Funding Opportunity RFA-DA-23-032 from the NIH Guide for Grants and Contracts. NEPS Concept # 1875 This funding opportunity announcement (FOA)?is a part of?NIDAs Racial Equity Initiative.?This?multi-year,?multi-pronged effort?to address ?racial and ethnic inequities in NIDA's research portfolio. This FOA invites R01 applications to conduct research that will have a major impact in identifying, developing, implementing, or testing strategies to improve outcomes related to substance misuse, with a goal of preventing, reducing, or eliminating disparities in racial and ethnic minority populations in substance use, addiction, and related health consequences, including HIV. Community engaged research can facilitate rapid advances in this scientific area by ensuring relevant research questions with immediate applicability. As such, applications must be submitted by collaborative community partnered investigative teams who will conduct research projects that address issues prioritized by the relevant communities. No preliminary data are required. However, projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce desired outcomes.

Funding Opportunity RFA-DA-23-031 from the NIH Guide for Grants and Contracts. This initiative invites applications for DP1 awards to support exceptionally creative early career investigators who propose high-impact projects that lead to advances in equity across populations affected by substance use-related harms. Investigators who apply may represent various fields of research, but research projects will emphasize persistent or intractable challenges that drive disparities in medical and other consequences related to substance use and SUD across population groups.

Funding Opportunity RFA-DA-23-029 from the NIH Guide for Grants and Contracts. NEPS Concept # 1862 This concept seeks to support exploratory basic research on interpersonal racism and on parsing the complex effects of structural racism into sub-components and their impact on neurocognition, with an emphasis on informing preventive interventions.

Funding Opportunity RFA-DA-23-028 from the NIH Guide for Grants and Contracts. NEPS Concept # 1862 This concept seeks to support exploratory basic research on interpersonal racism and on parsing the complex effects of structural racism into sub-components and their impact on neurocognition, with an emphasis on informing preventive interventions.

Funding Opportunity RFA-DA-23-026 from the NIH Guide for Grants and Contracts. This initiative invites applications for DP1 awards to support exceptionally creative early career investigators who propose high-impact projects that lead to advances in equity across populations affected by substance use-related harms. Investigators who apply may represent various fields of research, but research projects will emphasize persistent or intractable challenges that drive disparities in medical and other consequences related to substance use and SUD across population groups.

Funding Opportunity RFA-DA-23-025 from the NIH Guide for Grants and Contracts. The purpose of the CED Center is to provide intellectual, technical, and logistic support for the projects. The Center will foster collaboration, support continuous feedback between investigators and communities being served, make shared resources accessible across projects, coordinate initiative workgroups, author original scholarly works and literature for public consumption/lay audiences, facilitate dissemination of findings to promote health in diverse communities.

Funding Opportunity RFA-DA-23-024 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is a part of NIDAs Racial Equity Initiative (REI), a multi-year, multi-pronged effort to eliminate racial inequities in NIDAs workplace, scientific workforce, and research portfolio. The purpose of this initiative is to support pilot or feasibility research on structural factors, organizational practices, policies, and other social, cultural, and contextual influences that lead to inequities at the intersection of HIV and substance use among underserved racial/ethnic populations affected by persistent HIV disparities. Research that addresses the multiple dimensions of individuals identity (e.g., race, ethnicity, gender, sexual orientation, gender identity) and social systems as they intersect with one another is encouraged.

Funding Opportunity RFA-DA-23-023 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is a part of NIDAs Racial Equity Initiative (REI), a multi-year, multi-pronged effort to eliminate racial inequities in NIDAs workplace, scientific workforce, and research portfolio. The purpose of this initiative is to stimulate new observational and intervention research on structural factors, organizational practices, policies, and other social, cultural, and contextual influences that lead to inequities at the intersection of HIV and substance use among underserved racial/ethnic populations affected by persistent HIV disparities. Research that addresses the multiple dimensions of individuals identity (e.g., race, ethnicity, gender, sexual orientation, gender identity) and social systems as they intersect with one another is encouraged.

Funding Opportunity RFA-DA-23-013 from the NIH Guide for Grants and Contracts. NEPS Concept # 1875 This FOA invites R01 applications?to conduct research that will have a major impact in identifying, developing, implementing, or testing strategies to prevent, reduce, or eliminate racial or ethnic disparities in substance use and addiction, thereby advancing health equity. Community engaged research can facilitate rapid advances in this scientific area by ensuring relevant research questions with immediate applicability. As such, applications must be submitted by collaborative community partnered investigative teams who will conduct research projects that address issues prioritized by the community. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in addressing racial or ethnic disparities and inequities in substance misuse. Research areas of interest will reflect community priorities and include etiology, prevention, health services research (including dissemination and implementation research), clinical neuroscience, medical consequences, and treatment and intervention development research.

