Notice NOT-NS-18-017 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-150 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-CA-18-020 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research projects designed to solve specific problems and paradoxes in cancer research identified by the National Cancer Institute (NCI) Provocative Questions initiative. These problems and paradoxes phrased as questions are not intended to represent the full range of NCI's priorities in cancer research. Rather, they are meant to challenge cancer researchers to think about and elucidate specific problems in key areas of cancer research that are deemed important but have not received sufficient attention. Some of these "Provocative Questions" (PQs) stem from intriguing but older, neglected observations that have never been adequately explored. Other PQs are built on more recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge. Finally, some PQs reflect problems that traditionally have been thought to be intractable but that now may be open to investigations using new strategies and recent technical advances. The current issuance of the PQ Initiative includes an updated set of 12 PQs. Each research project proposed in response to this FOA must be focused on addressing one particular research problem defined by one specific PQ selected from the list. Projects proposed to address specific PQs may use strategies that incorporate ideas and approaches from multiple disciplines, as appropriate. Transdisciplinary projects are encouraged as long as they serve the scientific focus of the specific PQ chosen.

Funding Opportunity RFA-CA-18-019 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research projects designed to solve specific problems and paradoxes in cancer research identified by the National Cancer Institute (NCI) Provocative Questions initiative. These problems and paradoxes phrased as questions are not intended to represent the full range of NCI's priorities in cancer research. Rather, they are meant to challenge cancer researchers to think about and elucidate specific problems in key areas of cancer research that are deemed important but have not received sufficient attention. Some of these "Provocative Questions" (PQs) stem from intriguing but older, neglected observations that have never been adequately explored. Other PQs are built on more recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge. Finally, some PQs reflect problems that traditionally have been thought to be intractable but that now may be open to investigations using new strategies and recent technical advances. The current issuance of the PQ Initiative includes an updated set of 12 PQs. Each research project proposed in response to this FOA must be focused on addressing one particular research problem defined by one specific PQ selected from the list. Projects proposed to address specific PQs may use strategies that incorporate ideas and approaches from multiple disciplines, as appropriate. Transdisciplinary projects are encouraged as long as they serve the scientific focus of the specific PQ chosen.

Notice NOT-DA-18-009 from the NIH Guide for Grants and Contracts

Notice NOT-AT-18-008 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-146 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-149 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-18-002 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to participate in the NIAID Autoimmunity Centers of Excellence (ACE), a cooperative network intended to improve the understanding, prevention, and treatment of autoimmune diseases (www.autoimmunitycenters.org). The ACE was founded on the premise that collaborations among basic and clinical scientists can accelerate both fundamental and applied research. The ACE combines Basic and Clinical research programs. This FOA solicits applications for the Basic research program; a companion FOA solicits applications for the Clinical research program. Members of the Basic research program will conduct innovative studies of human autoimmunity within Principal, Pilot, and Collaborative Projects. Members of the Basic and Clinical ACE will work together to design and conduct studies of autoimmune disease pathogenesis and mechanisms of action of immune-modulating agents being tested in ACE clinical trials.

Funding Opportunity RFA-AI-18-003 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to participate in the NIAID Autoimmunity Centers of Excellence (ACE), a cooperative network intended to improve the understanding, prevention, and treatment of autoimmune diseases (www.autoimmunitycenters.org). The ACE program was founded on the premise that collaborations among basic and clinical scientists can accelerate both fundamental and applied research. The ACE combines Basic and Clinical research programs. This FOA solicits applications for the Clinical research program; a companion FOA solicits applications for the Basic research program. Members of the Clinical research program will conduct innovative studies of human autoimmunity within Clinical and Collaborative Projects. Members of the Basic and Clinical ACE will work together to design and conduct studies of autoimmune disease pathogenesis and mechanisms of action of immune-modulating agents being tested in ACE clinical trials.

Notice NOT-OD-18-144 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-143 from the NIH Guide for Grants and Contracts

Notice NOT-HD-18-005 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-137 from the NIH Guide for Grants and Contracts

Notice NOT-OD-18-136 from the NIH Guide for Grants and Contracts

Notice NOT-EB-18-008 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DE-19-001 from the NIH Guide for Grants and Contracts. The National Institute of Dental and Craniofacial Research (NIDCR) intends to continue support for research conducted within a national Dental Practice-Based Research Network (DPBRN). The NIDCR will fund one national DPBRN Administrative and Resource Center led by a National Network Director and one national DPBRN Coordinating Center, funded with companion awards, to support the infrastructure for and implementation of multiple prospective observational studies and clinical trials. This funding opportunity announcement (FOA) is soliciting applications for the national DPBRN Administrative and Resource Center; a separate companion FOA is soliciting applications for the national DPBRN Coordinating Center (RFA-DE-19-002). The main goals of the cooperative agreement funded under this FOA are to maximize efficiencies to conduct national oral health research studies in dental practices on topics of importance to practitioners and their patients, to provide evidence useful in daily patient care, and to facilitate the translation of research findings into clinical practice. It is expected that the DPBRN will build on the significant investment to date by the NIDCR and will demonstrate continued growth and productivity.

Funding Opportunity RFA-DE-19-002 from the NIH Guide for Grants and Contracts. The National Institute of Dental and Craniofacial Research (NIDCR) intends to continue support for research conducted within a national Dental Practice-Based Research Network (DPBRN). The NIDCR will fund one national DPBRN Administrative and Resource Center led by a National Network Director and one national DPBRN Coordinating Center, funded as companion awards, to support the infrastructure for and implementation of multiple prospective observational studies and clinical trials. This funding opportunity announcement (FOA) is soliciting applications for the national DPBRN Coordinating Center; a separate FOA is soliciting applications for the national DPBRN Administrative and Resource Center (RFA-DE-19-002 ). This clinical research network will develop and conduct multiple prospective, observational clinical studies and clinical trials, on topics of interest to practitioners and their patients. Studies will be conducted in participating dental offices with consenting patients. The role of the national Coordinating Center will be to centralize and harmonize study operations, data management, and biostatistical support, to facilitate rapid development and implementation of oral health studies conducted in the national DPBRN.

Notice NOT-OD-18-135 from the NIH Guide for Grants and Contracts

Notice NOT-AT-18-009 from the NIH Guide for Grants and Contracts