse design of multi-shaped 2D chiral metamaterials. Specifically, three categories of 2D diffractive chiral structures with different geometrical parameters, including widths, separation spaces, bridge lengths, and gold lengths are studied utilising both the conventional rigorous coupled wave analysis (RCWA) approach and DEIFS algorithm, with the former approach assisting the training process for the latter. The DEIFS algorithm can be divided into two main stages, namely data enhancement and iterations. Firstly, some "pseudo data" are generated by a forward prediction network that can efficiently predict the circular dichroism (CD) response of 2D diffractive chiral metamaterials to reinforce the dataset after necessary denoising. Then, the algorithm uses the CD spectra and the predictions of parameters with smaller errors iteratively to achieve accurate values of the remaining parameters. Meanwhile, according to the impact of geometric parameters on the chiroptical response, a new functionality is added to interpret the experimental results of DEIFS algorithm from the perspective of data, improving the interpretability of the DEIFS. In this way, the DEIFS algorithm replaces the time-consuming iterative optimization process with a faster and simpler approach that achieves accurate inverse design with dataset whose amount is at least one to two orders of magnitude less than most previous deep learning methods, reducing the dependence on simulated spectra. Furthermore, the fast inverse design of multiple shaped metamaterials allows for different light manipulation, demonstrating excellent potentials in applications of optical coding and information processing. This work belongs to one of the first attempts to thoroughly characterize the flexibility, interpretability, and generalization ability of DEIFS algorithm in studying various chiroptical effects in metamaterials and accelerating the inverse design of hypersensitive photonic devices.

PMID:39635508 | PMC:PMC11501232 | DOI:10.1515/nanoph-2022-0310

Categories: Literature Watch

Counting and mapping of subwavelength nanoparticles from a single shot scattering pattern

Thu, 2024-12-05 06:00

Nanophotonics. 2023 Jan 18;12(14):2807-2812. doi: 10.1515/nanoph-2022-0612. eCollection 2023 Jul.

ABSTRACT

Particle counting is of critical importance for nanotechnology, environmental monitoring, pharmaceutical, food and semiconductor industries. Here we introduce a super-resolution single-shot optical method for counting and mapping positions of subwavelength particles on a surface. The method is based on the deep learning analysis of the intensity profile of the coherent light scattered on the group of particles. In a proof of principle experiment, we demonstrated particle counting accuracies of more than 90%. We also demonstrate that the particle locations can be mapped on a 4 × 4 grid with a nearly perfect accuracy (16-pixel binary imaging of the particle ensemble). Both the retrieval of number of particles and their mapping is achieved with super-resolution: accuracies are similar for sets with closely located optically unresolvable particles and sets with sparsely located particles. As the method does not require fluorescent labelling of the particles, is resilient to small variations of particle sizes, can be adopted to counting various types of nanoparticulates and high rates, it can find applications in numerous particles counting tasks in nanotechnology, life sciences and beyond.

PMID:39635469 | PMC:PMC11501414 | DOI:10.1515/nanoph-2022-0612

Categories: Literature Watch

Neural network-assisted meta-router for fiber mode and polarization demultiplexing

Thu, 2024-12-05 06:00

Nanophotonics. 2024 Sep 5;13(22):4181-4189. doi: 10.1515/nanoph-2024-0338. eCollection 2024 Sep.

ABSTRACT

Advancements in computer science have propelled society into an era of data explosion, marked by a critical need for enhanced data transmission capacity, particularly in the realm of space-division multiplexing and demultiplexing devices for fiber communications. However, recently developed mode demultiplexers primarily focus on mode divisions within one dimension rather than multiple dimensions (i.e., intensity distributions and polarization states), which significantly limits their applicability in space-division multiplexing communications. In this context, we introduce a neural network-assisted meta-router to recognize intensity distributions and polarization states of optical fiber modes, achieved through a single layer of metasurface optimized via neural network techniques. Specifically, a four-mode meta-router is theoretically designed and experimentally characterized, which enables four modes, comprising two spatial modes with two polarization states, independently divided into distinct spatial regions, and successfully recognized by positions of corresponding spatial regions. Our framework provides a paradigm for fiber mode demultiplexing apparatus characterized by application compatibility, transmission capacity, and function scalability with ultra-simple design and ultra-compact device. Merging metasurfaces, neural network and mode routing, this proposed framework paves a practical pathway towards intelligent metasurface-aided optical interconnection, including applications such as fiber communication, object recognition and classification, as well as information display, processing, and encryption.

