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Paramount Recruitment: Home or Office Contract Bioinformatician - 8-9 month project

New Scientist - Bioinformatics - Tue, 2018-03-06 02:11
Negotiable: Paramount Recruitment: Home or Office Contract Bioinformatician - 8-9 month project Full time - UK or Europe - Translational Bioinformatics - NGS Anal A great opportunity is available for a Bioinformatician to join a global Bio-Pharma based in the UK. Berkshire, England
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NEI Translational Research Program (TRP) on Therapy for Visual Disorders (R24 Clinical Trial Optional)

Funding Opportunity PAR-18-707 from the NIH Guide for Grants and Contracts. The purpose of this FOA is the rapid and efficient translation of innovative laboratory research findings into therapies, devices or other resources for use by clinicians to treat visual system diseases or disorders. Multidisciplinary teams of scientists and clinicians will focus on generating preclinical data that will lead to the development of biological interventions, such as gene therapy, cell-based therapy, pharmacological approaches, and/or medical devices. The ultimate goal of this program is to make technological, biological and pharmacological resources available to clinicians and their patients.

Selective Cell and Network Vulnerability in Aging and Alzheimers Disease (R01 - Clinical Trial Not Allowed)

Funding Opportunity PAR-18-706 from the NIH Guide for Grants and Contracts. The goal of this FOA is to define and characterize neural cell populations, neural circuits, and brain networks and regions that are vulnerable to brain aging and Alzheimers disease (AD). Understanding mechanisms underlying selective vulnerability from cells to networks in AD is critical to fully define the disease process and to develop effective therapies.

Science-Based Quality Measurement and Management Development for Opioid Use Disorder Treatment (R61/R33 Clinical Trial Required)

Funding Opportunity RFA-DA-19-005 from the NIH Guide for Grants and Contracts. This FOA solicits applications proposing phased research projects, with transition milestones, to develop and rigorously test the effects of strategies to improve opioid treatment quality measures, both on changes in the measures themselves and on patient outcomes. The overall goal is to advance the field of clinical quality measurement and management in opioid use disorder treatment by generating research better aligning quality measurement with quality improvement.

High Priority HIV/AIDS Research within the Mission of the NIDDK (R01 Clinical Trial Optional)

Funding Opportunity PAS-18-698 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks to stimulate HIV/AIDS research within the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that addresses high priority HIV/AIDS research priorities outlined by the NIH Office of AIDS Research (OAR). These priorities are described in NOT-OD-15-137: NIH HIV/AIDS Research Priorities and Guidelines for Determining AIDS Funding.

Safe and Effective Devices for Use In Neonatal, Perinatal and Pediatric Care Settings (R43/R44 Clinical Trial Optional)

Funding Opportunity RFA-HD-19-001 from the NIH Guide for Grants and Contracts. A major objective of this funding opportunity announcement (FOA) is to invite SBIR applications to foster collaboration between clinical and bioengineering research communities to develop and test safe, accurate, and effective devices for use in neonatal, perinatal, and pediatric care settings. These can be new devices or improvements on existing devices. The studies may range from concept to developmental phases, with a clear commercialization plan to enable healthcare providers to use them in regular clinical care settings in the population, which is the focus of this FOA.

Basic and Translational Oral Health Research Related to HIV/AIDS (R21 Clinical Trial Not Allowed)

Funding Opportunity PA-18-695 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages innovative basic and translational exploratory research into mechanisms of HIV transmission, persistence, pathogenesis and co-morbidities in the oral cavity.

Basic and Translational Oral Health Research Related to HIV/AIDS (R01 Clinical Trial Not Allowed)

Funding Opportunity PA-18-699 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages innovative basic and translational research into mechanisms of HIV transmission, persistence, pathogenesis and co-morbidities in the oral cavity.

Announcement of 3-D Retina Organoid Challenge (3-D ROC)

Notice NOT-EY-18-006 from the NIH Guide for Grants and Contracts

Stimulating T4 Implementation Research to Optimize Integration of Proven-effective Interventions for Heart, Lung, and Blood Diseases and Sleep Disorders into Practice (STIMULATE) (R01 Clinical Trial Not Allowed)

Funding Opportunity RFA-HL-19-014 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks late-stage T4 Translation research (T4TR) and implementation studies that will lead to generalizable new knowledge to accelerate the adoption/adaptation, and sustained, high-fidelity use of proven-effective interventions for the prevention, treatment, and control of heart, lung, blood, and sleep disorders or diseases (HLBS conditions). It calls for multi-level strategies for delivery of proven-effective interventions to promote the prevention and management of HLBS conditions. The system-level change(s) being evaluated are to be designed, and findings reported so that others would have a contextually-informed understanding of workflow, workforce, and trade-off considerations. These considerations should reflect cultural and organizational contextual factors and values as they inform feasibility and flexibility of adopting, adaptable and sustainable, proven-effective interventions to address HLBS conditions.

Natural Product, Multi-Site, Clinical Trial, Data Coordinating Center (Collaborative U24 - Clinical Trial Required)

Funding Opportunity PAR-18-697 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) , utilizing the U24 grant funding mechanism, encourages applications for a collaborating Data Coordinating Center (DCC) application that accompanies investigator-initiated, multi-site clinical trials (Phase III and beyond) applications submitted under PAR-18-124 (https://grants.nih.gov/grants/guide/pa-files/PAR-18-124.html). The DCC application must be specific to the collaborating Clinical Coordinating Center (CCC) application. The objective of the DCC application Is lo propose a, comprehensive plan that provides overall project coordination. and administrative, data management and biostatistical support for the proposed clinical trial. Both a DCC application and a corresponding CCC application need to be submitted simultaneously for consideration by NCCIH. Trials for which this FOA applies must be relevant to the research mission of the NCCIH and considered a high priority by the Center. For additional information about the mission, strategic vision, and research priorities of the NCCIH, applicants are encouraged to consult the NCCIH website: (https://www,nocih.nih.gov) . Applicants are encouraged to contact the appropriate Scientific/Research contact for the area of science for which they are planning to develop an application prior lo submitting to this FOA.

Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)

Funding Opportunity PAR-18-696 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages cooperative agreement applications for investigator-initiated multi-site clinical trials (Phase III and beyond) to study the effects of natural products in NCCIH designated areas of high research priority. Applicants should describe plans for a Clinical Coordinating Center to develop and implement the proposed multi-site clinical trial. The objective of the Clinical Coordinating Center is to provide the design scientific rationale and a comprehensive scientific and operational plan for the clinical trial. The Clinical Coordinating Center is expected to be responsible for project management, participant recruitment and retention strategies, performance milestones, scientific conduct, and dissemination of results. Clinical Coordinating Center applications submitted under this FOA will utilize a two-phase, milestone-driven cooperative agreement (UG3/UH3) funding mechanism. In addition, an accompanying Data Coordinating Center application, submitted under PAR-18-123 (https://grants.nih.gov/grants/guide/pa-files/PAR-18-123.html), proposing a data analysis and data management plan for the clinical project is required. Both a Clinical Coordinating Center application and a corresponding Data Coordinating Center (DCC) application need to be submitted simultaneously for consideration by NCCIH.

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