Funding Opportunity PAR-24-148 from the NIH Guide for Grants and Contracts. This FOA would support establishing deeper mechanistic insight and causal relationships between TDP-43 pathology and phenotypic outcomes, as well as mechanistic interactions between TDP-43 and other co-pathologies, such TMEM106B. Additionally, it would include comparisons (including mechanistic, molecular, structural, cellular, genetic, -omic, anatomical, neuropathological, etc.) between TDP-43 proteinopathies, including LATE, with or without AD-NC, and FTD and/or ALS.

Funding Opportunity PAR-24-147 from the NIH Guide for Grants and Contracts. This NOFO would support investigations with a minimum of two relevant co-pathologies (e.g., tau, alpha-synuclein, TDP-43, TMEM106B, vascular), with optional risk factors and co-morbidities, to identify cellular and molecular mechanisms of how/why multi-proteinopathy interactions drive worsening neurodegenerative processes and phenotypic outcomes. Studies should examine co-pathology cellular and molecular interactions across brain regions and time in proximate cell population, across various intracellular dynamics and localization, and upstream and downstream from aggregated protein states to determine what events lead to worse phenotypic outcomes.

Funding Opportunity RFA-AG-25-016 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to invite applications proposing to establish multi-scale computational models recapitulating dynamic changes associated with aging and Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD). This broad scope encompasses a variety of computational approachessuch as mathematical and computational modeling, image analysis, artificial intelligence, and machine learningto better understand aging processes and AD/ADRD across molecules, cells and networks, and cognition and behavior.

Notice NOT-AI-24-015 from the NIH Guide for Grants and Contracts

Notice NOT-AR-24-012 from the NIH Guide for Grants and Contracts

Notice NOT-DA-23-064 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-055 from the NIH Guide for Grants and Contracts

Notice NOT-AT-24-027 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-029 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-056 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-057 from the NIH Guide for Grants and Contracts

F. Hoffmann-La Roche AG: 2024 Summer Intern - System Development Department Department Summary Our System Development team is committed to evaluating and integrating system... Santa Clara, California, United States of America

AbbVie: AbbVie's Genomic Research Center (GRC) is seeking a highly qualified bioinformatics scientist to join the Emerging Technology (ET) Group within the... North Chicago, Illinois

Element Biosciences: At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our... San Diego, California

St. Jude Children's Research Hospital: We are seeking a talented, highly motivated Senior Bioinformatics Research Scientist to lead our bioinformatics pipeline and develop innovative sol... Memphis, Tennessee

Leidos: Are you looking for a career that will make an impact? The Leidos Health & Civil Sector is currently looking for a Bioinformatics Engineer to suppo... Frederick, Maryland

Notice NOT-OD-24-059 from the NIH Guide for Grants and Contracts

Notice NOT-MH-24-170 from the NIH Guide for Grants and Contracts

Grade 6/7, £32,332 - £36,024/£39,347 - £44,263 per annum : University of Glasgow: We are looking to recruit a Research Assistant/Associate to join the School of Infection and Immunity, MRC-UoG Centre for Virus Research (CVR) Glasgow, Glasgow City

Notice NOT-AT-24-033 from the NIH Guide for Grants and Contracts