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White Matter Lesion Etiology of Dementia in the U.S. Including in Health Disparity Populations (U19 Clinical Trial not Allowed)

Funding Opportunity RFA-NS-20-013 from the NIH Guide for Grants and Contracts. Despite established associations between white matter lesions and cognitive impairment including dementia, the volume, anatomical location, and other key cellular and molecular characteristics of white matter lesions that are both necessary and sufficient are unknown, as are the comorbid clinical factors that may modify (including protect from) these effects. Therefore, this initiative will support one large prospective clinical research study in the U.S. studying individuals with white matter lesions at risk for cognitive decline to determine the magnitude and anatomical locations that are both necessary and sufficient to cause cognitive impairment and dementia. The study will include health disparities populations, and will examine additional clinical factors and comorbidities that may be effect modifiers of the relationship between white matter lesions and cognitive impairment, including dementia. Clinical trial-ready VCID biomarkers should be utilized, further developed, and/or subject to implementation research in this study. Secondary goals include: identifying clinical and mechanistic targets for future VCID interventional trials; determining interrelationships (cross-sectional and longitudinal) among white matter lesions, cerebro- and cardio-vascular disease and risk factors including dementia-relevant genes. Applicants are encouraged, when scientifically advantageous, to utilize existing resources for VCID and stroke research, e.g. MarkVCID, StrokeNet, Alzheimers Centers, and large NIH funded prospective cohort studies (e.g. Framingham, ARIC, CHS, NOMAS, etc.) as well as other dementia resources.

Bioinformatics Manager - Medical College of Wisconsin - Milwaukee, WI

Indeed.com - Bioinformatics - Thu, 2019-12-26 16:08
Leads the BDAU team in, or, if necessary, directly performs bioinformatics analysis on research or clinical samples to meet deadlines defined in SoW.
From Medical College of Wisconsin - Thu, 26 Dec 2019 21:08:44 GMT - View all Milwaukee, WI jobs
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Methods and Measurement in Research with Sexual and Gender Minority (SGM) Populations (R21- Clinical Trials Not Allowed)

Funding Opportunity RFA-MD-20-005 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support projects to advance the measurement of constructs relevant to health research with sexual and gender minority (SGM) populations.

Instructor, Biology - Laramie County Community College - Cheyenne, WY

Indeed.com - Bioinformatics - Fri, 2019-12-20 19:37
One year of experience with specialized instrumentation and techniques (microscopy, bioinformatics, statistics, etc.). This is a 9-Month, Faculty 5 position. $51,373 - $61,647 a year
From Laramie County Community College - Sat, 21 Dec 2019 00:37:43 GMT - View all Cheyenne, WY jobs
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Wellcome Sanger Institute: Senior Research Assistant

New Scientist - Bioinformatics - Fri, 2019-12-20 13:25
£34,546-£41,801: Wellcome Sanger Institute: Senior Research Assistant #{%22news%22:{}}">Genome Wellcome Campus. We hold an Athena SWAN Bronze Award and will consider all individuals without Hinxton, Cambridgeshire, England
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SRG: Bioinformatics Scientist

New Scientist - Bioinformatics - Fri, 2019-12-20 12:02
Negotiable: SRG: Biotech based in the Cambridge area is an innovative company working in diagnostic development is looking for an experienced data analysis scientist. Cambridge, England
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Astex Pharmaceuticals: Structural Bioinformatics Scientist

New Scientist - Bioinformatics - Fri, 2019-12-20 06:46
Competitive: Astex Pharmaceuticals: Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company Cambridge, Cambridgeshire
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