Drug Repositioning
Identification of potential pathways and biomarkers linked to progression in ALS
Ann Clin Transl Neurol. 2022 Dec 19. doi: 10.1002/acn3.51697. Online ahead of print.
NO ABSTRACT
PMID:36533811 | DOI:10.1002/acn3.51697
The design of compounds with desirable properties - The anti-HIV case study
J Comput Chem. 2022 Dec 19. doi: 10.1002/jcc.27061. Online ahead of print.
NO ABSTRACT
PMID:36533526 | DOI:10.1002/jcc.27061
Spray freeze dried niclosamide nanocrystals embedded dry powder for high dose pulmonary delivery
Powder Technol. 2022 Dec 13:118168. doi: 10.1016/j.powtec.2022.118168. Online ahead of print.
NO ABSTRACT
PMID:36533138 | PMC:PMC9746026 | DOI:10.1016/j.powtec.2022.118168
LC-MS/MS method for simultaneous quantification of ten antibiotics in human plasma for routine therapeutic drug monitoring
J Mass Spectrom Adv Clin Lab. 2022 Nov 18;26:48-59. doi: 10.1016/j.jmsacl.2022.11.001. eCollection 2022 Nov.
NO ABSTRACT
PMID:36532696 | PMC:PMC9756784 | DOI:10.1016/j.jmsacl.2022.11.001
Drug Repurposing: a Shortcut to New Biological Entities
Pharm Chem J. 2022;56(9):1203-1214. doi: 10.1007/s11094-022-02778-w. Epub 2022 Dec 7.
NO ABSTRACT
PMID:36531825 | PMC:PMC9734433 | DOI:10.1007/s11094-022-02778-w
Integrated genomic analysis to identify druggable targets for pancreatic cancer
Front Oncol. 2022 Dec 1;12:989077. doi: 10.3389/fonc.2022.989077. eCollection 2022.
NO ABSTRACT
PMID:36531045 | PMC:PMC9752886 | DOI:10.3389/fonc.2022.989077
Novel antimicrobial agents targeting the <em>Streptococcus mutans</em> biofilms discovery through computer technology
Front Cell Infect Microbiol. 2022 Dec 1;12:1065235. doi: 10.3389/fcimb.2022.1065235. eCollection 2022.
NO ABSTRACT
PMID:36530419 | PMC:PMC9751416 | DOI:10.3389/fcimb.2022.1065235
Emerging Therapeutics Agents and Recent Advances in Drug Repurposing for Alzheimer's Disease
Ageing Res Rev. 2022 Dec 15:101815. doi: 10.1016/j.arr.2022.101815. Online ahead of print.
NO ABSTRACT
PMID:36529440 | DOI:10.1016/j.arr.2022.101815
Drug repurposing based novel anti-leishmanial drug screening using <em>in-silico</em> and <em>in-vitro</em> approaches
J Biomol Struct Dyn. 2022;40(21):10812-10820. doi: 10.1080/07391102.2021.1950574. Epub 2021 Jul 11.
NO ABSTRACT
PMID:36529188 | DOI:10.1080/07391102.2021.1950574
Contraceptive use and contraceptive counselling interventions for women of reproductive age with cancer: a systematic review and meta-analysis
BMC Med. 2022 Dec 17;20(1):489. doi: 10.1186/s12916-022-02690-w.
NO ABSTRACT
PMID:36528586 | DOI:10.1186/s12916-022-02690-w
Drug repurposing: From the discovery of a useful pharmacological effect to making the treatment available to the patient
Therapie. 2022 Dec 5:S0040-5957(22)00273-6. doi: 10.1016/j.therap.2022.11.009. Online ahead of print.
NO ABSTRACT
PMID:36528417 | DOI:10.1016/j.therap.2022.11.009
Uncovering the gene regulatory network of type 2 diabetes through multi-omic data integration
J Transl Med. 2022 Dec 16;20(1):604. doi: 10.1186/s12967-022-03826-5.
NO ABSTRACT
PMID:36527108 | DOI:10.1186/s12967-022-03826-5
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair
Adv Sci (Weinh). 2022 Dec 16:e2203053. doi: 10.1002/advs.202203053. Online ahead of print.
NO ABSTRACT
PMID:36526599 | DOI:10.1002/advs.202203053
Radotinib attenuates TGFβ -mediated pulmonary fibrosis in vitro and in vivo: exploring the potential of drug repurposing
BMC Pharmacol Toxicol. 2022 Dec 15;23(1):93. doi: 10.1186/s40360-022-00634-x.
NO ABSTRACT
PMID:36522756 | DOI:10.1186/s40360-022-00634-x
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
J Immunother Cancer. 2022 Dec;10(12):e005002. doi: 10.1136/jitc-2022-005002.
NO ABSTRACT
PMID:36521927 | DOI:10.1136/jitc-2022-005002
Synergistic Combinations of FDA-Approved Drugs with Ceftobiprole against Methicillin-Resistant Staphylococcus aureus
Microbiol Spectr. 2022 Dec 15:e0372622. doi: 10.1128/spectrum.03726-22. Online ahead of print.
NO ABSTRACT
PMID:36519895 | DOI:10.1128/spectrum.03726-22
Molecular dynamics simulation and docking analysis of NF-κB protein binding with sulindac acid
Bioinformation. 2022 Mar 31;18(3):170-179. doi: 10.6026/97320630018170. eCollection 2022.
NO ABSTRACT
PMID:36518123 | PMC:PMC9722428 | DOI:10.6026/97320630018170
Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors
Eur J Med Chem. 2022 Dec 6;246:115011. doi: 10.1016/j.ejmech.2022.115011. Online ahead of print.
NO ABSTRACT
PMID:36516582 | DOI:10.1016/j.ejmech.2022.115011
A network medicine approach for identifying diagnostic and prognostic biomarkers and exploring drug repurposing in human cancer
Comput Struct Biotechnol J. 2022 Nov 29;21:34-45. doi: 10.1016/j.csbj.2022.11.037. eCollection 2023.
NO ABSTRACT
PMID:36514340 | PMC:PMC9732137 | DOI:10.1016/j.csbj.2022.11.037
Vir2Drug: a drug repurposing framework based on protein similarities between pathogens
Brief Bioinform. 2022 Dec 13:bbac536. doi: 10.1093/bib/bbac536. Online ahead of print.
NO ABSTRACT
PMID:36513376 | DOI:10.1093/bib/bbac536