Notice NOT-AR-24-008 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DK-23-001 from the NIH Guide for Grants and Contracts. Parkinsons disease (PD) is the second most common and fastest growing neurodegenerative disorder, with approximately 60,000 Americans diagnosed annually. PD symptoms are not limited to motor dysfunction and more than 50% of patients who develop PD often have a history of bowel complaints affecting nearly all parts of the gastrointestinal (GI) system. These SI symptoms often precede the onset of motor symptoms, indicating that GI dysfunction may be an early manifestation of the disease and the gut may be an unexplored diagnostic and/or therapeutic target. The purpose of this Funding Opportunity Announcement (FOA) is to establish a Gut Brain Parkinson's Diesase Consortium (GBPDC) The Data Coordinating Center (DCC) of the GBPDC will coordinate collaboration among the Gastroenterology Neurology Research Centers (GNRCs, as described in the companion FOA, RFA-DK-22-036), enrollment of subjects into the study, submission of data and other biological samples to central repositories, processing of biospeciments, submission of clinical, cellular and molecular data to central databases, and data analysis. The DCC will manage the operations of the GBPDC Steering Committee and other operational committees and provide the infrastructure for the efficient design and conduct of multicenter clinical studies and establishe a repostiory of patient samples that may be used for ancillary studies of etiology and pathogenesis. The DCC will also coordinate the development of pilot projects for rapid follow-up of emerging findings by members of the GBPDC.

Funding Opportunity RFA-DK-22-036 from the NIH Guide for Grants and Contracts. This FOA invites new applications to participate in the Gut-Brain Communication in Parkinsons Disease (PD) Consortium (GBPDC). The goals of this initiative are 1) to establish a network of individual research projects and a Coordinating Center focused on clinical research; 2) recruitment of sufficient patients and use of standardized protocols to collect data and biospecimens relevant to both neurology and gastroenterology research on PD; 3) share data, biomaterials, models, reagents, resources and methods among projects in the GBPD; and 4) make these publicly available through the Coordinating Center. The objective of this consortium is to accelerate research on the role gastrointestinal (GI) symptoms and changes in gut-brain communication in the initiation and pathogenesis of Parkinsons disease in order to facilitate development and validation of innovative early-phase GI-based diagnostic tools and biomarkers for PD. The research centers of the GBPDC will serve as sites for enrollment of PD patients with and without GI symptoms, patients with GI symptoms considered to be at risk for PD, and healthy age-matched controls for laboratory-based studies on biological samples obtained from these patients. The NIDDK strongly encourages Research on Sex/Gender Differences, Sexual and Gender Minority-Related Research and Race/Ethnic Diversity (see NOT-DK-22-003).

Notice NOT-OD-23-161 from the NIH Guide for Grants and Contracts

Notice NOT-HG-23-047 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-045 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-101 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-235 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications for Biomedical Technology Resource Centers (BTRCs). BTRCs are national resource centers for conducting research and development on new technologies that are driven by the needs of basic, translational, and/or clinical researchers. BTRCs also make their technologies available to other investigators, train members of the research community in the use of the technologies, and disseminate the technologies broadly.

Notice NOT-NR-23-014 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-OD-23-021 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications for a Research Project Grant (U01) that will utilize health communication research to better understand the impact that messaging about the continuum of risk for tobacco products may have on various segments of the population. The NIH and the FDA have formed an interagency partnership to foster research relevant to tobacco regulatory science within the framework of the Family Smoking Prevention and Tobacco Control Act (FSPTCA). The award under this NOFO will be administered by NIH using designated funds from the FDA Center for Tobacco Products (CTP) for tobacco regulatory science mandated by the FSPTCA. Funds for this program have been made available through the FSPTCA (P.L. 111-31).

Notice NOT-HS-23-018 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-078 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-058 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-098 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-080 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-RM-23-015 from the NIH Guide for Grants and Contracts. Many valuable and widely available data sets have been generated by multiple Common Fund programs. The purpose of this NOFO is to announce the availability of funding to demonstrate and enhance the utility of selected Common Fund data sets, including generating hypotheses and catalyzing discoveries. Award recipients are also asked to provide feedback on the utility of the Common Fund data resources.

Funding Opportunity RFA-AG-24-044 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications for pharmacokinetic and pharmacodynamic (PK/PD) studies of mTOR inhibitors inpopulations living with different aging-related diseases or in relatively healthy older adult populations at risk for a variety of aging conditions. The studies will be funded by individual awards but will be required to interact as a network to exchange information, possibly develop harmonized measures, and pool data to facilitate broader assessment of the effects on multiple aging-related outcomes and mechanisms affected by mTOR modulation.

Notice NOT-AA-23-015 from the NIH Guide for Grants and Contracts

Notice NOT-EB-23-005 from the NIH Guide for Grants and Contracts

Notice NOT-AA-23-016 from the NIH Guide for Grants and Contracts