NIH Funding Opportunities (Notices, PA, RFA)

Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 2 hours 8 min ago
Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
Funding Opportunity PAR-23-157 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This FOA is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional)
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Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Basic Experimental Studies with Humans (BESH) Required)
Funding Opportunity PAR-23-158 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award activity code to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This NOFO is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional).
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Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-171 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to provide investigators with access to resources provided by the Data Management Coordinating Center for Diagnostic Centers of Excellence (RFA-NS-22-051), as part of the next phase of the Undiagnosed Diseases Network. Resources include infrastructure, data management, and clinical research support for a new Network of clinical sites that provide diagnostic services for patients with undiagnosed diseases.
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Notice of Change to Application and Submission Information in RFA-AI-22-076, Consortium for Food Allergy Research: Clinical Research Center (U01 Clinical Trial Required)
Notice NOT-AI-23-043 from the NIH Guide for Grants and Contracts
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Developing Measures to Advance Quality in Mental Health Care Services (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-23-265 from the NIH Guide for Grants and Contracts. This RFA aims to support the development, testing, validation and implementation of quality metrics in mental health services research, that can be submitted to and endorsed by the relevant regulatory or governing bodies. In order to support the implementation and dissemination of high-quality mental health services, effective measures of defining and assessing quality are needed. Very few measures exist for assessing the quality of mental health care services; as noted by the Agency for Healthcare Research and Quality (AHRQ), these measures are not typically standardized or utilized uniformly. These quality measures can be used by policymakers, payers, organizational leaders, and clinicians for a variety of endeavors, including providing measurement-based care, evaluating the effectiveness of evidence-based care, enacting quality improvement interventions, assessing comparative- and cost-effectiveness across programs or clinical settings, utilizing real-world data in decision-making, and developing payment models, in order to continually improve mental health functioning and outcomes.
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Fundamental Research to Understand the Mechanisms of Neurotropic Virus-mediated Disease (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-23-028 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote basic research to better understand the mechanisms underlying viral invasion of the central nervous system (CNS), virus- and/or host immune-mediated neuropathogenesis, and the associated clinical manifestations for emerging and re-emerging neurotropic viruses.
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Notice of Correction to Section IV. Application and Submission Information for RFA-NS-24-022 "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRCs) (U54 Clinical Trial Optional)"
Notice NOT-NS-23-083 from the NIH Guide for Grants and Contracts
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Understanding Persistent Oral Human Papillomavirus and Human Immunodeficiency Virus Co-infection and Its Role with Oropharyngeal Cancer Induction (R21 Clinical Trial Not Allowed)
Funding Opportunity RFA-DE-24-002 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit developmental/exploratory research to better understand the mechanisms of persistent oral human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection as well as its role in the induction and pathogenesis of HPV-associated oropharyngeal cancers (HPV-OPC).
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Understanding Persistent Oral Human Papillomavirus and Human Immunodeficiency Virus Co-infection and Its Role with Oropharyngeal Cancer Induction (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DE-24-001 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit research to better understand the mechanisms of persistent oral human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection as well as its role in the induction and pathogenesis of HPV-associated oropharyngeal cancers (HPV-OPC).
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Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)
Funding Opportunity PAR-23-164 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain and the incorporation of, pilot or clinical feasibility evaluation from previously collected data in pre-clinical studies. These studies are expected to provide the requisite data needed to advance promising PET ligands for use in clinical research.
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Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-165 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research grant applications that propose the preclinical development of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in rodent and nonhuman primate brain and incorporation of pilot or clinical feasibility evaluation in pre-clinical studies and appropriate model development. Projects proposing clinical assessments of novel radioligands should respond to FOA PAR XX-XXX .
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Notice of NIDCD Participation in PAR-21-251 "Emerging Global Leader Award (K43 Independent Clinical Trial Required)" and PAR-21-252 Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
Notice NOT-DC-23-007 from the NIH Guide for Grants and Contracts
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Notice of Change to Funding Opportunity Implementing and Evaluating New Models for Delivering Comprehensive, Coordinated, Person-Centered Care to People with Long COVID (U18)
Notice NOT-HS-23-010 from the NIH Guide for Grants and Contracts
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Notice of Clarification to Eligibility Criteria for PAR-22-265 "Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)"
Notice NOT-NS-23-080 from the NIH Guide for Grants and Contracts
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Notice to Extend the Expiration Date of RFA-HG-22-004: Genome Research Experiences to Attract Talented Undergraduates into Genomic Fields to Enhance Diversity (R25 Clinical Trial Not Allowed)
Notice NOT-HG-23-031 from the NIH Guide for Grants and Contracts
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Implementation Science for Cancer Control in People Living with HIV in Low- and Middle-Income Countries (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-23-033 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support Implementation Science for Cancer Control in People Living with HIV (PLWH) in Low- and Middle-Income Countries (LMICs) to accelerate the integration of evidence-based cancer control interventions for PLWH by leveraging existing HIV treatment and prevention infrastructure. Specifically, this FOA solicits applications that will identify, understand, and develop strategies to address barriers to the adoption, integration, and sustainability of evidence-based cancer control interventions among PLWH in LMICs and generate data in LMICs that can inform effective and equitable implementation of evidence-based cancer control for PLWH worldwide. Responsive applications should include multi-disciplinary teams of researchers with expertise in HIV, cancer, and implementation science to address the cancer control needs of PLWH populations specific to the proposed LMIC context.
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Core Centers for Clinical Research (CCCR) (P30 Clinical Trial Not Allowed)
Funding Opportunity RFA-AR-24-003 from the NIH Guide for Grants and Contracts. Core Centers for Clinical Research (CCCR) (P30 Clinical Trial Not Allowed)
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Request for Information (RFI) on the NIH Office of Disease Prevention Strategic Plan for Fiscal Years 20242028
Notice NOT-OD-23-108 from the NIH Guide for Grants and Contracts
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Enhancing Science, Technology, EnginEering, and Math Educational Diversity (ESTEEMED) Research Education Experiences (R25 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-114 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on:Courses for Skills DevelopmentResearch Experiences
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NHLBI Notice of Availability of Frequently Asked Questions (FAQs) for NOT-HL-23-078 and NOT-HL-23-079 (CAROL Act)
Notice NOT-HL-23-085 from the NIH Guide for Grants and Contracts
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