Drug Repositioning
Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein
Acta Pharm Sin B. 2022 Dec;12(12):4378-4389. doi: 10.1016/j.apsb.2022.05.023. Epub 2022 May 25.
NO ABSTRACT
PMID:36561997 | PMC:PMC9764067 | DOI:10.1016/j.apsb.2022.05.023
Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy
Front Immunol. 2022 Dec 6;13:1083788. doi: 10.3389/fimmu.2022.1083788. eCollection 2022.
NO ABSTRACT
PMID:36561763 | PMC:PMC9763584 | DOI:10.3389/fimmu.2022.1083788
Screening of GPCR drugs for repurposing in breast cancer
Front Pharmacol. 2022 Dec 6;13:1049640. doi: 10.3389/fphar.2022.1049640. eCollection 2022.
NO ABSTRACT
PMID:36561339 | PMC:PMC9763283 | DOI:10.3389/fphar.2022.1049640
Therapeutic potential of compounds targeting SARS-CoV-2 helicase
Front Chem. 2022 Dec 6;10:1062352. doi: 10.3389/fchem.2022.1062352. eCollection 2022.
NO ABSTRACT
PMID:36561139 | PMC:PMC9763700 | DOI:10.3389/fchem.2022.1062352
Nisoldipine Inhibits Influenza A Virus Infection by Interfering with Virus Internalization Process
Viruses. 2022 Dec 8;14(12):2738. doi: 10.3390/v14122738.
NO ABSTRACT
PMID:36560742 | DOI:10.3390/v14122738
In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity
Pharmaceutics. 2022 Nov 22;14(12):2563. doi: 10.3390/pharmaceutics14122563.
NO ABSTRACT
PMID:36559057 | DOI:10.3390/pharmaceutics14122563
Identification of Potential Treatments for Acute Lymphoblastic Leukemia through Integrated Genomic Network Analysis
Pharmaceuticals (Basel). 2022 Dec 14;15(12):1562. doi: 10.3390/ph15121562.
NO ABSTRACT
PMID:36559013 | DOI:10.3390/ph15121562
Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations
Pathogens. 2022 Nov 25;11(12):1420. doi: 10.3390/pathogens11121420.
NO ABSTRACT
PMID:36558754 | DOI:10.3390/pathogens11121420
Virtual Screening of FDA-Approved Drugs for Enhanced Binding with Mitochondrial Aldehyde Dehydrogenase
Molecules. 2022 Dec 10;27(24):8773. doi: 10.3390/molecules27248773.
NO ABSTRACT
PMID:36557906 | DOI:10.3390/molecules27248773
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the <em>Pseudomonas aeruginosa</em> Pathogenesis
Microorganisms. 2022 Dec 12;10(12):2455. doi: 10.3390/microorganisms10122455.
NO ABSTRACT
PMID:36557708 | DOI:10.3390/microorganisms10122455
Towards Effective Consensus Scoring in Structure-Based Virtual Screening
Interdiscip Sci. 2022 Dec 23. doi: 10.1007/s12539-022-00546-8. Online ahead of print.
NO ABSTRACT
PMID:36550341 | DOI:10.1007/s12539-022-00546-8
Drug repositioning for SARS-CoV-2 by Gaussian kernel similarity bilinear matrix factorization
Front Microbiol. 2022 Dec 5;13:1062281. doi: 10.3389/fmicb.2022.1062281. eCollection 2022.
NO ABSTRACT
PMID:36545200 | PMC:PMC9762482 | DOI:10.3389/fmicb.2022.1062281
scDrug: From single-cell RNA-seq to drug response prediction
Comput Struct Biotechnol J. 2022 Dec 1;21:150-157. doi: 10.1016/j.csbj.2022.11.055. eCollection 2023.
NO ABSTRACT
PMID:36544472 | PMC:PMC9747355 | DOI:10.1016/j.csbj.2022.11.055
Machine learning driven drug repurposing strategy for identification of potential RET inhibitors against non-small cell lung cancer
Med Oncol. 2022 Dec 21;40(1):56. doi: 10.1007/s12032-022-01924-4.
NO ABSTRACT
PMID:36542155 | DOI:10.1007/s12032-022-01924-4
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti-colorectal cancer effects in mice
Cell Biosci. 2022 Dec 21;12(1):206. doi: 10.1186/s13578-022-00944-x.
NO ABSTRACT
PMID:36539845 | DOI:10.1186/s13578-022-00944-x
In silico evaluation of potential intervention against SARS-CoV-2 RNA-dependent RNA polymerase
Phys Chem Earth (2002). 2022 Dec 15:103350. doi: 10.1016/j.pce.2022.103350. Online ahead of print.
NO ABSTRACT
PMID:36536697 | PMC:PMC9750507 | DOI:10.1016/j.pce.2022.103350
Pazopanib alleviates neuroinflammation and protects dopaminergic neurons in LPS-stimulated mouse model by inhibiting MEK4-JNK-AP-1 pathway
Acta Pharmacol Sin. 2022 Dec 19. doi: 10.1038/s41401-022-01030-1. Online ahead of print.
NO ABSTRACT
PMID:36536076 | DOI:10.1038/s41401-022-01030-1
Systematic comparison of differential expression networks in MTB mono-, HIV mono- and MTB/HIV co-infections for drug repurposing
PLoS Comput Biol. 2022 Dec 19;18(12):e1010744. doi: 10.1371/journal.pcbi.1010744. Online ahead of print.
NO ABSTRACT
PMID:36534703 | DOI:10.1371/journal.pcbi.1010744
Tyrosine Kinase Inhibitors Display Potent Activity against Cryptosporidium parvum
Microbiol Spectr. 2022 Dec 19:e0387422. doi: 10.1128/spectrum.03874-22. Online ahead of print.
NO ABSTRACT
PMID:36533912 | DOI:10.1128/spectrum.03874-22
Untargeted Metabolomics-Assisted Comparative Cytochrome P450-dependent Metabolism of Fenbendazole in Human and Dog Liver Microsomes
Xenobiotica. 2022 Dec 19:1-26. doi: 10.1080/00498254.2022.2160676. Online ahead of print.
NO ABSTRACT
PMID:36533905 | DOI:10.1080/00498254.2022.2160676