Notice NOT-OD-17-095 from the NIH Guide for Grants and Contracts

Notice NOT-OD-17-096 from the NIH Guide for Grants and Contracts

Notice NOT-MH-17-039 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-17-335 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) intends to support investigators who have interest and capability to join efforts for the discovery of cell-based chemical probes for novel brain targets. It is expected that applicants will have in hand the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds. Through this FOA, NIH wishes to stimulate research in: 1) discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of NIMH, NIA, and/or NIDCD; and 2) discovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms. Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes. The main emphasis of projects submitted under this FOA should be in the discovery of cell-based chemical probes. Applicants interested in developing in vivo chemical probes may wish to apply using the companion R01 mechanism (PAR-17-336).

Funding Opportunity PAR-17-336 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) intends to support investigators who have interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have in hand the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds. Through this FOA, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of NIMH, NEI, NIAAA, NIDA, NIA and/or NIDCD and 2) discovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms. Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.

Funding Opportunity PAR-17-333 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support innovative exploratory/developmental investigations on primary immunodeficiency diseases focusing on ex vivo studies with human specimens and on studies with current or new animal models including novel clinical strategies for detecting, identifying the molecular basis of, or developing innovative therapies for primary immunodeficiency diseases. In addition, this FOA aims to encourage analyses of clinical data and samples maintained in primary immunodeficiency registries, consortium databases and repositories to address questions relevant to primary immunodeficiency research.

Notice NOT-AA-17-008 from the NIH Guide for Grants and Contracts

Notice NOT-RM-17-035 from the NIH Guide for Grants and Contracts

Notice NOT-AR-17-018 from the NIH Guide for Grants and Contracts

Notice NOT-AG-17-012 from the NIH Guide for Grants and Contracts

Notice NOT-AG-17-013 from the NIH Guide for Grants and Contracts

Notice NOT-TW-17-006 from the NIH Guide for Grants and Contracts

Notice NOT-TW-17-007 from the NIH Guide for Grants and Contracts

Notice NOT-GM-17-015 from the NIH Guide for Grants and Contracts

Notice NOT-HL-17-527 from the NIH Guide for Grants and Contracts

Notice NOT-HL-17-528 from the NIH Guide for Grants and Contracts

Notice NOT-NS-17-036 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-HD-18-012 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) will use the specialized research center mechanism (P50) to call for multidisciplinary centers to serve as the CAPSTONE for research on child abuse and neglect and to serve as a national resource for the field. The Center(s) will conduct innovative and high quality research including: 1) trials testing the efficacy and effectiveness of clinical interventions; 2) longitudinal prospective studies examining the long term effects of specific and understudied types of maltreatment including abusive head trauma, medical child abuse and neglect, chronic sexual abuse; 3) studies examining the neurobiology of abuse and neglect and implications for health outcomes; and 4) studies testing the development of screening tools and clinical assessment measures for early identification and treatment of specific types of abuse and neglect to decrease morbidity and mortality and to identify potential comorbidities. The Centers are also required to propose a community engagement core which will provide opportunities for students and faculty at all levels, to be exposed to cutting edge educational tools and technologies, research, and expertise within the field of child maltreatment. A central goal of this core will be to engage the scientific and lay professional communities in participatory activities such as technical assistance, evidence-based practice, participation in grand rounds, conferences and seminars, or webinars based on information emanating from the other cores. The format for the community engagement activities will be tailored to the expertise of the Center and the needs of the community.

Notice NOT-OD-17-093 from the NIH Guide for Grants and Contracts

Notice NOT-OD-17-092 from the NIH Guide for Grants and Contracts