GBP45000.00 - GBP50000.00 per annum: SRG: Head of Training and Quality Cambridge, England

Funding Opportunity PAR-22-024 from the NIH Guide for Grants and Contracts. This FOA invites investigation of biological and clinical measures of TBI-related progressive neurodegeneration and neurocognitive decline associated with increased risk for dementia and /or traumatic encephalopathy syndrome (TES) (clinicopathologic diagnostic counterpart to the neuropathological diagnosis of Chronic Traumatic Encephalopathy (CTE)). Investigations should be based on existing, well-characterized populations of patients with a history of TBI that are enriched for increased risk of cognitive impairment or dementia and can continue to be followed longitudinally; additional subjects may be recruited as appropriate. The overall goal is to advance knowledge of the underlying pathophysiology and clinical characterization of the chronic effects of TBI that distinguish static-chronic TBI cognitive impairment from those that lead to progressive neurodegeneration associated with TES and dementia. A critical feature of this FOA includes the broad sharing of clinical, neuroimaging, physiological, and biospecimen data and to create a data and associated biofluid resource for the broader community to further advance research in this area.

Bioinformatics approaches for analysis of data sets. Experience with molecular methods including nucleic acid extraction, purification, PCR design and next…
From University of Wisconsin–Madison - Tue, 10 Aug 2021 00:58:12 GMT - View all Madison, WI jobs

In this installment of Your Unicorn Career, our columnist advises about guarding your career against attacks from within

GBP39748.0 - GBP44166.0 per annum: Science and Technology Facilities Council (STFC): HNCDI Computational Biologist/Bioinformatician £39,748 - £44,166 Gross per AnnumScience and Technology Facilities Council (STFC), UKRIDo you pride yo Warrington, England

Funding Opportunity RFA-MD-21-003 from the NIH Guide for Grants and Contracts. This initiative will support a single resource center to provide focused technical assistance and support to Tribal Epidemiology Centers (TECs) to enhance the research and data science capacity for health research focused on American Indian/Alaska Native (AI/AN) populations.

Notice NOT-OD-21-172 from the NIH Guide for Grants and Contracts

£32,780-£41,093: Wellcome Sanger Institute: The Opportunity: The Bentley team is seeking an enthusiastic and self-motivated Postdoctoral Fellow to contribute to the group’s pathogen genomics ... Cambridge, Cambridgeshire (GB)

Funding Opportunity PAR-22-023 from the NIH Guide for Grants and Contracts. Recent findings have raised the hypothesis that systemic immune responses could play direct or indirect roles in brain neurodegeneration leading to AD/ADRD, and has been significantly less studied compared to innate immune mechanisms such as microglia in the brain. This initiative will capitalize on growing interest in the research community and will support partnerships and new collaborations between neuroscientists and immunologists to expand the research base in this area with the long-term goal of bringing more immunology expertise into the AD/ADRD field. This is a new initiative seeking research into the role of systemic immune responses and inflammation in AD/ADRD. Individual projects are sought and collaborations between neuroscientists with expertise in AD/ADRDs and immunologists will be highly encouraged. Through these awards, a more solid research base in this area will be established that can support further work in this area through investigator-initiated and other mechanisms.

Funding Opportunity RFA-HG-21-029 from the NIH Guide for Grants and Contracts. This FOA is one of three issued to create a new program called "Molecular Phenotypes of Null Alleles in Cells (MorPhiC)". The long-term goal of MorPhiC is to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene, using in vitro multicellular systems. The catalog will be made available for broad use by the biomedical community. The program will start with a Phase 1 to optimize available methods to create null alleles and measure their phenotypic effects in a target subset of 1000 protein coding genes across the program. Phase I will also assess the scale limitations of such methods, develop common data formats, and establish use cases for this catalog. This specific FOA seeks applications for MorPhiC Data Production Research and Development Centers, which will develop diverse systems and assays and explore and compare approaches to produce MorPhiC data at scale, and to maximize its informativeness.

Funding Opportunity RFA-HG-21-031 from the NIH Guide for Grants and Contracts. This FOA is one of three issued to create a new program called "Molecular Phenotypes of Null Alleles in Cells (MorPhiC)". The long-term goal of MorPhiC is to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene, using in vitro multicellular systems. The catalog will be made available for broad use by the biomedical community. The program will start with a Phase 1 to optimize available methods to create null alleles and measure their phenotypic effects in a target subset of 1000 protein coding genes across the program. Phase I will also assess the scale limitations of such methods, develop common data formats, and establish use cases for this catalog. This specific FOA seeks applications for MorPhiC Data Analysis and Validation Centers. These Centers will develop computational models and data analysis and visualization methods to evaluate and help ensure the utility of the MorPhiC data. Separate FOAs will be issued for the two other components of MorPhiC: Data Production Research and Development Centers and a Data Resource and Administrative Coordination Center to receive, annotate, and present data for consortium and public use and to be the administrative coordinating center for the MorPhiC consortium.

Funding Opportunity RFA-HG-21-030 from the NIH Guide for Grants and Contracts. This FOA is one of three issued to create a new program called "Molecular Phenotypes of Null Alleles in Cells (MorPhiC)". The long-term goal of MorPhiC is to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene, using in vitro multicellular systems. The catalog will be made available for broad use by the biomedical community. The program will start with a Phase 1 to optimize available methods to create null alleles and measure their phenotypic effects in a target subset of 1000 protein coding genes across the program. Phase I will also assess the scale limitations of such methods, develop common data formats, and establish use cases for this catalog. This specific FOA seeks applications for MorPhiC Data Analysis and Validation Centers. These Centers will develop computational models and data analysis and visualization methods to evaluate and help ensure the utility of the MorPhiC data. Separate FOAs will be issued for the two other components of MorPhiC: Data Production Research and Development Centers and a Data Resource and Administrative Coordination Center to receive, annotate, and present data for consortium and public use and to be the administrative coordinating center for the MorPhiC consortium.

Funding Opportunity RFA-NS-22-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support hypothesis-driven clinical research applications that are focused on discovering novel diagnostic, prognostic, and/or therapeutic biomarkers for the Lewy Body Dementias (LBD).Biomarker research must be conducted in patients with LBD, must follow Parkinson's Disease Biomarker Program (PDBP) protocols for clinical assessment and biospecimen collection,and must be broadly shareable through the PDBP repositories.

Notice NOT-AI-21-067 from the NIH Guide for Grants and Contracts

Notice NOT-DK-21-024 from the NIH Guide for Grants and Contracts

Notice NOT-DE-21-010 from the NIH Guide for Grants and Contracts

Adapts bioinformatics tools, visualization packages, and annotation resources for research projects to independently and accurately perform research analysis –…
From Medical College of Wisconsin - Fri, 06 Aug 2021 03:09:15 GMT - View all Milwaukee, WI jobs

Funding Opportunity PAR-21-304 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support a Brazil-US Regional Prospective Observational Research in Tuberculosis (RePORT) network that will leverage the robust clinical research infrastructure of Brazil to advance our current understanding of the community, host and microbial factors that impact outcomes of tuberculosis (TB) infection and TB disease, especially among persons with HIV (PWH), including drug-resistant TB, to facilitate development of tools to improve treatment outcomes at the individual level and to inform strategies to curtail the TB epidemic at the public health level.

Competitive Salary: EMBL: We are seeking a Full Stack Software Engineer with preferably a background in bioinformatics to join the Data Coordination and Archiving (DCA) Team at Hinxton, Cambridgeshire, England

Notice NOT-AG-21-032 from the NIH Guide for Grants and Contracts