Notice NOT-OD-23-144 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-143 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-142 from the NIH Guide for Grants and Contracts

Notice NOT-DK-23-028 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-024 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages research on the biology of high confidence risk factors associated with complex brain disorders, with a focus on the intracellular, transcellular and circuit substrates of neural function. For the purposes of this FOA, the term complex can refer to a multifactorial contribution to risk (e.g., polygenic and/or environmental) and/or highly distributed functional features of the brain disorder. Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. While behavioral paradigms and outcome measures can be incorporated into the research design to facilitate the characterization of intracellular, transcellular and circuit mechanisms, these are neither required nor expected. Studies should not attempt to model disorders but instead should aim to elucidate the neurobiological impact of individual or combined risk factor(s), such as the affected molecular and cellular components and their relationships within defined biological process(es). This can include the fundamental biology of these factors, components and processes. The resulting paradigms, component pathways and biological processes should be disseminated with sufficient detail to enrich common and/or federated data resources (e.g., those contributing to the Gene Ontology, Synaptic Gene Ontology, FAIR Data Informatics) in order to bridge the gap between disease risk factors, biological mechanism and therapeutic target identification. The present announcement seeks R01 applications.

Funding Opportunity PAR-24-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages research on the biology of high confidence risk factors associated with complex brain disorders, with a focus on the intracellular, transcellular and circuit substrates of neural function. For the purposes of this FOA, the term complex can refer to a multifactorial contribution to risk (e.g., polygenic and/or environmental) and/or highly distributed functional features of the brain disorder. Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ, or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. While behavioral paradigms and outcome measures can be incorporated into the research design to facilitate the characterization of intracellular, transcellular and circuit mechanisms, these are neither required nor expected. Studies should not attempt to model disorders but instead should aim to elucidate the neurobiological impact of individual or combined risk factor(s), such as the affected molecular and cellular components and their relationships within defined biological process(es). This can include the fundamental biology of these factors, components and processes. The resulting paradigms, component pathways and biological processes should be disseminated with sufficient detail to enrich common and/or federated data resources (e.g., those contributing to the Gene Ontology, Synaptic Gene Ontology, FAIR Data Informatics) in order to bridge the gap between disease risk factors, biological mechanism and therapeutic target identification. The present announcement seeks R21 applications for high risk or early stage exploratory research.

Notice NOT-OD-23-155 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-154 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-023 from the NIH Guide for Grants and Contracts. Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts

Funding Opportunity PAR-24-026 from the NIH Guide for Grants and Contracts. Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts

Notice NOT-MH-23-345 from the NIH Guide for Grants and Contracts

Notice NOT-RM-23-019 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-076 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-234 from the NIH Guide for Grants and Contracts. The objective of this FOA is to support a U24 Data Analysis and Coordination Center for the PsychENCODE Consortium, focused on the discovery and characterization of the full spectrum of human-specific non-coding functional genomic elements across brain regions, cell types, and developmental time periods and their role(s) in the molecular pathophysiology of psychiatric disorders. The center will support the integration, harmonization, analysis, management, and dissemination of Consortium data.

Funding Opportunity RFA-MH-24-100 from the NIH Guide for Grants and Contracts. This funding opportunity announcement encourages participatory data science and implementation science research to accelerate the implementation of more targeted and sustainable HIV interventions with the goals of: (1) using data science methods to model complex systems, including the social and structural determinants of health, to identify more targeted HIV prevention, treatment, and care interventions and implementation strategies; (2) using novel measurement approaches and modern statistical methods to evaluate the implementation of data-driven discoveries; and (3) integrating meaningful engagement of community and implementing partners at every stage of the research.

Funding Opportunity RFA-MD-24-002 from the NIH Guide for Grants and Contracts. NIMHD invites applications to support research to develop and test multilevel youth violence prevention interventions for populations that experience health disparities, which include strategies that address structural discrimination and other social determinants of health.

Funding Opportunity PA-23-189 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention hereby notify Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) holding specific types of research grants (activity codes listed above) that funds are available for administrative supplements to enhance the diversity of the research workforce by recruiting and supporting students, postdoctorates, and eligible investigators from diverse backgrounds, including those from groups that have been shown to be underrepresented in health-related research. This supplement opportunity is also available to PD(s)/PI(s) of research grants who are or become disabled and need additional support to accommodate their disability in order to continue to work on the research project. Administrative supplements must support work within the scope of the original project. This Notice of Funding Opportunity (NOFO) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this NOFO are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.

Notice NOT-MH-23-360 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-075 from the NIH Guide for Grants and Contracts

Notice NOT-HL-23-096 from the NIH Guide for Grants and Contracts