Funding Opportunity PAR-22-037 from the NIH Guide for Grants and Contracts. The neurovascular unit involves multiple pathways that contribute to neurodegeneration. Astrocytes, due to their overlapping roles regulating the blood brain barrier, neuronal health and response to degenerating cells, are uniquely positioned to be therapeutic targets. Astrocytes are a fundamental component of the neurovascular unit and are known to play a role in regulating the blood brain barrier and APOE signaling. However, the mechanistic role of astrocytes for the neurovascular unit in health and disease, including in vascular contributions to cognitive impairment and dementia (VCID) and across the spectrum of AD/ADRD diagnoses, is largely unknown, and represents a gap area and an opportunity for research investment. This initiative would represent the first targeted initiative on the fundamental role of astrocytes in AD/ADRD at the NIH.

Notice NOT-NR-21-008 from the NIH Guide for Grants and Contracts

Notice NOT-NR-21-009 from the NIH Guide for Grants and Contracts

This position will include working animal husbandry, cell culture, DNA / RNA extraction, qPCR, CRISPR assays and basic cloning, and fluorescent microscopy…
From University of Wisconsin–Madison - Wed, 29 Sep 2021 18:57:24 GMT - View all Madison, WI jobs

Funding Opportunity PAR-21-346 from the NIH Guide for Grants and Contracts. The purpose of this limited competition Funding Opportunity Announcement (FOA) is to continue support for the Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (Consortium) that will be focused on prevention, diagnosis, treatment, and mechanisms of treatment resistance in SCLC. The CC will support the administrative coordination of the SCLC Consortium, create and support database(s) for -omics or other data pertinent to the Consortium, secure centralized tissue banking for specimens submitted by the members of the Consortium and a virtual biospecimen database that would include all tissue resources of the Consortium, provide centralized biostatistics, bioinformatics and data analysis support, establish SCLC in vivo and in vitro model repositories and distribution units, support meeting and communications coordination among members of Consortium, and form and maintain a Consortium website.

Notice NOT-NS-22-029 from the NIH Guide for Grants and Contracts

Notice NOT-TR-21-035 from the NIH Guide for Grants and Contracts

Notice NOT-CA-21-122 from the NIH Guide for Grants and Contracts

Notice NOT-RM-22-001 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-21-351 from the NIH Guide for Grants and Contracts. The purpose of the NIA Career Transition Award (CTA) is to facilitate the transition of mentored researchers to tenure-track faculty conducting research that advances the mission of NIA. This three-year award provides protected time through salary and research support and is targeted at applicants who plan to start a tenure-track faculty position within a year of the award.

Funding Opportunity PAR-21-344 from the NIH Guide for Grants and Contracts. To develop and/or pilot test interventions for HIV/AIDS-associated stigma and its outcome on the prevention and treatment of HIV/AIDS and on the quality of life of People Living with HIV/AIDS (PLWH). Specifically, this initiative will support research on or leading to interventions to address a) innovation in measurement of HIV-associated stigma and of other intersecting stigmas due to multiple morbidities to develop better interventions, b) stigma and adolescent and/or youth health, c) effects of stigma on family members or care givers of PLWH, and on the aging PLWH, d) novel stigma reduction interventions that link to increase in care-seeking behavior and/or decrease in transmission and e) coping with the complexity of added burden of stigmatization due to HIV and to one or more comorbidities/coinfections.

Funding Opportunity PAR-22-021 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for institutional research training programs in Alzheimers Disease/Alzheimers Disease-Related Dementias (AD/ADRD). These institutional research training programs should produce well-trained neuroscientists who leave the program with the research skills and scientific knowledge to make a significant contribution to research on AD/ADRD cognitive impairment and dementia. Programs should be designed to enhance the breadth and depth of training across the spectrum AD/ADRD research areas (e.g. AD, Vascular Contributions to Cognitive Impairment and Dementia (VCID), Lewy Body Dementia (LBD), Fronto-temporal Dementia (FTD) and mixed dementias) by incorporating didactic, research and career development components within this theme into a program that fosters exceptional research skills and knowledge. Programs may support basic, clinical and/or translational research. Programs supported by this FOA must include formal components to ensure a thorough understanding of experimental design, statistical principles and methodological approaches, analytical skills, and skills for communicating science, both orally and in writing, to a wide variety of audiences. All programs are expected to design and/or provide opportunities and activities that will foster the development of quantitative literacy and the application of quantitative approaches to the trainees' research. These training programs are intended to be 2 years in duration and support training of one or more of the following groups: dissertation stage predoctoral students in their 3rd and/or 4th year of graduate school, postdoctoral fellows and fellowship-stage clinicians. (NINDS does not support first or second year graduate students under this FOA).

Funding Opportunity PAR-21-348 from the NIH Guide for Grants and Contracts. The role of EBV infection on Non-Hodgkin Lymphoma (NHL) and Hodgkin disease (HD) development with or without an underlying HIV infection and AIDS will increase our understanding through mechanistic, epidemiological, or translational studies that examine how EBV promotes NHL or HD initiation, progression and the resulting disease sequelae. In addition, insights into mechanistic differences of EBV infection and lymphomagenesis between HIV positive and HIV negative persons will be gained.

£40000 - £45000 per annum: Hyper Recruitment Solutions (HRS): We are currently looking for a Bioinformatics Post Doc to join a leading pharmaceutical company based in the Slough, Berkshire area. As the Bioinformatics Post... Slough

Funding Opportunity RFA-AI-21-065 from the NIH Guide for Grants and Contracts. The purpose of the Funding Opportunity Announcement (FOA) is to support research that employs systems biology approaches to human pathogens. The approach will generate and integrate large datasets into models that guide in vitro, in vivo and clinical studies, with the goals of predicting disease severity, predicting responses to vaccines and therapeutics, and identifying candidate targets for interventions.

Competitive Salary: F. Hoffmann-La Roche AG: In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some o Switzerland (CH)

Notice NOT-AI-21-074 from the NIH Guide for Grants and Contracts

Notice NOT-OD-21-187 from the NIH Guide for Grants and Contracts

£32,780-£41,093: Wellcome Sanger Institute: Vento-Tormo’s lab research interest is to understand the influence of cellular microenvironments on individual cellular identities and responses, i... Hinxton, Cambridgeshire

Funding Opportunity PAR-21-326 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites qualified academic or research institutions to apply for support to purchase and install advanced equipment to enhance and modernize research-supporting operations of biomedical research facilities. Targeted are core facilities, animal research facilities, and other research spaces that are used on a shared basis. The goal of this FOA is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficacy of their operation. To ensure proper installation and functioning of the equipment, minor alteration and renovation (A and R) efforts can be included as a small component of the budget.