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BRAIN Initiative: Biology and Biophysics of Neural Stimulation and Recording Technologies (R01 Clinical Trials Optional)

Funding Opportunity RFA-NS-20-006 from the NIH Guide for Grants and Contracts. A central goal of the BRAIN Initiative is to develop new and improved technologies suitable for recording from as well as controlling specified cell types and circuits to modulate and understand function in the central nervous system. In order to accomplish these goals, further information is needed to understand the function of current technologies used for recording or stimulating the nervous system. This RFA accepts grant applications in two related but distinct areas. The first is to systematically characterize, model, and validate the membrane, cellular, circuit, and adaptive-biological responses of neuronal and non-neuronal cells to various types of stimulation technologies. The second is to understand the biological and bioinformatic content of signals recorded from neuronal and non-neuronal cells and circuits. Development of new technologies, therapies and disease models, are outside the scope of this FOA. Activities related to enabling the simultaneous use of multiple recording or stimulation technologies are allowed.

Surgical Disparities Research (R01 - Clinical Trial Optional)

Funding Opportunity PAR-20-079 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support investigative and collaborative research focused on understanding and addressing disparities in surgical care and outcomes, in minority and health disparity populations. While the goal is to better understand and explore effectiveness of clinical intervention approaches for addressing surgical disparities, this initiative will also seek to identify multi-level strategies at the institutional and systems level.

Instructor, Biology - Laramie County Community College - Cheyenne, WY

Indeed.com - Bioinformatics - Mon, 2019-12-30 12:22
One year of experience with specialized instrumentation and techniques (microscopy, bioinformatics, statistics, etc.). This is a 9-Month, Faculty 5 position. $51,373 - $61,647 a year
From Laramie County Community College - Mon, 30 Dec 2019 17:22:21 GMT - View all Cheyenne, WY jobs
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Metabolism Investigator - Morgridge Institute for Research - Madison, WI

Indeed.com - Bioinformatics - Mon, 2019-12-30 12:09
Applicants should submit electronic copies of their curriculum vitae, a 2–3-page description of research vision and future research plans, a 1-page description…
From Morgridge Institute for Research - Mon, 30 Dec 2019 17:09:28 GMT - View all Madison, WI jobs
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Request for Information (RFI): ClinicalTrials.gov Modernization

Notice NOT-LM-20-003 from the NIH Guide for Grants and Contracts

White Matter Lesion Etiology of Dementia in the U.S. Including in Health Disparity Populations (U19 Clinical Trial not Allowed)

Funding Opportunity RFA-NS-20-013 from the NIH Guide for Grants and Contracts. Despite established associations between white matter lesions and cognitive impairment including dementia, the volume, anatomical location, and other key cellular and molecular characteristics of white matter lesions that are both necessary and sufficient are unknown, as are the comorbid clinical factors that may modify (including protect from) these effects. Therefore, this initiative will support one large prospective clinical research study in the U.S. studying individuals with white matter lesions at risk for cognitive decline to determine the magnitude and anatomical locations that are both necessary and sufficient to cause cognitive impairment and dementia. The study will include health disparities populations, and will examine additional clinical factors and comorbidities that may be effect modifiers of the relationship between white matter lesions and cognitive impairment, including dementia. Clinical trial-ready VCID biomarkers should be utilized, further developed, and/or subject to implementation research in this study. Secondary goals include: identifying clinical and mechanistic targets for future VCID interventional trials; determining interrelationships (cross-sectional and longitudinal) among white matter lesions, cerebro- and cardio-vascular disease and risk factors including dementia-relevant genes. Applicants are encouraged, when scientifically advantageous, to utilize existing resources for VCID and stroke research, e.g. MarkVCID, StrokeNet, Alzheimers Centers, and large NIH funded prospective cohort studies (e.g. Framingham, ARIC, CHS, NOMAS, etc.) as well as other dementia resources.

Bioinformatics Manager - Medical College of Wisconsin - Milwaukee, WI

Indeed.com - Bioinformatics - Thu, 2019-12-26 16:08
Leads the BDAU team in, or, if necessary, directly performs bioinformatics analysis on research or clinical samples to meet deadlines defined in SoW.
From Medical College of Wisconsin - Thu, 26 Dec 2019 21:08:44 GMT - View all Milwaukee, WI jobs
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Methods and Measurement in Research with Sexual and Gender Minority (SGM) Populations (R21- Clinical Trials Not Allowed)

Funding Opportunity RFA-MD-20-005 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support projects to advance the measurement of constructs relevant to health research with sexual and gender minority (SGM) populations.

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