PMID:39635450 | PMC:PMC11501066 | DOI:10.1515/nanoph-2024-0338

Categories: Literature Watch

Leveraging deep transfer learning and explainable AI for accurate COVID-19 diagnosis: Insights from a multi-national chest CT scan study

Wed, 2024-12-04 06:00

Comput Biol Med. 2024 Dec 3;185:109461. doi: 10.1016/j.compbiomed.2024.109461. Online ahead of print.

ABSTRACT

The COVID-19 pandemic has emerged as a global health crisis, impacting millions worldwide. Although chest computed tomography (CT) scan images are pivotal in diagnosing COVID-19, their manual interpretation by radiologists is time-consuming and potentially subjective. Automated computer-aided diagnostic (CAD) frameworks offer efficient and objective solutions. However, machine or deep learning methods often face challenges in their reproducibility due to underlying biases and methodological flaws. To address these issues, we propose XCT-COVID, an explainable, transferable, and reproducible CAD framework based on deep transfer learning to predict COVID-19 infection from CT scan images accurately. This is the first study to develop three distinct models within a unified framework by leveraging a previously unexplored large dataset and two widely used smaller datasets. We employed five known convolutional neural network architectures, both with and without pretrained weights, on the larger dataset. We optimized hyperparameters through extensive grid search and 5-fold cross-validation (CV), significantly enhancing the model performance. Experimental results from the larger dataset showed that the VGG16 architecture (XCT-COVID-L) with pretrained weights consistently outperformed other architectures, achieving the best performance, on both 5-fold CV and independent test. When evaluated with the external datasets, XCT-COVID-L performed well with data with similar distributions, demonstrating its transferability. However, its performance significantly decreased on smaller datasets with lower-quality images. To address this, we developed other models, XCT-COVID-S1 and XCT-COVID-S2, specifically for the smaller datasets, outperforming existing methods. Moreover, eXplainable Artificial Intelligence (XAI) analyses were employed to interpret the models' functionalities. For prediction and reproducibility purposes, the implementation of XCT-COVID is publicly accessible at https://github.com/cbbl-skku-org/XCT-COVID/.

PMID:39631112 | DOI:10.1016/j.compbiomed.2024.109461

Categories: Literature Watch

A smart CardioSenseNet framework with advanced data processing models for precise heart disease detection

Wed, 2024-12-04 06:00

Comput Biol Med. 2024 Dec 3;185:109473. doi: 10.1016/j.compbiomed.2024.109473. Online ahead of print.

ABSTRACT

Heart diseases remain one of the leading causes of death worldwide. As a result, early and accurate diagnostics have become an urgent need for treatment and management. Most of the conventional methods adopted tend to have major drawbacks: the issues of accuracy, interpretability, and feature representation. This work, therefore, proposes CardioSenseNet, which may provide a new framework that can improve accuracy and efficiency in heart disease detection. Firstly, the approach introduces a few new methods: DGPN for data preprocessing, STHIO for feature selection, and SADNet for prediction. DGPN normalizes the data depending on the distribution characteristic, which improves the quality of the feature representation. STHIO adopts the Sheep Flock Optimization method for the exploration of features and Tuna Swarm Optimization for the exploitation of features, guaranteeing the optimality in feature selection. SADNet is one such deep learning model that tries to find the complicated pattern in high-dimensional data for better prediction accuracy. Extensive experiments on benchmark datasets such as Cleveland and CVD endorse the efficiency of CardioSenseNet with a high accuracy of 99 % and at an minimum loss of 0.12 %. The results thus indicate that CardioSenseNet is a promising solution for the detection of heart diseases with high accuracy and at an early stage; therefore, it will contribute significantly to cardiovascular healthcare developments.

