NIH Funding Opportunities (Notices, PA, RFA)

Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 2 hours 40 min ago
Notice of Intent to Publish a Funding Opportunity Announcement for Intellectual and Developmental Disabilities Research Centers 2025 (P50 Clinical Trial Optional)
Notice NOT-HD-24-023 from the NIH Guide for Grants and Contracts
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Notice of Change to Increase the Application Budget Limit in PAR-23-145 "Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)"
Notice NOT-GM-24-042 from the NIH Guide for Grants and Contracts
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Translational Resource Centers to Build Bridges Between Substance Use Epidemiology/Etiology and Prevention Intervention Research (U24 Clinical Trials Not Allowed)
Funding Opportunity RFA-DA-25-040 from the NIH Guide for Grants and Contracts. The purpose of this concept is to facilitate the formation and maintenance of multidisciplinary research teams ready to employ epidemiological and/or etiological datasets and analyses to answer substance use prevention research questions and apply findings to intervention development or implementation. Projects supported through this concept will combine hands-on meeting formats, including both sandpit and hackathon approaches, with activities to sustain new research teams and networks, creating a foundational structure for research programs that have impact across disciplines.
Categories: Job Watch, Literature Watch
Clinical Trial Readiness to Understand and Develop Solutions to Social, Ethical, Behavioral Implications and Barriers to Health Equity in ADRD (R01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-25-013 from the NIH Guide for Grants and Contracts. Applications to this NOFO will propose research to establish clinical trial readiness for community-driven interventions to understand and develop solutions addressing barriers to equity in ADRD outcomes among populations defined by the NIH to experience health disparities and communities that intersect with them. Applications should consider the social, ethical, and behavioral implications (SEBI) related to assessing risk for, identification of, or treatment of ADRD among underserved and marginalized populations and how these factors may relate to existing or potential barriers to achieving equity and impact future clinical trials.
Categories: Job Watch, Literature Watch
Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional)
Funding Opportunity PAR-24-231 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support research to develop and test community-level interventions to improve minority health and reduce health disparities.
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Availability of the Final Draft 2025-2029 National Institute of Environmental Health Sciences (NIEHS) Strategic Plan and Public Comment Period
Notice NOT-ES-24-014 from the NIH Guide for Grants and Contracts
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Notice of NCCIH Participation in RFA-AA-24-006 "Model Continuums of Care Initiative (MCCI) to Advance Health Equity and End Health Disparities Among Women and Girls in Racial/Ethnic Minority and Other Underserved Communities (U34 Clinical Trials Required"
Notice NOT-AT-24-043 from the NIH Guide for Grants and Contracts
Categories: Job Watch, Literature Watch
Preapplication Webinar: Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional)
Notice NOT-CA-24-063 from the NIH Guide for Grants and Contracts
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Notice of Changes to NOT-AG-24-011, "Request for Information (RFI) for the NIA Data Linkage Program (LINKAGE): Linking Research Data with Data from the Centers for Medicare and Medicaid Services (CMS) and other Federal Sources"
Notice NOT-AG-24-024 from the NIH Guide for Grants and Contracts
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Notice of Change to Letters of Support Instructions for PAR-23-221 "Advancing Research Careers (ARC) Institutionally-Focused Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed)"
Notice NOT-GM-24-041 from the NIH Guide for Grants and Contracts
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Notice of Extension of the Expiration Date for PAR-21-226 "Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)"
Notice NOT-OD-24-131 from the NIH Guide for Grants and Contracts
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Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional)
Funding Opportunity RFA-CA-24-027 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the NCI intends to support multi-level intervention studies that address individual and system level barriers to transition from pediatric to adult care for survivors of childhood and adolescent cancers. The goal of this opportunity is to support the development and testing of interventions and strategies that promote high-quality transitional care and continued engagement of survivors of childhood and adolescent cancers to ensure these survivors receive appropriate surveillance and care into adulthood. Overall, it is anticipated that this research will provide critical evidence for establishing best practices and standards of care that can be widely disseminated and adopted.
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CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-ES-24-005 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support research seeking to understand mechanisms of chemical toxicity and to identify potential molecular/genetic targets that reduce acute effects of chemical threat agents that affect the eyes and lungs. These discoveries can lead to exploration of therapeutic countermeasures through early stage development efforts supported by the Countermeasures Against Chemical Threats (CounterACT) NIH-wide program, a component within the Chemical Countermeasures Research Program (CCRP).
