Funding Opportunity PAR-25-268 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.

Funding Opportunity PAR-24-290 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NEI R25 program is to support educational activities that complement and/or enhance the training of a diverse workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on Research Experiences The NEI supports basic, translational, and clinical research on vision and diseases of the visual system as detailed in the NEI Strategic Plan. The purpose of this funding opportunity is to encourage applications for research education programs that will significantly advance the mission of NEI. The proposed research education programs should focus on intensive hands-on research experiences to prepare recent college graduates from diverse backgrounds for biomedical doctoral degree programs. In addition to encouraging individuals from diverse backgrounds to pursue careers in biomedical research, NEI also seeks to recruit individuals without prior opportunities to participate in research in the visual sciences. Programs appropriate for this NOFO must include participants from a nationally recruited cohort. This NOFO does not allow appointed participants to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Funding Opportunity PAR-25-267 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite feasibility trials is expected to be justified by sufficient preliminary data from previous single site feasibility or acceptability trial(s) or the published literature. The data collected should be used to fill gaps in scientific knowledge and be necessary to develop a competitive fully powered multisite clinical trial that has the potential to make a significant impact on public health.

Funding Opportunity RFA-NS-25-027 from the NIH Guide for Grants and Contracts. This announcement provides support to eligible, domestic institutions to develop and implement effective, approaches to biomedical research education and mentoring that will keep pace with the rapid evolution of the research enterprise. This NIH Neuroscience Doctoral Readiness Program (DR Program) expects that the proposed research education programs will incorporate extensive research experiences within the NINDS mission and well-designed courses for skills development and education to prepare recent baccalaureates from diverse backgrounds to transition into and complete rigorous, research-focused doctoral degree programs (e.g., Ph.D. or M.D./Ph.D.) in biomedical fields. This is a limited competition funding opportunity announcement to support postbaccalaureate programs that will be affiliated with a funded NIH T32 program. Eligibility is limited to PD(s)/PI(s) or MPI teams that include at least one PD/PI of a grant supported by the following FOAs: T32 - Jointly Sponsored Institutional Predoctoral Training Program (JSPTPN), PAR-20-076;NINDS T32 - Institutional Research Training Grant, PAR-21-149; or NINDS T32 - Institutional Translational Research Training Program, PAR-19-228. In all cases, a PD/PI of the T32 grant from a FOA cited above, must be the PD/PI or an MPI of this R25. This Funding Opportunity Announcement (FOA) does not allow appointed participants to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Competitive: Insmed EU Careers: Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare disease Cambridgeshire, United Kingdom

Competitive: Unreal Gigs: Are you passionate about using science to create breakthroughs in biotechnology that can revolutionize medicine, agriculture, and environmental sustai London, United Kingdom

Competitive: Cardiff University: Advert Research Associate in Bioinformatics and Machine Learning Division of Psychological Medicine and Clinical Neurosciences School of Medicine Col United Kingdom

Competitive: Medical Research Council: View Vacancy -- MRC Investigator Scientist in Bioinformatics and Genetics LMS 2509 Open Date 28/10/2024, 10:00 Close Date 20/11/2024, 23:55 R London, United Kingdom

Competitive: Insmed EU Careers: Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare disease Cambridgeshire, United Kingdom

Competitive: Unreal Gigs: Are you passionate about turning complex biological data into meaningful insights that drive breakthroughs in health, medicine, and biotechnology? Do London, United Kingdom

Competitive: Unreal Gigs: Are you passionate about turning complex biological data into meaningful insights that drive breakthroughs in health, medicine, and biotechnology? Do Cambridge, United Kingdom

Competitive: Intertek: Job Description ABOUT YOU As a Senior Scientist you will work as a senior member of the Laboratory with accountability for leading, managing and d Lancashire, United Kingdom

Notice NOT-AI-24-072 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-25-217 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) Tackling Acquisition of Language in Kids (TALK) initiative seeks to support activities to better understand early language learning and delay. NIH TALK invites applications for research projects that aim to better understand the information and practice needs of caregivers, professionals, and other invested parties who support late talking children and to determine whether those needs are being effectively met. Community engaged research combined with rigorous qualitative research and diverse perspectives is needed to enrich our understanding of how to get state-of-the-science information and practice to those who need it most to guide decisions about late talking children.

Funding Opportunity PAR-25-220 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support research projects that aim to further understanding of the developmental trajectories of late talking children by leveraging existing data and creating open and shared data resources to aid in identifying patterns and predictors of developmental outcomes in late talking children, and exploring potential underlying mechanisms, risk factors, and sequalae.

Funding Opportunity RFA-DA-26-034 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations (fentanyl and xylazine). This NOFO will also support research on the persistent and/or delayed pathophysiological effects after acute exposure to such agents.

Negotiable: Oxford Nanopore Technologies: Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many Netherlands

Funding Opportunity RFA-OH-25-003 from the NIH Guide for Grants and Contracts. The purpose of this announcement is to invite grant applications for Training Project Grants that are focused on occupational safety and health training.

Notice NOT-AI-24-078 from the NIH Guide for Grants and Contracts

Notice NOT-AI-25-001 from the NIH Guide for Grants and Contracts