PMID:39631110 | DOI:10.1016/j.compbiomed.2024.109473

Categories: Literature Watch

A review of convolutional neural network based methods for medical image classification

Wed, 2024-12-04 06:00

Comput Biol Med. 2024 Dec 3;185:109507. doi: 10.1016/j.compbiomed.2024.109507. Online ahead of print.

ABSTRACT

This study systematically reviews CNN-based medical image classification methods. We surveyed 149 of the latest and most important papers published to date and conducted an in-depth analysis of the methods used therein. Based on the selected literature, we organized this review systematically. First, the development and evolution of CNN in the field of medical image classification are analyzed. Subsequently, we provide an in-depth overview of the main techniques of CNN applied to medical image classification, which is also the current research focus in this field, including data preprocessing, transfer learning, CNN architectures, and explainability, and their role in improving classification accuracy and efficiency. In addition, this overview summarizes the main public datasets for various diseases. Although CNN has great potential in medical image classification tasks and has achieved good results, clinical application is still difficult. Therefore, we conclude by discussing the main challenges faced by CNNs in medical image analysis and pointing out future research directions to address these challenges. This review will help researchers with their future studies and can promote the successful integration of deep learning into clinical practice and smart medical systems.

PMID:39631108 | DOI:10.1016/j.compbiomed.2024.109507

Categories: Literature Watch

Physics-guided deep learning for skillful wind-wave modeling

Wed, 2024-12-04 06:00

Sci Adv. 2024 Dec 6;10(49):eadr3559. doi: 10.1126/sciadv.adr3559. Epub 2024 Dec 4.

ABSTRACT

Modeling sea surface wind-waves is crucial for both scientific research and engineering applications. Nowadays, the most accurate wave models are based on numerical methods, which primarily concern the wave spectrum evolution by solving wave action balance partial differential equations. These methods are computationally expensive and limited by incomplete physical representations of wave spectral evolution. Here, we present a deep learning-based wave model trained using observation-merged wave hindcasts. Guided by the physics knowledge that waves are either generated by local current winds or by remote historical winds, this method can directly model significant wave height, bypassing the need for wave spectral information. This feature engineering effectively reduces the complexity of model inputs and outputs. The resulting artificial intelligence method can model 1 year of global significant wave heights at a 0.5° × 0.5° × 1-hour resolution within half an hour on a personal computer, achieving higher accuracy than state-of-the-art numerical wave models.

PMID:39630901 | DOI:10.1126/sciadv.adr3559

Categories: Literature Watch

Sunflower-like self-sustainable plant-wearable sensing probe

Wed, 2024-12-04 06:00

Sci Adv. 2024 Dec 6;10(49):eads1136. doi: 10.1126/sciadv.ads1136. Epub 2024 Dec 4.

ABSTRACT

Powering and communicating with wearable devices on bio-interfaces is challenging due to strict weight, size, and resource constraints. This study presents a sunflower-like plant-wearable sensing device that harnesses solar energy, achieving complete energy self-sustainability for long-term monitoring of plant sap flow, a crucial indicator of plant health. It features foldable solar panels along with all essential flexible electronic components, resulting in a compact system that is lightweight enough for small plants. To tackle the low-energy density of solar power, we developed an ultralow-energy light communication mechanism inspired by fireflies. Together with unmanned aerial vehicles and deep learning algorithms, this approach enables efficient data retrieval from multiple devices across large agricultural fields. With its simple deployment, it shows great potential as a low-cost plant phenotyping tool. We believe our energy and communication solution for wearable devices can be extended to similar resource-limited and challenging scenarios, leading to exciting applications.

