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Nonhuman Primate Transplantation Tolerance Cooperative Study Group (U01 Clinical Trial Not Allowed)

Funding Opportunity RFA-AI-22-002 from the NIH Guide for Grants and Contracts. This purpose of this RFA is to solicit applications for the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG), a multi-center, cooperative program dedicated to developing, optimizing, and evaluating approaches to induce and maintain immune tolerance to allogeneic transplants in nonhuman primate (NHP) models. The over-arching goal is to facilitate clinical translation of safe and effective tolerance-induction protocols for long-term graft survival.

Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes: Assay and Data Generation Centers (RM1 Clinical Trial Not Allowed)

Funding Opportunity RFA-MH-22-111 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports systematic and scalable approaches to profile the biological function of genes with an excess of damaging mutations in patients with neurodevelopmental and psychiatric disorders. Current understanding of the relationship between genetic and phenotypic variation is limited and one of the main bottlenecks in translating disease-associated genes to biology lies in the lack of scalable experimental platforms that can extend the unbiased nature of gene discovery to the discovery of biological mechanisms. This concept will attempt to fill that gap while also providing a bridge between existing NIMH efforts such as PsychENCODE and Convergent Neuroscience. New technologies and approaches are now making it possible to systematically implement high-throughput assays to determine how disease-linked genetic variation impacts neural function across biological levels of organization. This initiative proposes a series of FOAs to support the large-scale implementation of high-throughput assays to interrogate the molecular, cellular and physiological function of hundreds of disease-associated genes in parallel. A combination of full-scale and pilot projects will form a consortium for broad characterization of risk genes across an array of endpoints relevant to CNS function using a variety of experimental platforms (e.g., cellular, organismal). A consortium coordination center (CCC) will serve as a central hub providing administrative coordination across projects, including data and tools harmonization, development of an open-source portal to create a unified dataset and creating a standardized set of biological resources for use by the research community.

Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes: Data Resource and Administrative Coordination Center (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-MH-22-110 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports systematic and scalable approaches to profile the biological function of genes with an excess of damaging mutations in patients with neurodevelopmental and psychiatric disorders. Current understanding of the relationship between genetic and phenotypic variation is limited and one of the main bottlenecks in translating disease-associated genes to biology lies in the lack of scalable experimental platforms that can extend the unbiased nature of gene discovery to the discovery of biological mechanisms. This concept will attempt to fill that gap while also providing a bridge between existing NIMH efforts such as PsychENCODE and Convergent Neuroscience. New technologies and approaches are now making it possible to systematically implement high-throughput assays to determine how disease-linked genetic variation impacts neural function across biological levels of organization. This initiative proposes a series of FOAs to support the large-scale implementation of high-throughput assays to interrogate the molecular, cellular and physiological function of hundreds of disease-associated genes in parallel. A combination of full-scale and pilot projects will form a consortium for broad characterization of risk genes across an array of endpoints relevant to CNS function using a variety of experimental platforms (e.g., cellular, organismal). A consortium coordination center (CCC) will serve as a central hub providing administrative coordination across projects, including data and tools harmonization, development of an open-source portal to create a unified dataset and creating a standardized set of biological resources for use by the research community.

CK Group: Cell Biologist

New Scientist - Bioinformatics - Mon, 2022-01-17 19:00
Up to £35.58 per hour Umb: CK Group: CK Group are recruiting for a Senior Cell Biologist to join a company in the healthcare industry at their site based in Stevenage initially on... Stevenage
Categories: Job Watch

Bioinformatics Analyst I in the Division of Biostatistics - Medical College of Wisconsin - Milwaukee, WI

Indeed.com - Bioinformatics - Mon, 2022-01-17 16:10
Bioinformatics Analyst I in the Division of Biostatistics Purpose Under general supervision, assists in the development, maintenance and testing of genomic…
From Medical College of Wisconsin - Mon, 17 Jan 2022 21:10:29 GMT - View all Milwaukee, WI jobs
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USDA-ARS Postdoctoral Fellowship in Dairy and Animal Sciences - U.S. Department of Agriculture (USDA) - Madison, WI

Indeed.com - Bioinformatics - Fri, 2022-01-14 15:12
Work experience in bioinformatics analysis using sequencing data, e.g., genomics and transcriptomics sequencing data. U.S. Department of Agriculture (USDA).
From Oak Ridge Associated Universities - Fri, 14 Jan 2022 20:12:24 GMT - View all Madison, WI jobs
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