NIH Funding Opportunities (Notices, PA, RFA)

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 2 hours 19 min ago

HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)

Tue, 2022-02-08 10:20
Funding Opportunity RFA-NS-22-050 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery of strong candidate biomarkers or biomarker signatures for pain that can be used to facilitate the testing of non-opioid pain therapeutics in Phase II clinical trials.The biomarkers or biomarker signature will be developed through clinical research specifically focused on the identification of pain biomarkers or biosignatures that predict and/or monitor response to pain therapeutics. The resulting biomarkers or biomarker signatures may be focused on a single pain condition or on several pain conditions with common underlying pathophysiology. Applications to identify biomarkers or biomarker signatures that predict or monitor a therapeutic response across several related pain conditions should feature Multiple Principal Investigator (MPI)-led teams that represent each of the related pain conditions and associated clinical networks. The MPI-led teams are expected to decide upon a single set of measures or biomarker modalities (i.e., combination of omics, QST, actigraphy, EEG, digital measures, etc.) as components of the biosignature for all pain conditions represented in the application. Applications should feature centralized resource groups that will coordinate clinical trials and standardize all sample or data collection methods, technology development, statistical analysis and algorithm development across the pain conditions under investigation. Applications seeking to develop biomarkers or biomarker signatures that will be used to predict and/or monitor a therapeutic response for a single pain condition must also feature MPI-led teams that represent the cross functional expertise necessary for biomarker and/or signature development, along with the same types of centralized resource groups that coordinate clinical trials and standardize sample or data collection methods, technology development and statistical analysis.

Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services

Tue, 2022-02-08 10:03
Notice NOT-MH-22-110 from the NIH Guide for Grants and Contracts

Notice of Special Interest (NOSI): Assessment of Suicide Thoughts and Behaviors among Children and Preteens

Tue, 2022-02-08 02:33
Notice NOT-MH-22-086 from the NIH Guide for Grants and Contracts

Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional)

Tue, 2022-02-08 02:31
Funding Opportunity PAR-22-098 from the NIH Guide for Grants and Contracts. This is a reissue to correct a few errors and omissions. This Funding Opportunity Announcement (FOA) encourages exploratory/developmental research grant applications, proposing the development of innovative, collaborative research projects on brain and other nervous system function and disorders throughout life, relevant to low- and middle-income countries (LMICs). Research on neurological, mental, behavioral, alcohol and substance use disorders may span the full range of science from basic to implementation research. Scientists in the United States (U.S.) or upper-middle income countries (UMICs) are eligible to partner with scientists in LMIC institutions. Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories used are as defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups. These grants are expected to foster the development of more comprehensive research programs that contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, prevention, treatment and implementation strategies. The proposed work may also contribute to developing a base for research networking and evidence-based policy beyond the specific research project.

Notice of Correction to PAR-21-237 "NINDS Efficacy Clinical Trials (UG3/UH3 Clinical Trial Required)"

Tue, 2022-02-08 02:29
Notice NOT-NS-22-060 from the NIH Guide for Grants and Contracts

Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional)

Tue, 2022-02-08 02:29
Funding Opportunity PAR-22-097 from the NIH Guide for Grants and Contracts. This is a reissue to correct errors and omissions. This Funding Opportunity Announcement (FOA) encourages grant applications for the conduct of innovative, collaborative research projects between U.S. and low- and middle-income country (LMIC) scientists, on brain and other nervous system function and disorders throughout life, relevant to LMICs (including neurological, mental, behavioral, alcohol and substance use disorders and spanning the full range of science from basic to implementation research). Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories are defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups.

Notice of Change to Application Due Dates for RFA-MH-22-175

Tue, 2022-02-08 02:24
Notice NOT-MH-22-160 from the NIH Guide for Grants and Contracts

Notice of Change to Application Due Dates for RFA-MH-22-176

Tue, 2022-02-08 02:20
Notice NOT-MH-22-161 from the NIH Guide for Grants and Contracts

Request for Information (RFI): Priorities for Cancer Control and Population Sciences at NCI

Tue, 2022-02-08 02:05
Notice NOT-CA-22-055 from the NIH Guide for Grants and Contracts

Request for Information (RFI): Priorities for Cancer Control and Population Sciences at NCI

Tue, 2022-02-08 02:04
Notice NOT-CA-22-053 from the NIH Guide for Grants and Contracts

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