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Centers for Collaborative Research in Fragile X and FMR1-Associated Conditions (P50 Clinical Trial Optional)
Funding Opportunity RFA-HD-25-002 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites new applications for Centers for Collaborative Research in Fragile X andFMR1-Associated Conditions (hereafter termed "Fragile X Centers"). Despite many remarkable advances in fundamental knowledge about FMR1-associated conditions, gaps in knowledge remain about the processes that drive the variability in clinical features (phenotypic heterogeneity) among affected individuals. In this round of competition, therefore, all centers will be required to identify an overarching theme directed at broadening our understanding of factors underlying the phenotypic heterogeneity and/or variability in response to interventions seen in one or more FMR1 associated conditions. Successful Fragile X Centers will be composed of multidisciplinary teams of basic, translational, clinical, and/or data science investigators applying precision medicine approaches (seeking to understand which mechanisms and interventions are most applicable to specific individuals or groups) to address the center's proposed overarching theme. This NOFO includes specific requirements about inclusion of research on human subjects or human phenotypic data; diversity of participants or materials being studied; the types of allowable clinical trials; and involvement of early-stage investigators. Applications that do not adhere to these requirements will be considered nonresponsive to this NOFO and will be withdrawn. In addition, this NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.Applicants are strongly encouraged to read the NOFO instructions carefully and view the availablePEDP guidance material.
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Notice of Early Termination of NIDCR Mentored Career Development Award to Promote Diversity, PAR-22-051 (K01 Clinical Trial Required) and PAR-22-052 (K01 Independent Basic Experimental Studies with Humans Required)
Notice NOT-DE-24-024 from the NIH Guide for Grants and Contracts
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Notice of NIDCR Withdrawal of Participation from Mentored Patient-Oriented Research Career Development Award, PA-24-184 (Parent K23-Independent Clinical Trial Required) and PA-24-186 (Parent K23 Independent Basic Experimental Studies with Humans Required)
Notice NOT-DE-24-023 from the NIH Guide for Grants and Contracts
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HEAL Initiative: JCOIN Phase II Innovation Hubs (R01 Clinical Trial Optional)
Funding Opportunity RFA-DA-25-062 from the NIH Guide for Grants and Contracts. Individuals in the US justice system are disproportionately likely to have SUD/OUD, are at high risk for opioid withdrawal upon incarceration, and are at elevated risk for overdose post-release if they have not received MOUD while detained. Most US jails do not offer MOUD to everyone who could benefit from them. JCOIN focuses on the translation of research-to-practice to address the overdose crisis in the context of the criminal justice system specifically, increasing delivery of and access to MOUD. A portfolio of research projects conducts hybrid effectiveness-implementation trials to address key barriers to delivery of evidence-based OUD treatments to justice-involved populations. This is the only HEAL initiative with a primary focus on justice-involved populations and criminal-legal systems.
Categories: Job Watch, Literature Watch
HEAL Initiative: JCOIN Phase II Economic Research Resource Center (U24 Clinical Trial Optional)
Funding Opportunity RFA-DA-25-061 from the NIH Guide for Grants and Contracts. Individuals in the US justice system are disproportionately likely to have SUD/OUD, are at high risk for opioid withdrawal upon incarceration, and are at elevated risk for overdose post-release if they have not received MOUD while detained. Most US jails do not offer MOUD to everyone who could benefit from them. JCOIN focuses on the translation of research-to-practice to address the overdose crisis in the context of the criminal justice system specifically, increasing delivery of and access to MOUD. A portfolio of research projects conducts hybrid effectiveness-implementation trials to address key barriers to delivery of evidence-based OUD treatments to justice-involved populations. This is the only HEAL initiative with a primary focus on justice-involved populations and criminal-legal systems.
Categories: Job Watch, Literature Watch
HEAL Initiative: JCOIN Phase II Community Engaged Research Resource Center (U24 Clinical Trial Optional)
Funding Opportunity RFA-DA-25-026 from the NIH Guide for Grants and Contracts. Individuals in the US justice system are disproportionately likely to have SUD/OUD, are at high risk for opioid withdrawal upon incarceration, and are at elevated risk for overdose post-release if they have not received MOUD while detained. Most US jails do not offer MOUD to everyone who could benefit from them. JCOIN focuses on the translation of research-to-practice to address the overdose crisis in the context of the criminal justice system specifically, increasing delivery of and access to MOUD. A portfolio of research projects conducts hybrid effectiveness-implementation trials to address key barriers to delivery of evidence-based OUD treatments to justice-involved populations. This is the only HEAL initiative with a primary focus on justice-involved populations and criminal-legal systems.
Categories: Job Watch, Literature Watch
HEAL Initiative: JCOIN Phase II Clinical Research Hubs (UM1 Clinical Trial Required)
Funding Opportunity RFA-DA-25-025 from the NIH Guide for Grants and Contracts. Individuals in the US justice system are disproportionately likely to have SUD/OUD, are at high risk for opioid withdrawal upon incarceration, and are at elevated risk for overdose post-release if they have not received MOUD while detained. Most US jails do not offer MOUD to everyone who could benefit from them. JCOIN focuses on the translation of research-to-practice to address the overdose crisis in the context of the criminal justice system specifically, increasing delivery of and access to MOUD. A portfolio of research projects conducts hybrid effectiveness-implementation trials to address key barriers to delivery of evidence-based OUD treatments to justice-involved populations. This is the only HEAL initiative with a primary focus on justice-involved populations and criminal-legal systems.
Categories: Job Watch, Literature Watch