Funding Opportunity PAR-21-335 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma. The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying those patients at high risk of PDAC (because of genetic factors or presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; determine which pancreatic cysts are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens and data within the Consortium. The other scientific component of the PCDC will be the Management and Data Coordination Unit (MDCU). The PCDC-MDCU will provide support toward study design, protocol development, statistical analysis, coordination, harmonization, data management and stewardship for the trans-PCDC collaborative projects, including biorepository building effort.

Funding Opportunity PAR-21-334 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma. The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying those patients at high risk of PDAC (because of genetic factors or presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; determine which pancreatic cysts are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens and data within the Consortium. The other scientific component of the PCDC will be the Management and Data Coordination Unit (MDCU). The PCDC-MDCU will provide support toward study design, protocol development, statistical analysis, coordination, harmonization, data management and stewardship for the trans-PCDC collaborative projects, including biorepository building effort. The PCDC-MDCU will also supp

Competitive with benefits, subject to skills & experience: The Francis Crick Institute: The Postdoctoral Research Assistant will contribute to a mechanistic understanding of autophagosome initiation. London (Central), London (Greater) (GB)

Notice NOT-EB-21-026 from the NIH Guide for Grants and Contracts

Earned doctorate (or its foreign equivalent) or appropriate terminal degree. Experience in microbial ecology, molecular methods and/or bioinformatics to…
From Marquette University - Wed, 15 Sep 2021 16:22:18 GMT - View all Milwaukee, WI jobs

£73,784-£86,736: Wellcome Sanger Institute: Do you have excellent knowledge of health data and informatics and would like to make a difference to national health research? The Opportunity: He... Hinxton, Cambridgeshire

Funding Opportunity PAR-21-325 from the NIH Guide for Grants and Contracts. Reissue of PAR-18-894: The purpose of this Funding Opportunity Announcement (FOA) is to enhance the diversity of the mental health research workforce by providing dissertation awards in all research areas within the strategic priorities of the NIMH to individuals from backgrounds underrepresented in biomedical, behavioral, clinical and social sciences research. This award supports the completion of the doctoral research project.

Our technology can be used to create induced pluripotent stem cells (iPSCs) from anyone and followed by the powerful capability to develop into virtually any…
From Cellular Dynamics - Wed, 15 Sep 2021 05:37:32 GMT - View all Madison, WI jobs

£27,788-£33,288: Wellcome Sanger Institute: The Opportunity: We are seeking an enthusiastic and motivated research assistant to provide experimental, scientific and operational support to the... Hinxton, Cambridgeshire

Notice NOT-DA-21-082 from the NIH Guide for Grants and Contracts

Notice NOT-CA-21-117 from the NIH Guide for Grants and Contracts

Notice NOT-DA-21-081 from the NIH Guide for Grants and Contracts

Notice NOT-NS-22-026 from the NIH Guide for Grants and Contracts

Adapts bioinformatics tools, visualization packages, and annotation resources for research projects to independently and accurately perform research analysis.
From Medical College of Wisconsin - Tue, 14 Sep 2021 09:10:02 GMT - View all Menomonee Falls, WI jobs

Notice NOT-DA-21-074 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-RM-21-026 from the NIH Guide for Grants and Contracts. This FOA seeks to support state-of-the-art Tissue Mapping Centers (TMCs) that will serve as the core data generators for the HuBMAP Consortium by generating a high-resolution, multi-parameter, 3D atlas of a non-diseased human organ. Successful centers will build, benchmark, and standardize pipelines for generating, validating and analyzing data from multiplexed, high-throughput imaging and omics technologies. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation in order to build high-resolution maps. Centers will use these maps to provide new insights into intra-, inter- and extra- cellular organizational features that influence tissue function, vary across individuals or that change across the lifespan. By the end of four years of funding, a successful center will have created a significant number of high-resolution, multi-scale, multi-dimensional molecular, cellular and morphological maps from multiple donors that are integrated into a published reference atlas for that organ.

£32,780-£41,093: Wellcome Sanger Institute: We have an opportunity for a postdoctoral fellow to join us under the leadership of Dr Ana Cvejic (University of Cambridge) and Peter Campbell (Wel... Cambridgeshire (GB)

Salary between £38,000-£45,000 per annum inclusive, subject to skills & experience: The Francis Crick Institute: This position will be part of an already existing Core team of 14 providing bioinformatics expertise to the Crick scientists. London (Greater) (GB)

D. E. Shaw Research is seeking Ph.D.–level scientists to join our New York–based team.  This is a unique opportunity to develop and work with transformative

Funding Opportunity PAR-21-319 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages exploratory/developmental research grant applications, proposing the development of innovative, collaborative research projects on brain and other nervous system function and disorders throughout life, relevant to low- and middle-income countries (LMICs). Research on neurological, mental, behavioral, alcohol and substance use disorders may span the full range of science from basic to implementation research. Scientists in the United States (U.S.) or upper-middle income countries (UMICs) are eligible to partner with scientists in LMIC institutions. Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories used are as defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups. These grants are expected to foster the development of more comprehensive research programs that contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, prevention, treatment and implementation strategies. The proposed work may also contribute to developing a base for research networking and evidence-based policy beyond the specific research project.