PMID:39630896 | DOI:10.1126/sciadv.ads1136

Categories: Literature Watch

Deep learning analysis of fMRI data for predicting Alzheimer's Disease: A focus on convolutional neural networks and model interpretability

Wed, 2024-12-04 06:00

PLoS One. 2024 Dec 4;19(12):e0312848. doi: 10.1371/journal.pone.0312848. eCollection 2024.

ABSTRACT

The early detection of Alzheimer's Disease (AD) is thought to be important for effective intervention and management. Here, we explore deep learning methods for the early detection of AD. We consider both genetic risk factors and functional magnetic resonance imaging (fMRI) data. However, we found that the genetic factors do not notably enhance the AD prediction by imaging. Thus, we focus on building an effective imaging-only model. In particular, we utilize data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), employing a 3D Convolutional Neural Network (CNN) to analyze fMRI scans. Despite the limitations posed by our dataset (small size and imbalanced nature), our CNN model demonstrates accuracy levels reaching 92.8% and an ROC of 0.95. Our research highlights the complexities inherent in integrating multimodal medical datasets. It also demonstrates the potential of deep learning in medical imaging for AD prediction.

PMID:39630834 | DOI:10.1371/journal.pone.0312848

Categories: Literature Watch

Multiscale effective connectivity analysis of brain activity using neural ordinary differential equations

Wed, 2024-12-04 06:00

PLoS One. 2024 Dec 4;19(12):e0314268. doi: 10.1371/journal.pone.0314268. eCollection 2024.

ABSTRACT

Neural mechanisms and underlying directionality of signaling among brain regions depend on neural dynamics spanning multiple spatiotemporal scales of population activity. Despite recent advances in multimodal measurements of brain activity, there is no broadly accepted multiscale dynamical models for the collective activity represented in neural signals. Here we introduce a neurobiological-driven deep learning model, termed multiscale neural dynamics neural ordinary differential equation (msDyNODE), to describe multiscale brain communications governing cognition and behavior. We demonstrate that msDyNODE successfully captures multiscale activity using both simulations and electrophysiological experiments. The msDyNODE-derived causal interactions between recording locations and scales not only aligned well with the abstraction of the hierarchical neuroanatomy of the mammalian central nervous system but also exhibited behavioral dependences. This work offers a new approach for mechanistic multiscale studies of neural processes.

PMID:39630698 | DOI:10.1371/journal.pone.0314268

Categories: Literature Watch

Predicting progression-free survival in sarcoma using MRI-based automatic segmentation models and radiomics nomograms: a preliminary multicenter study

Wed, 2024-12-04 06:00

Skeletal Radiol. 2024 Dec 4. doi: 10.1007/s00256-024-04837-7. Online ahead of print.

ABSTRACT

OBJECTIVES: Some sarcomas are highly malignant, associated with high recurrence despite treatment. This multicenter study aimed to develop and validate a radiomics signature to estimate sarcoma progression-free survival (PFS).

MATERIALS AND METHODS: The study retrospectively enrolled 202 consecutive patients with pathologically diagnosed sarcoma, who had pre-treatment axial fat-suppressed T2-weighted images (FS-T2WI), and included them in the ROI-Net model for training. Among them, 120 patients were included in the radiomics analysis, all of whom had pre-treatment axial T1-weighted and transverse FS-T2WI images, and were randomly divided into a development group (n = 96) and a validation group (n = 24). In the development cohort, Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression was used to develop the radiomics features for PFS prediction. By combining significant clinical features with radiomics features, a nomogram was constructed using Cox regression.

RESULTS: The proposed ROI-Net framework achieved a Dice coefficient of 0.820 (0.791-0.848). The radiomics signature based on 21 features could distinguish high-risk patients with poor PFS. Univariate Cox analysis revealed that peritumoral edema, metastases, and the radiomics score were associated with poor PFS and were included in the construction of the nomogram. The Radiomics-T1WI-Clinical model exhibited the best performance, with AUC values of 0.947, 0.907, and 0.924 at 300 days, 600 days, and 900 days, respectively.

