Notice NOT-HG-24-052 from the NIH Guide for Grants and Contracts

Notice NOT-HD-24-029 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-059 from the NIH Guide for Grants and Contracts

Notice NOT-HD-24-033 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-24-065 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support milestone-driven, early-stage translational research focused on drug discovery and development of novel therapeutics against select fungal pathogens including: Candida species, specifically Candida auris; Aspergillus fumigatus; Coccidioides; and Mucorales. This NOFO will use a milestone-driven, biphasic award mechanism. Transition to the R33 phase will depend on the successful completion of specific milestones during the R21 phase.

Notice NOT-OD-24-176 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-175 from the NIH Guide for Grants and Contracts

Notice NOT-HD-24-030 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-MH-25-200 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to seek Program Project (P01) applications from scientific hubs to support learning health care research in clinics offering evidence-based Coordinated Specialty Care (CSC) to persons in the early stages of psychotic illness. For this NOFO, early psychosis is defined as the period spanning the onset of an affective or non-affective psychotic disorder and up to 5 years following the first episode of psychosis. Each scientific hub will link multiple early psychosis service programs through (1) the EPINET Core Assessment Battery (CAB) of early psychosis clinical features, CSC services, and treatment outcomes; (2) informatics tools to collect de-identified, person-level data across sites; and (3) a unified approach for analyzing pooled data and disseminating promising findings rapidly across the network.

Funding Opportunity RFA-NS-25-023 from the NIH Guide for Grants and Contracts. This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).

Notice NOT-OD-24-174 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-173 from the NIH Guide for Grants and Contracts

Notice NOT-HS-24-025 from the NIH Guide for Grants and Contracts

Notice NOT-DK-24-037 from the NIH Guide for Grants and Contracts

Notice NOT-DA-26-004 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-24-023 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support research projects under Phase 3 of the U.S.-South Africa Program for Collaborative Biomedical Research. Research areas supported under this program include HIV/AIDS, HIV/AIDS co-morbidities and co-infections, HIV/AIDS-associated implementation science, and HIV/AIDS-associated data science. The hallmark of the U.S.-South Africa program is the development of collaborative partnerships between South African investigators and United States (U.S.) investigators. Through international collaboration, this research will advance scientific discoveries, promote sharing of technologies and approaches, and serve local public health needs and priorities in support of global HIV/AIDS research.

Funding Opportunity PAR-24-297 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigators to the area of brain imaging research. This NOFO will support both newly independent investigators and established investigators who are seeking to develop and adopt neuroimaging tools and methodologies in their research programs and conduct small "proof-of-concept" studies relevant to substance use disorders and addiction. This NOFO is intended to support Small Research Grant (R03) projects that can be carried out in a short period of time with limited resources.

Notice NOT-HD-24-032 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DK-25-021 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications that are focused on developing, using, and/or improving cellular models that recapitulate critical aspects of normal human physiology, such as microphysiological systems, organoids, and other three-dimensional models, to explore the interaction of HIV with tissues and processes within NIDDK's mission areas. Projects are expected to investigate mechanisms of viral persistence, latency, reactivation, eradication, or pathological processes contributing to co-occurring conditions.

Notice NOT-GM-24-058 from the NIH Guide for Grants and Contracts