Notice NOT-DK-24-006 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-082 from the NIH Guide for Grants and Contracts. As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer or structural birth defect cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of structural birth defects, to study the molecular basis of the associations between birth defects and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts of underrepresented racial and ethnic groups or to increase racial and ethnic representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.

Funding Opportunity PAR-24-078 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.

Notice NOT-GM-24-013 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-319 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) participating Institutes and Centers (ICs), in collaboration with the Global Alliance for Chronic Diseases (GACD), invite applications for implementation research focused on addressing risk factors for common noncommunicable diseases (NCDs) in World Bank-defined low- and middle-income countries (LMICs) and American Indian/Alaska Native (AI/AN) Tribal Nation populations in the United States. This Funding Opportunity Announcement (FOA) supports innovative approaches to identifying, understanding, developing, and implementingstrategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, tools, policies, and guidelines. In addition, studies to advance dissemination and implementation research methods and measures into application are encouraged. Specifically, this FOA invites applications that propose implementation research targeted to reducing the risks of NCDs in the context of cities in LMICs and/or among AI/AN Tribal Nation populations in cities in the United States, with the potential to equip policymakers and practitioners with evidence-based strategies for prevention and/or management of NCDs among disadvantaged populations globally. In the context of this FOA, "cities" include urban centers, informal settlements and slums, and periurban areas.

Notice NOT-NR-24-004 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-091 from the NIH Guide for Grants and Contracts. This NOFO invites applications at the intersection of HIV and aging by proposing research that aims to meet the following objectives: 1) Improve the understanding of biological, clinical, and socio-behavioral aspects of aging through the lens of HIV infection and its treatment; and 2) Improve approaches for testing, preventing, and treating HIV infection, and managing HIV-related comorbidities, co-infections, and complications in different populations and cultural settings by applying current aging science approaches. Proposed research must be consistent with the HIV/AIDS Research Priorities outlined by NIHs Office of AIDS Research (OAR), as described inNOT-OD-20-018.

Funding Opportunity PAR-24-092 from the NIH Guide for Grants and Contracts. This NOFO invites applications at the intersection of HIV and aging by proposing research that aims to meet the following objectives: 1) Improve the understanding of biological, clinical, and socio-behavioral aspects of aging through the lens of HIV infection and its treatment; and 2) Improve approaches for testing, preventing, and treating HIV infection, and managing HIV-related comorbidities, co-infections, and complications in different populations and cultural settings by applying current aging science approaches. Proposed research must be consistent with the HIV/AIDS Research Priorities outlined by NIHs Office of AIDS Research (OAR), as described inNOT-OD-20-018.

Notice NOT-AG-23-075 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-015 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-038 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-ES-23-012 from the NIH Guide for Grants and Contracts. The goal of this NIEHS undergraduate research education R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce in the environmental health sciences. To this end, this funding opportunity announcement (FOA) encourages the development of creative educational activities with a primary focus on research experiences for undergraduates at the junior and senior level.

Funding Opportunity PAR-24-038 from the NIH Guide for Grants and Contracts. The objective of this Notice of Funding Opportunity (NOFO) is to solicit applications to conduct institutional climate assessments using validated survey instruments and to develop action plans for positive change in the recruitment, hiring, retention, and advancement of faculty, including those from groups underrepresented in biomedical and behavioral research (see NIH Interest in Diversity). The plans for self-studies should lead to institutional culture change by identifying perceptions, attitudes, and concerns, about, for example, inequities, micro-aggressions, institutional racism, and bias. The self-studies should provide a foundation for the development of an action plan to enhance diversity, equity, inclusion, and accessibility (DEIA) outcomes in the recruitment, hiring, retention, and advancement of faculty.

Notice NOT-OD-24-041 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-006 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-017 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-015 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-25-010 from the NIH Guide for Grants and Contracts. The Notice of Funding Opportunity (NOFO) aims to support research addressing the interplay of autophagy orchestrated cell death and HIV pathogenesis with a focus on the CNS cellular immune responses influenced by acute and chronic drug use.

Funding Opportunity RFA-DA-25-009 from the NIH Guide for Grants and Contracts. The Notice of Funding Opportunity (NOFO) aims to address the interplay of autophagy orchestrated cell death and HIV pathogenesis with a focus on the CNS cellular immune responses influenced by acute and chronic drug use.

Funding Opportunity RFA-CA-24-021 from the NIH Guide for Grants and Contracts. The National Cancer Institute (NCI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) soliciting UG3/UH3 applications for the pediatric arm of the Cancer Adoptive Cellular Therapy (Can-ACT) Network. The overall goal of the NOFO is to advance new cell therapy strategies into clinical testing for the treatment of solid tumors in pediatric cancer patients (18 years or younger). The successful applications will add to -the newly established Cancer Adoptive Cellular Therapy (Can-ACT) Network, dedicated to developing innovative cell therapy approaches for the treatment of solid tumors in pediatric and adult tumors. The emphasis is on accelerating the advancement of new cell therapy strategies into clinical testing through novel and collaborative approaches to preclinical testing and translational studies. Can-ACT will support multi-investigator teams with the relevant expertise, assembled to bring new cell therapy products to the clinic.