CONCLUSION: The proposed ROI-Net framework demonstrated high consistency between its segmentation results and expert annotations. The radiomics features and the combined nomogram have the potential to aid in predicting PFS for patients with sarcoma.

PMID:39630238 | DOI:10.1007/s00256-024-04837-7

Categories: Literature Watch

Correction to: Deep learning-based reconstruction improves the image quality of low-dose CT enterography in patients with inflammatory bowel disease

Wed, 2024-12-04 06:00

Abdom Radiol (NY). 2024 Dec 4. doi: 10.1007/s00261-024-04694-x. Online ahead of print.

NO ABSTRACT

PMID:39630201 | DOI:10.1007/s00261-024-04694-x

Categories: Literature Watch

Automatic Quantitative Analysis of Internal Quantum Efficiency Measurements of GaAs Solar Cells Using Deep Learning

Wed, 2024-12-04 06:00

Adv Sci (Weinh). 2024 Dec 4:e2407048. doi: 10.1002/advs.202407048. Online ahead of print.

ABSTRACT

A solar cell's internal quantum efficiency (IQE) measurement reveals critical information about the device's performance. This information can be obtained using a qualitative analysis of the shape of the curve, identifying and attributing current losses such as at the front and rear interfaces, and extracting key electrical and optical performance parameters. However, conventional methods to extract the performance parameters from IQE measurements are often time-consuming and require manual fitting approaches. While several methodologies exist to extract those parameters from silicon solar cells, there is a lack of accessible approaches for non-silicon cell technologies, like gallium arsenide cells, typically limiting the analysis to only the qualitative level. Therefore, this study proposes using a deep learning method to automatically predict multiple key parameters from IQE measurements of gallium arsenide cells. The proposed method is demonstrated to achieve a very high level of prediction accuracy across the entire range of parameter values and exhibits a high resilience for noisy measurements. By enhancing the quantitative analysis of IQE measurements, the method will unlock the full potential of quantum efficiency measurements as a powerful characterization tool for diverse solar cell technologies.

PMID:39630124 | DOI:10.1002/advs.202407048

Categories: Literature Watch

Automated Segmentation of Fetal Intracranial Volume in Three-Dimensional Ultrasound Using Deep Learning: Identifying Sex Differences in Prenatal Brain Development

Wed, 2024-12-04 06:00

Hum Brain Mapp. 2024 Dec 1;45(17):e70058. doi: 10.1002/hbm.70058.

ABSTRACT

The human brain undergoes major developmental changes during pregnancy. Three-dimensional (3D) ultrasound images allow for the opportunity to investigate typical prenatal brain development on a large scale. Transabdominal ultrasound can be challenging due to the small fetal brain and its movement, as well as multiple sweeps that may not yield high-quality images, especially when brain structures are unclear. By applying the latest developments in artificial intelligence for automated image processing allowing automated training of brain anatomy in these images retrieving reliable quantitative brain measurements becomes possible at a large scale. Here, we developed a convolutional neural network (CNN) model for automated segmentation of fetal intracranial volume (ICV) from 3D ultrasound. We applied the trained model in a large longitudinal population sample from the YOUth Baby and Child cohort measured at 20- and 30-week of gestational age to investigate biological sex differences in fetal ICV as a proof-of-principle and validation for our automated method (N = 2235 individuals with 43492 ultrasounds). A total of 168 annotated, randomly selected, good quality 3D ultrasound whole-brain images were included to train a 3D CNN for automated fetal ICV segmentation. A data augmentation strategy provided physical variation to train the network. K-fold cross-validation and Bayesian optimization were used for network selection and the ensemble-based system combined multiple networks to form the final ensemble network. The final ensemble network produced consistent and high-quality segmentations of ICV (Dice Similarity Coefficient (DSC) > 0.93, Hausdorff Distance (HD): HDvoxel < 4.6 voxels, and HDphysical < 1.4 mm). In addition, we developed an automated quality control procedure to include the ultrasound scans that successfully predicted ICV from all 43492 3D ultrasounds available in all individuals, no longer requiring manual selection of the best scan for analysis. Our trained model automatically retrieved ultrasounds with brain data and estimated ICV and ICV growth in 7672 (18%) of ultrasounds in 1762 participants that passed the automatic quality control procedure. Boys had significantly larger ICV at 20-weeks (81.7 ± 0.4 mL vs. 80.8 ± 0.5 mL; B = 2.86; p = 5.7e-14) and 30-weeks (257.0 ± 0.9 mL vs. 245.1 ± 0.9 mL; B = 12.35; p = 8.2e-27) of pregnancy, and more pronounced ICV growth than girls (delta growth 0.12 mL/day; p = 1.8e-5). Our automated artificial intelligence approach provides an opportunity to investigate fetal brain development on a much larger scale and to answer fundamental questions related to prenatal brain development.

