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Postdoctoral Fellow (Wet Lab) - Pediatric Endocrinology - Medical College of Wisconsin - Milwaukee, WI

Indeed.com - Bioinformatics - Fri, 2022-02-11 04:13
For the other position, we are seeking expertise in bioinformatics and statistics to facilitate analysis of complex scRNAseq, SNP, and Affymetrix gene…
From Medical College of Wisconsin - Fri, 11 Feb 2022 09:13:02 GMT - View all Milwaukee, WI jobs
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NIDCD National Human Ear Resource Network (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-DC-23-002 from the NIH Guide for Grants and Contracts. The objective of this Funding Opportunity Annoucement (FOA) is to fund several laboratories to create a collaborative network, NIDCD National Human Ear Resource Network, to serve as a national technological resource for auditory and vestibular researchers who use human inner and middle ear tissues for a range of basic and clinical studies. The Network will also serve as a nucleus for expanding the use of human temporal bones in the research community and to facilitate communication and collaboration between laboratories, both Network laboratories and non-Network laboratories, using human temporal bones. The Network laboratories will develop and provide technical services for procuring, preparing, sectioning and distributing high-quality human ear tissues; develop and disseminate techniques for improved tissue preservation and processing; and optimize methods for visualizing human middle and inner ear structures, including cellular and membranous components; upload digitized temporal bone images to NIDCD-approved databases for wide dissemination; provide opportunities for technicalinstruction in the special skills needed to ear tissue for use from post-mortem human temporal bones; provide outreach to the scientific and clinical communities to promote the use of human temporal bones in their research and to facilitate the use of resources maintained and developed under this initiative. In addition, applications from individual laboratories may propose research to improve current techniques for the processing and use of human temporal bones. A cooperative agreement will coordinate interactions between the Network laboratories and the research community to maximize impact while avoiding duplicative e?orts. This national resource will benefit a broad spectrum of research projects, including clinical and translational, by providing a critical link towards the translation of animal studies to the human ear and eventually the clinic, supporting the NIDCD mission to

Investigating Transposable Elements and Mobile DNA as Targets of Integration for Establishing HIV Reservoirs in the Brain (R61/R33 - Clinical Trial Optional)

Funding Opportunity RFA-DA-23-003 from the NIH Guide for Grants and Contracts. oMany substances of abuse, including cocaine, methamphetamine, and several opioids exert powerful environmental insults on genomic DNA in the brain that induce expression of transposable elements and other mobile DNA. Transposable elements and mobile DNA, which comprise almost 50% of the human genome, are typically silenced through strong epigenetic modifications. When transposable elements and mobile DNA become active in people who use drugs of abuse, they potentially provide multiple integration sites for HIV in microglia. HIV integration into these unstable regions could lead to major chromosomal rearrangements and global dysregulation of transcription, ultimately contributing to HIV-associated Neurocognitive Disorder (HAND) and providing a mechanism by which drugs of abuse increase the probability of reactivating microglial HIV reservoirs. Understanding the factors that influence HIV integration in these microglial reservoirs is crucial to developing next-generation HIV therapies and potential cures. This concept addresses these gaps by fostering studies aimed at providing a deeper understanding of the complex interplay among HIV, substances of abuse, inflammation, and disease progression.

Guidance on Salary Limitation for Grants and Cooperative Agreements

Notice NOT-OD-22-076 from the NIH Guide for Grants and Contracts

Integrating Mental Health Care into Health Care Systems in Low- and Middle-Income Countries (R01 Clinical Trial Optional)

Funding Opportunity RFA-MH-22-130 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks research project grant (R21 and R01) that explore the utility of established services/platforms structure for treatment of chronic communicable and non-communicable diseases for providing integrated mental health care model / interventions for the treatment of patients with co-morbid mental and chronic conditions in low- and middle-income countries (LMIC). Specifically, this FOA will support research that builds on existing chronic conditions care and treatment platforms to incorporate management of mental illness, employs a multi-disease and multi-levels care management approach with potentially high impact for improving patient- and system-level outcomes, and establishes feasible methods to evaluate and manage multi-disease treatment in LMICs. Findings should have relevance for patients with mental illness across low-resource settings, including in the U.S.

BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed)

Funding Opportunity RFA-NS-22-026 from the NIH Guide for Grants and Contracts. (Reissue of RFA-NS-18-030) This FOA solicits applications for research projects that use innovative, methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior. The goal is to support projects that can realize a meaningful outcome within 5 years. Applications should address circuit function in the context of specific neural systems such as sensation, perception, attention, reasoning, intention, decision-making, emotion, navigation, communication or homeostasis. Projects should link theory and data analysis to experimental design and should produce predictive models as deliverables. Projects should aim to improve the understanding of circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating dynamic patterns of neural activity. Projects can use non-human and human species, and applications should explain how the selected species offers ideal conditions for revealing general principles about the circuit basis of a specific behavior.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences: Project Scientist to join the Superti-Furga Lab at CeMM (m/f/d)

New Scientist - Bioinformatics - Thu, 2022-02-10 12:13
monthly gross salary of at least EUR 3.945,90 (following the recommendations of FWF): CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences: The REsolution consortium is looking for a project scientist to study the functional impact of genetic variations..... Vienna (AT)
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CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences: Project Scientist to join the Superti-Furga Lab at CeMM (m/f/d)

New Scientist - Bioinformatics - Thu, 2022-02-10 12:11
monthly gross salary of at least EUR 3.945,90 (following the recommendations of FWF): CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences: Do you want to be part of a very large multidisciplinary effort committed to understand human membrane..... Vienna (AT)
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BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 Clinical Trials Not Allowed)

Funding Opportunity RFA-NS-22-027 from the NIH Guide for Grants and Contracts. (Reissue of RFA-NS-18-014 and RFA-NS-21-014) This R34 FOA solicits applications that offer a limited scope of aims and an approach that will establish feasibility, validity, or other technically qualifying results that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent Targeted Brain Circuits Projects - TargetedBCP R01, as described in the companion FOA (RFA-NS-22-026). Applications should be exploratory research projects that use innovative, methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior.

EMBL: Scientific Data Software Engineer

New Scientist - Bioinformatics - Thu, 2022-02-10 11:02
Competitive Salary: EMBL: An exciting opportunity has been created for a scientific software engineer to work on the development of the ChEBI database (https://www.ebi.ac.uk/ch Hinxton, Cambridgeshire, England
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EMBL: Bioinformatics Systems Engineer

New Scientist - Bioinformatics - Thu, 2022-02-10 11:00
Competitive Salary: EMBL: We are looking for an innovative technical engineer who can help develop and deploy the workflow and data infrastructure that is becoming increasingly Hinxton, Cambridgeshire, England
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Limited Competition: NIH Neuroscience Doctoral Readiness Program (DR. Program) (R25 Clinical Trial Not Allowed)

Funding Opportunity RFA-NS-22-035 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) provides support to eligible, domestic institutions to develop and implement effective, approaches to biomedical research education and mentoring that will keep pace with the rapid evolution of the research enterprise. This NIH Neuroscience Doctoral Readiness Program (DR Program) expects that the proposed research education programs will incorporate extensive research experiences within the NINDS mission and well-designed courses for skills development and education to prepare recent baccalaureates from diverse backgrounds to transition into and complete rigorous, research-focused doctoral degree programs (e.g., Ph.D. or M.D./Ph.D.) in biomedical fields. This is a limited competition funding opportunity announcement to support postbaccalaureate programs that will be affiliated with a funded NIH T32 program. Eligibility is limited to PD(s)/PI(s) or MPI teams that include at least one PD/PI of a grant supported by the following FOAs: T32 - Jointly Sponsored Institutional Predoctoral Training Program (JSPTPN), PAR-20-076;NINDS T32 - Institutional Research Training Grant, PAR-21-149; or NINDS T32 - Institutional Translational Research Training Program, PAR-19-228. In all cases, a PD/PI of the T32 grant from a FOA cited above, must be the PD/PI or an MPI of this R25. This Funding Opportunity Announcement (FOA) does not allow appointed participants to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Data, Evaluation and Coordinating Center for: A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials (CUSP2CT) (U24 Clinical Trial Not Allowed)

Funding Opportunity RFA-CA-22-014 from the NIH Guide for Grants and Contracts. The purpose of this solicitation is to fund a Data, Evaluation and Coordinating Center (DECC) that will support the data and evaluation activities and coordinate a learning collaborative related to the CUSP2CT program (companion RFA CA-21-057).

Notice of NIH Participation in the National Robotics Initiative (NRI)

Notice NOT-EB-22-003 from the NIH Guide for Grants and Contracts

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