Job Watch

Mechanistic Basis of TDP-43-dependent Pathobiology in Common Dementias (R01 Clinical Trial not Allowed)

Funding Opportunity RFA-NS-20-005 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support hypothesis-testing research on the systems, cellular and/or molecular mechanisms and consequences of TDP-43 proteinopathy in common dementias using whole animal models, animal/human cellular model systems, as well as postmortem tissue and other biospecimens. Research on TDP-43 proteinopathy in common dementias, including the clinical syndrome of Alzheimer's disease (AD), multiple etiology dementias (MED) and related dementia syndromes is the focus of this FOA. In addition, comparative studies of TDP-43 proteinopathy in common and rare neurodegenerative diseases, as well as during normal aging and in pre-symptomatic disease stages are within scope.

Peripheral Pathology in the Lewy Body Dementias (R01 Clinical Trial Not Allowed)

Funding Opportunity RFA-NS-20-014 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to identify potential biomarkers for the Lewy Body Dementias using non-blood or CSF peripheral specimens and tissues (e.g., autonomic nervous system, skin, salivary gland, GI tract/microbiome, olfactory mucosa, etc.). Blood and CSF have traditionally and extensively been examined for neurodegenerative disease biomarkers; however, research suggests that abnormal alpha-synuclein accumulation occurs in other peripheral tissues and specimens pre-symptomatically and may provide opportunities for early diagnosis and future treatment development.

Paramount Recruitment: Clinical Bioinformatician

New Scientist - Bioinformatics - Thu, 2019-09-05 06:37
Negotiable: Paramount Recruitment: Clinical Bioinformatician London To build on the success of the 100,000 Genomes Project, the Government tasked NHS England with support from Genomics London, England
Categories: Job Watch

EMBL: Ensembl Web Back-end Developer

New Scientist - Bioinformatics - Thu, 2019-09-05 05:39
Competitive Salary: EMBL: Ensembl Web Back-end Developer Location: Cambridge, Cambridgeshire, England
Categories: Job Watch

Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)

Funding Opportunity PAR-19-363 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.

Notice of Special Interest (NOSI) of NIDCD and NEI in Supporting Research on Usher Syndrome

Notice NOT-DC-19-007 from the NIH Guide for Grants and Contracts

EMBL: Ensembl Applications Developer

New Scientist - Bioinformatics - Wed, 2019-09-04 05:39
Competitive Salary: EMBL: Ensembl Applications Developer Location: Cambridge, Cambridgeshire, England
Categories: Job Watch

EMBL: UI/UX Designer

New Scientist - Bioinformatics - Wed, 2019-09-04 05:36
Competitive Salary: EMBL: UI/UX Designer Location: EMBL-EB Cambridge, Cambridgeshire, England
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