Notice NOT-CA-22-120 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-22-228 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications that employ integrative experimental and analytical approaches engaging basic and translational/clinical research aimed at developing a comprehensive understanding of the impact of sex differences on the trajectories of brain aging and disease, phenotypes of AD and AD-related dementias (ADRD) risk, individualized prevention, and responsiveness to pharmacologic and non-pharmacologic interventions. To this end, the central goal of this initiative is to develop robust research programs that will explore how genes, environment, and host factors such as hormonal status (gonadal and brain-derived) interact at various levels of biologic complexity (i.e., cell, tissue, organs/organ systems, and populations) to produce heterogeneous phenotypes of disease risk and responsiveness to prevention/therapy in AD/ADRD.

Funding Opportunity RFA-NS-22-061 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement invites applications from established investigators who strive to expand their research trajectories through the acquisition of new knowledge and skills in the areas of traumatic brain injury (TBI) as a risk factor for Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD). This funding opportunity encourages applications for short-term (2 yrs.) mentored career enhancement awards to further understand TBI as a risk factor for AD/ADRD. Two categories of candidates are targeted: (a) established TBI investigators who seek training with senior dementia researchers, and (b) established dementia researchers who seek training with senior TBI investigators.

Notice NOT-DK-22-024 from the NIH Guide for Grants and Contracts

Notice NOT-CA-22-099 from the NIH Guide for Grants and Contracts

Notice NOT-OD-22-199 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-022 from the NIH Guide for Grants and Contracts. *Note to ICs: Please do not join this announcement. Shared Interest must be completed systematically but the Type 4 submission is for NS R37 applications only. The National Institute of Neurological Disorders and Stroke (NINDS) Javits Neuroscience Investigator Award (R37) provides extended grant support to investigators with a history of exceptional performance and outstanding productivity. The objective of the NINDS Javits Award is to allow Javits awardees to obtain up to seven years of support in two segments: The initial phase of up to four years, and a second phase, providing an additional three years of support. This funding opportunity announcement is specifically for currently funded NINDS Javits recipients to request the second phase of the R37 award.

Funding Opportunity RFA-CA-22-032 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is a part of an initiative designed to establish a Liver Cancer Consortium to advance translational research focused on early detection of liver cancer. The Consortium will consist of a Data Management and Coordinating Center (DMCC, to be supported by this U24 FOA) and several Translational Research Centers (TRCs, to be supported by the companion U01 FOA, RFA-CA-22-031). The TRCs will conduct studies to improve the surveillance of liver cancer in high-risk populations, increase the fraction of liver cancer detected at an early stage, and better stratify patients at risk of developing liver cancer. The DMCC will support the TRCs and coordinate trans-Consortium activities with the following specific responsibilities: (1) Overall administrative and logistical coordination for the Liver Cancer Consortium; (2) Support for Consortium collaborative research studies and biospecimen collections, including protocol development, data processing, statistical support, and computational analysis; and (3) Consortium data management, including developing and maintaining an integrated database of research data generated by the consortium, as well as management of all data relevant to biospecimens used in TRC studies (including clinical data annotations, and specimen usage tracking). To achieve these goals, the DMCC is expected to provide multi-disciplinary expertise in liver cancer research, biomarkers for cancer detection, biostatistics, bioinformatics, and the information technology infrastructure to support data management for the Consortium.

Funding Opportunity RFA-CA-22-031 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is soliciting applications for a Liver Cancer Consortium focused on advancing translational research in the early detection of liver cancer. Translational Research Centers (TRCs) will conduct studies to improve the surveillance of liver cancer in members of high-risk populations, increase the fraction of liver cancer detected at an early stage, and better stratify patients at risk of developing liver cancer. A major collaborative effort of the TRCs will be establishing an integrated blood and image repository with annotated clinical data from patients found to have indeterminate nodules during liver cancer surveillance. To achieve these goals, each proposed TRC should include laboratory and clinical researchers with multi-disciplinary expertise in such areas as early cancer detection, biomarkers, cancer surveillance, imaging, and biospecimen science. The Consortium will consist of several Translational Research Centers (TRCs, to be supported by this U01 FOA) and a Data Management and Coordinating Center (DMCC, to be supported a companion U24 FOA, RFA-CA-21-032). The TRCs will be expected to interact closely with the DMCC and engage in collaborative activities with other members of the Liver Cancer Consortium.

Funding Opportunity RFA-CA-22-046 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for U54 Research Centers to form the Radiation Oncology-Biology Integration Network (ROBIN). The cadre of ROBIN Centers created through this FOA will establish an agile and effective national radiation oncology network infrastructure that collectively address critical hypothesis-based translational research knowledge gaps on the biological basis of responses in cancer patients who undergo radiation treatments.

Funding Opportunity RFA-AT-23-005 from the NIH Guide for Grants and Contracts. The National Center for Complementary and Integrative Health (NCCIH) intends to solicit applications for one research resource center to build an Open-Access Repository and Database for Anatomical and Physiological Correlates of Acupoints. This FOA will support the development and maintenance of a repository and database for commonly used acupoints along with key anatomical specifications and other relevant parameters as well as integration with other databases with physiological correlates. The ultimate integrated database should be suitable for data from human subjects in an open-access and searchable format. A parallel repository and database for an appropriate animal is also desired. This FOA will utilize a cooperative agreement funding mechanism, U24, to support the development and maintenance of the repository and database to serve the research community. The repository and database should select high quality research data and aim to bring transformative values to support rigorous research on acupuncture-related interventions, which may also benefit evidence-based clinical practices and education.

Notice NOT-OH-22-005 from the NIH Guide for Grants and Contracts

Notice NOT-OH-22-004 from the NIH Guide for Grants and Contracts

Notice NOT-HG-22-030 from the NIH Guide for Grants and Contracts

Notice NOT-HG-22-031 from the NIH Guide for Grants and Contracts

Notice NOT-DE-22-015 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-016 from the NIH Guide for Grants and Contracts

Notice NOT-HD-22-041 from the NIH Guide for Grants and Contracts

Notice NOT-TR-22-034 from the NIH Guide for Grants and Contracts

Notice NOT-HD-22-039 from the NIH Guide for Grants and Contracts