Funding Opportunity PAR-18-909 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits pre-applications for projects that test new therapeutic uses for experimental drugs or biologics (Assets) across a broad range of human diseases in adult and pediatric populations. This innovative program allows investigators to propose new therapeutic uses for Assets from pharmaceutical company partners. Strong applications will include scientific evidence that modulation of an Assets target will have a positive impact on the disease/condition.

Funding Opportunity RFA-ES-18-007 from the NIH Guide for Grants and Contracts. The purpose of the updated ViCTER program is to use the R01 mechanism to foster and promote early-stage transdisciplinary collaborations and/or translational research efforts among fundamental (technology and mechanism oriented), clinical (patient-oriented) and population-based researchers in the environmental health field. The newly established collaborative teams will come together in common interest to investigate potential linkages between human health and one or more environmental stressor(s). The ViCTER program is intended to support innovative high-risk, high-reward cross-disciplinary and/or translational research projects that are more difficult to achieve in a typical R01 application. Collaboration among investigators at different institutions through a virtual consortium arrangement are encouraged.

Notice NOT-HG-18-015 from the NIH Guide for Grants and Contracts

Notice NOT-MH-18-047 from the NIH Guide for Grants and Contracts

Notice NOT-MH-18-046 from the NIH Guide for Grants and Contracts

Notice NOT-MH-18-045 from the NIH Guide for Grants and Contracts

Notice NOT-MH-18-044 from the NIH Guide for Grants and Contracts

Notice NOT-MH-18-043 from the NIH Guide for Grants and Contracts

Notice NOT-HD-18-013 from the NIH Guide for Grants and Contracts

Notice NOT-NS-18-090 from the NIH Guide for Grants and Contracts

Notice NOT-NS-18-091 from the NIH Guide for Grants and Contracts

Notice NOT-AT-18-015 from the NIH Guide for Grants and Contracts

Notice NOT-CA-18-103 from the NIH Guide for Grants and Contracts

Notice NOT-CA-18-104 from the NIH Guide for Grants and Contracts

Notice NOT-CA-18-101 from the NIH Guide for Grants and Contracts

Notice NOT-AG-18-026 from the NIH Guide for Grants and Contracts

Notice NOT-AG-18-027 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-ES-18-010 from the NIH Guide for Grants and Contracts. The NIEHS and partnering Institutes and Centers are establishing an infrastructure, the Human Health Exposure Analysis Resource (HHEAR) as a continuation of the Children's Health Exposure Analysis Resource (CHEAR). The goal of this consortium is to provide the research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research and to make that data publicly available as a means to improve our knowledge of the comprehensive effects of environmental exposures on human health throughout the life course. This FOA solicits the HHEAR Coordinating Center (U24) that will serve as the administrative hub and external access point for HHEAR, managing and tracking the flow of projects, materials, and analyses between HHEAR units and participating investigators. In addition, the coordinating center will support administrative functions such as convening HHEAR Steering and Executive Committee meetings, and organizing education, outreach, and publicity activities.

Funding Opportunity RFA-ES-18-012 from the NIH Guide for Grants and Contracts. The NIEHS and partnering Institutes and Centers are establishing an infrastructure, the Human Health Exposure Analysis Resource (HHEAR) as a continuation of the Children's Health Exposure Analysis Resource (CHEAR). The goal of this consortium is to provide the research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research and to make that data publicly available as a means to improve our knowledge of the comprehensive effects of environmental exposures on human health throughout the life course. This FOA solicits Laboratories (Lab Hubs) that can provide comprehensive measurement of the exposome using untargeted approaches (such as metabolomics using libraries enriched for environmental exposure biomarkers) for biological samples derived from extant or ongoing human health studies in the NIH extramural research community. Each Hub will incorporate an administrative core and a developmental core to improve the ability of untargeted platform to detect a wide range of environmental exposures and endogenous changes in response to environmental influences in a variety of biological matrices.

Funding Opportunity RFA-ES-18-011 from the NIH Guide for Grants and Contracts. The NIEHS and partnering Institutes and Centers are establishing an infrastructure, the Human Health Exposure Analysis Resource (HHEAR) as a continuation of the Children's Health Exposure Analysis Resource (CHEAR). The goal of this consortium is to provide the research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research and to make that data publicly available as a means to improve our knowledge of the comprehensive effects of environmental exposures on human health throughout the life course. This FOA solicits Laboratories (Lab Hubs) providing a comprehensive suite of targeted analytical services for biological samples derived from extant or ongoing human health studies in the NIH extramural research community. Each Hub will incorporate an administrative core and a developmental core to expand the number of commonly measured analytes and biological matrices.