PMID:39629904 | DOI:10.1002/hbm.70058

Categories: Literature Watch

A Deep Learning Based Framework to Identify Undocumented Orphaned Oil and Gas Wells from Historical Maps: A Case Study for California and Oklahoma

Wed, 2024-12-04 06:00

Environ Sci Technol. 2024 Dec 4. doi: 10.1021/acs.est.4c04413. Online ahead of print.

ABSTRACT

Undocumented Orphaned Wells (UOWs) are wells without an operator that have limited or no documentation with regulatory authorities. An estimated 310,000 to 800,000 UOWs exist in the United States (US), whose locations are largely unknown. These wells can potentially leak methane and other volatile organic compounds to the atmosphere, and contaminate groundwater. In this study, we developed a novel framework utilizing a state-of-the-art computer vision neural network model to identify the precise locations of potential UOWs. The U-Net model is trained to detect oil and gas well symbols in georeferenced historical topographic maps, and potential UOWs are identified as symbols that are further than 100 m from any documented well. A custom tool was developed to rapidly validate the potential UOW locations. We applied this framework to four counties in California and Oklahoma, leading to the discovery of 1301 potential UOWs across >40,000 km2. We confirmed the presence of 29 UOWs from satellite images and 15 UOWs from magnetic surveys in the field with a spatial accuracy on the order of 10 m. This framework can be scaled to identify potential UOWs across the US since the historical maps are available for the entire nation.

PMID:39629830 | DOI:10.1021/acs.est.4c04413

Categories: Literature Watch

Prediction of Brain Cancer Occurrence and Risk Assessment of Brain Hemorrhage Using Hybrid Deep Learning Technique

Wed, 2024-12-04 06:00

Cancer Invest. 2024 Dec 4:1-23. doi: 10.1080/07357907.2024.2431829. Online ahead of print.

ABSTRACT

The prediction of brain cancer occurrence and risk assessment of brain hemorrhage using a hybrid deep learning (DL) technique is a critical area of research in medical imaging analysis. One prominent challenge in this field is the accurate identification and classification of brain tumors and hemorrhages, which can significantly impact patient prognosis and treatment planning. The objectives of the study address the prediction of brain cancer occurrence and the assessment of risk levels associated with both brain cancers due to brain hemorrhage. A diverse dataset of brain MRI and CT scan images. Utilize Unsymmetrical Trimmed Median Filter with Optics Clustering for noise removal while preserving edges and details. The Chan-Vese segmentation process for refined segmentation. Brain cancer detection using Multi-Head Self-Attention Dilated Convolution Neural Network (MH-SA-DCNN) with Efficient Net Model. Brain cancer detection using MH-SA-DCNN with Efficient Net Model. This trains the algorithm to predict cancerous regions in brain images. Further, implement a Graph-Based Deep Neural Network Model (G-DNN) to capture spatial relationships and risk factors from brain images. Cox regression model to estimate cancer risk over time and fine-tune and optimize the model's parameters and features using the Osprey optimization algorithm (OPA).

PMID:39629783 | DOI:10.1080/07357907.2024.2431829

Categories: Literature Watch

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