NIH Funding Opportunities (Notices, PA, RFA)

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 54 min 1 sec ago

Notice of Participation of National Institute on Deafness and Other Communication Disorders in RFA-DA-24-040 and RFA-DA-24-041

Thu, 2024-06-06 03:43
Notice NOT-DC-24-032 from the NIH Guide for Grants and Contracts

New eRA Human Subjects System Capabilities for Awarded NIH R and D Contract Vendors to Directly Enter Inclusion Data

Thu, 2024-06-06 03:01
Notice NOT-OD-24-128 from the NIH Guide for Grants and Contracts

Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings (R01 - Clinical Trial Not Allowed)

Wed, 2024-06-05 13:30
Funding Opportunity PAR-24-234 from the NIH Guide for Grants and Contracts. Advances in structural biology have enabled the characterization of large protein assemblies that are linked to AD/ADRD pathology. However, most structural biology approaches require purified samples from cells and tissues or use recombinant bacterial proteins. The derived structures using ex-vivo material may not report the diversity of physiologically relevant species because reconstruction relies on class averaging that is biased towards dominant conformations that survive methodological processing. Recent developments in structural biology offer the possibility of in situ characterization of specific macromolecular assemblies. Structural information of protein assemblies and aggregates in their native cellular and tissue environments could facilitate rational structure-based ligand development. Currently, PET ligands that specifically identify and monitor the accumulation of aggregated and misfolded proteins in AD/ADRD patients are lacking.

T32 Training Program for Institutions That Promote Diversity (T32 Clinical Trial Not Allowed)

Wed, 2024-06-05 13:29
Funding Opportunity PAR-24-199 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to enhance the participation of individuals from nationally underrepresented backgrounds to enhance the participation of individuals from nationally underrepresented backgrounds in cardiovascular, pulmonary, hematologic and sleep disorders research across the career development continuum by providing support to institutions that promote diversity. The NHLBI's T32 Training Program for Institutions That Promote Diversity is a Ruth L. Kirschstein National Research Service Award Program intended to support training of predoctoral and health professional students and individuals in postdoctoral training institutions with an institutional mission focused on serving health disparity populations not well represented in scientific research, or institutions that have been identified by federal legislation as having an institutional mission focused on these populations, with the potential to develop meritorious training programs in cardiovascular, pulmonary, and hematologic diseases, and sleep disorders. These institutions are uniquely positioned to engage minority and other health disparity populations in research, translation, and implementation of research advances that impact health outcomes, as well as provide health care for these populations. This NOFO does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Single Source for the Continuation of the Human Pancreas Analysis Program (HPAP) for Type 1 Diabetes (HPAP-T1D) (U01 Clinical Trial Not Allowed)

Wed, 2024-06-05 04:18
Funding Opportunity RFA-DK-25-012 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) is a non-competitive funding opportunity intended to fund a single award. The NIDDK is announcing its intent to issue a single source cooperative agreement to the University of Pennsylvania to continue the mission of the existing Human Pancreas Analysis Program for Type 1 Diabetes (HPAP-T1D). This NOFO will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; immunology and autoimmunity; collection, processing and multimodal analysis of human pancreatic tissues and immune compartments; and biological database building, curation and management, that will be tasked to: 1) identify, collect and intensively characterize primary pancreatic tissues and immune cells from patients with type 1 diabetes (T1D) or at risk of developing the disease, as well as age-matched controls; and 2) analyze, organize and share the data resulting from the study of these tissues through the existing PANC DB open-access resource database. HPAP-T1D is a component of the Human Islet Research Network or HIRN. HIRN was created in 2014 to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional human beta cell mass.

Notice of Special Interest (NOSI): Conferences and Scientific Meetings in Cancer Biology

Tue, 2024-06-04 12:22
Notice NOT-CA-24-059 from the NIH Guide for Grants and Contracts

Guidance Regarding Reduction of Effort for NIMHD Individual Mentored K Awards

Tue, 2024-06-04 04:43
Notice NOT-MD-24-017 from the NIH Guide for Grants and Contracts

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