Job Watch

Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes: Assay and Data Generation Centers (RM1 Clinical Trial Not Allowed)

Funding Opportunity RFA-MH-22-111 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports systematic and scalable approaches to profile the biological function of genes with an excess of damaging mutations in patients with neurodevelopmental and psychiatric disorders. Current understanding of the relationship between genetic and phenotypic variation is limited and one of the main bottlenecks in translating disease-associated genes to biology lies in the lack of scalable experimental platforms that can extend the unbiased nature of gene discovery to the discovery of biological mechanisms. This concept will attempt to fill that gap while also providing a bridge between existing NIMH efforts such as PsychENCODE and Convergent Neuroscience. New technologies and approaches are now making it possible to systematically implement high-throughput assays to determine how disease-linked genetic variation impacts neural function across biological levels of organization. This initiative proposes a series of FOAs to support the large-scale implementation of high-throughput assays to interrogate the molecular, cellular and physiological function of hundreds of disease-associated genes in parallel. A combination of full-scale and pilot projects will form a consortium for broad characterization of risk genes across an array of endpoints relevant to CNS function using a variety of experimental platforms (e.g., cellular, organismal). A consortium coordination center (CCC) will serve as a central hub providing administrative coordination across projects, including data and tools harmonization, development of an open-source portal to create a unified dataset and creating a standardized set of biological resources for use by the research community.

Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes: Data Resource and Administrative Coordination Center (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-MH-22-110 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports systematic and scalable approaches to profile the biological function of genes with an excess of damaging mutations in patients with neurodevelopmental and psychiatric disorders. Current understanding of the relationship between genetic and phenotypic variation is limited and one of the main bottlenecks in translating disease-associated genes to biology lies in the lack of scalable experimental platforms that can extend the unbiased nature of gene discovery to the discovery of biological mechanisms. This concept will attempt to fill that gap while also providing a bridge between existing NIMH efforts such as PsychENCODE and Convergent Neuroscience. New technologies and approaches are now making it possible to systematically implement high-throughput assays to determine how disease-linked genetic variation impacts neural function across biological levels of organization. This initiative proposes a series of FOAs to support the large-scale implementation of high-throughput assays to interrogate the molecular, cellular and physiological function of hundreds of disease-associated genes in parallel. A combination of full-scale and pilot projects will form a consortium for broad characterization of risk genes across an array of endpoints relevant to CNS function using a variety of experimental platforms (e.g., cellular, organismal). A consortium coordination center (CCC) will serve as a central hub providing administrative coordination across projects, including data and tools harmonization, development of an open-source portal to create a unified dataset and creating a standardized set of biological resources for use by the research community.

CK Group: Cell Biologist

New Scientist - Bioinformatics - Mon, 2022-01-17 19:00
Up to £35.58 per hour Umb: CK Group: CK Group are recruiting for a Senior Cell Biologist to join a company in the healthcare industry at their site based in Stevenage initially on... Stevenage
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Bioinformatics Analyst I in the Division of Biostatistics - Medical College of Wisconsin - Milwaukee, WI

Indeed.com - Bioinformatics - Mon, 2022-01-17 16:10
Bioinformatics Analyst I in the Division of Biostatistics Purpose Under general supervision, assists in the development, maintenance and testing of genomic…
From Medical College of Wisconsin - Mon, 17 Jan 2022 21:10:29 GMT - View all Milwaukee, WI jobs
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USDA-ARS Postdoctoral Fellowship in Dairy and Animal Sciences - U.S. Department of Agriculture (USDA) - Madison, WI

Indeed.com - Bioinformatics - Fri, 2022-01-14 15:12
Work experience in bioinformatics analysis using sequencing data, e.g., genomics and transcriptomics sequencing data. U.S. Department of Agriculture (USDA).
From Oak Ridge Associated Universities - Fri, 14 Jan 2022 20:12:24 GMT - View all Madison, WI jobs
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EMBL: Senior Programme Manager - EMBL-EBI Services

New Scientist - Bioinformatics - Fri, 2022-01-14 10:37
Competitive Salary: EMBL: EMBL's European Bioinformatics Institute (EMBL-EBI) is seeking a Senior Programme Manager to lead strategic initiatives and projects to support the ef Hinxton, Cambridgeshire, England
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Robert Koch-Instiut: Centre for Artificial Intelligence in Public Health Research

New Scientist - Bioinformatics - Thu, 2022-01-13 05:19
Competitve Salary: Robert Koch-Instiut: The new “Centre for Artificial Intelligence in Public Health Research” (ZKI-PH) offers a unique working.... Wildau, Brandenburg (DE)
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Wellcome Sanger Institute: Head of Analysis Ready Data

New Scientist - Bioinformatics - Wed, 2022-01-12 18:36
£74,891 - £88,000: Wellcome Sanger Institute: We are looking for a Head of Analysis Ready Data (Senior Bioinformatician) who is passionate about working alongside partners around the globe to b... Cambridgeshire (GB)
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Wellcome Sanger Institute: Principal Bioinformatician

New Scientist - Bioinformatics - Wed, 2022-01-12 18:33
£46,199 - £54,000: Wellcome Sanger Institute: We are recruiting a Principal Bioinformatician for Pathogen Informatics, a software development and bioinformatics support team in the Parasites an... Cambridge, Cambridgeshire (GB)
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Laboratory Supervisor - State of Wyoming - Cheyenne, WY

Indeed.com - Bioinformatics - Wed, 2022-01-12 15:56
Description and Functions Open Until Filled GENERAL DESCRIPTION: This position will supervise the Molecular and Emerging Infectious Diseases sections of… $5,289 - $6,815 a month
From State of Wyoming - Wed, 12 Jan 2022 20:56:16 GMT - View all Cheyenne, WY jobs
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Wellcome Sanger Institute: Staff scientist - Glioblastoma Spatial Multi-omics

New Scientist - Bioinformatics - Wed, 2022-01-12 08:33
£37,865-£45,359 per annum + benefits: Wellcome Sanger Institute: The opportunity: The Bayraktar group is seeking a staff scientist to explore how the tumour microenvironment (TME) drives malignant cell states in ... Cambridgeshire (GB)
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Wellcome Sanger Institute: Postdoctoral Fellow in GBM Spatial Multi-omics

New Scientist - Bioinformatics - Wed, 2022-01-12 07:08
£32,780-£41,093 per annum + benefits: Wellcome Sanger Institute: The opportunity: The Bayraktar group is seeking a postdoctoral fellow to explore how the tumour microenvironment (TME) drives malignant cell states... Cambridgeshire
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Wellcome Sanger Institute: Senior Bioinformatician - Cancer Drug Combinations

New Scientist - Bioinformatics - Wed, 2022-01-12 04:31
£38,433-£46,039: Wellcome Sanger Institute: The Garnett lab are seeking a Senior Bioinformatician to play a pivotal role in the development of innovative cancer drug combinations therapies. M... Cambridgeshire
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