Notice NOT-GM-22-043 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-011 from the NIH Guide for Grants and Contracts

Notice NOT-DK-22-023 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-NS-22-070 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites research to develop, characterize, and rigorously validate non-rodent mammalian models of pain, associated outcome measures and/or endpoints that enable translational research for effective pain management. These models are expected to recapitulate molecular, cellular, pathological, behavioral, and/or cognitive aspects of human pain disorders and conditions. Research supported under this FOA is expected to provide well-validated models and measures that facilitate the development of non-opioid analgesic therapeutic interventions with little or no addiction liability.

Funding Opportunity RFA-NS-22-062 from the NIH Guide for Grants and Contracts. The purpose of this NINDS-led Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) initiative is to 1) develop tools, standards, and an Open-source software platform that enables a federated (multiple data repository sites with a single access portal) approach for data sharing and analysis of human digital neuropathological slides and 2) perform software testing to validate and verify that the software and tools developed can be used to perform multisite neuropathological analyses using a federated approach. The federated approach requires a single access point of digital slides from multiple geographically distinct brain banks. The resources developed are expected to also enable cross-site annotation and computational image analysis, including advanced analytic approaches. A critical feature of this FOA includes the broad sharing of neuropathological data to further advance research in this area, including the development of a digital resource for distribution and sharing of assessed neuropathological tissue. Software and tools developed under this initiative are expected to be shared using Open Science principles, and the federated digital library is expected to follow FAIR data sharing principles.

Funding Opportunity RFA-AT-23-004 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites applications for REsearch Across Complementary and Integrative Health Institutions (REACH) virtual resource centers. REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions, such as: Schools of acupuncture, chiropractic, osteopathy, naturopathy, physical therapy, and music and art therapy. The REACH virtual resource centers will provide a variety of including, but not limited to Administrative Support, Research Support, Grantsmanship, Mentoring and Training, and Team Building to support clinician scientists located at complementary and integrative health clinical institutions to form multi and interdisciplinary research teams and pursue externally funded research aligned with NCCIH Strategic Priorities for symptom management . REACH centers should focus on resources to support investigators pursuing clinical research (e.g., observational, epidemiological, mechanistic clinical research, mixed methods, feasibility studies, etc). It is expected that REACH virtual resource centers will (1) improve the quality and quantity of federal research grant applications submitted by clinician scientist faculty at complementary and integrative health clinical institutions; (2) aid the formation of multi and interdisciplinary research partnerships across partnering complementary and integrative health clinical institutions; (3) help to enhance the research environment at complementary and integrative health clinical institutions; and (4) support a pipeline for clinician scientists trained in complementary and integrative health practices to pursue research careers at clinical institutions.

Funding Opportunity PA-22-232 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) requests individual Mentored Clinical Scientist Research Career Development (K08) grant applications from applicant organizations. The overall goal of AHRQ- supported career development programs is to help ensure that a diverse pool of highly trained health services researchers is available in adequate numbers and in appropriate research areas to address the mission and priorities of AHRQ.

Funding Opportunity PAR-22-215 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support innovative research that will inform our understanding of the mechanisms underlying the formation of structural birth defects using animal models in conjunction with human translational/clinical approaches. Applicants are encouraged to take advantage of advances in genetics, omics methods (genomics, proteomics, metabolomics, etc.), and synthetic biology, biochemical and other approaches to developmental biology research to identify specific genetic, epigenetic, environmental, or gene/environment interactions associated with the formation of, susceptibility to, and variability of structural birth defects in human populations.

Funding Opportunity PAR-22-223 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support mechanistic studies on host cell death pathways and immune responses to Mycobacterium tuberculosis (Mtb) and Mtb/HIV co-infection to identify immune targets for development of host-directed therapies.

Notice NOT-DA-22-066 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-22-058 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications for the NIAID CDSMC, which will support a broad range of critical support services, including data management and processing, safety and pharmacovigilance management and processing, and sample tracking systems for NIAID-funded clinical trials, integrated studies of underlying mechanisms, clinical studies (e.g., longitudinal studies, genetic studies, etc.), and studies to identify and validate surrogates/biomarkers of immune-mediated diseases in the areas of asthma and allergic diseases, autoimmune diseases, and transplantation.