NIH Funding Opportunities (Notices, PA, RFA)

Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 9 min 16 sec ago
Notice of Expiration of RFA-RM-15-018: "Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Comprehensive Functional Mapping of Neuroanatomy and Neurobiology of Organs (OT2)"
Notice NOT-RM-18-015 from the NIH Guide for Grants and Contracts
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Mechanistic investigations of psychosocial stress effects on opioid use patterns (R01- Clinical Trial Optional)
Funding Opportunity PAS-18-624 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites innovative research to characterize the consequences of psychosocial stress on affective/cognitive functioning and/or pain processing as it relates to opioid use disorder (OUD). This FOA encourages research that elucidates mechanisms of action and determinants of vulnerability and/or resilience by which psychosocial stress influence OUD trajectories. Research using basic or clinical approaches is appropriate.
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Mechanistic investigations of psychosocial stress effects on opioid use patterns (R21- Clinical Trial Optional)
Funding Opportunity PAS-18-625 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites innovative research to characterize the consequences of psychosocial stress on affective/cognitive functioning and/or pain processing as it relates to opioid use disorder (OUD). This FOA encourages research that elucidates mechanisms of action and determinants of vulnerability and/or resilience by which psychosocial stress influence OUD trajectories. Research using basic or clinical approaches is appropriate.
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NINDS Exploratory Clinical Trials for Small Business (R42) - Clinical Trial Required
Funding Opportunity PAR-18-617 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to provide a vehicle for Small Business Concerns (SBCs) submitting Small Business Technology Transfer (STTR) grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The projects must focus on products related to the mission and goals of the NINDS and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Only STTR Phase II and Fast-Track applications are supported under this program. STTR Phase I applications are only accepted as part of a Fast-track application.
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Research to Support the Reduction and Elimination of Mental Health Disparities (Admin Supp Clinical Trial Optional)
Funding Opportunity PA-18-621 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to support Administrative Supplements to active NIMH grants to foster research across the NIMH Strategic Objectives that target the reduction and elimination of mental health disparities by race and ethnicity, geography, and socioeconomic status in the United States. This initiative aims to generate research within the scientific scope of the parent grant that identifies mechanisms underlying disparities or differences in mental health status and/or enhances optimal delivery of mental health interventions among diverse groups.
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Disease Mechanisms of Prenatal and Pediatric Hydrocephalus (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-622 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support hypothesis-driven research of prenatal and pediatric hydrocephalus. This FOA intends to solicit hydrocephalus research projects that examine the developmental etiology (intrinsic factors including genetics) and acquired etiology (extrinsic factors including hemorrhage and infection) of prenatal and/or pediatric hydrocephalus. Studies should focus on understanding the molecular, cellular and developmental mechanisms involved in the pathogenesis of prenatal and/or pediatric hydrocephalus.
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Tools to Enhance the Study of Prenatal and Pediatric Hydrocephalus (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-18-623 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage research grant applications that propose to develop or substantially modify existing cutting-edge tools that will advance prenatal and/or pediatric hydrocephalus research. The primary objective of this FOA is to remove barriers to hydrocephalus research that are due to scarcity of tools to investigate both the disease mechanisms and alternative therapies (non-shunt) in a rigorous manner. Applications should aim to transform the field of prenatal and/or pediatric hydrocephalus research by generating tools including animal and cell models, novel methods and innovative technologies that will be widely used throughout the neuroscience community to understand disease mechanisms and/or developing therapeutics.
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Traceback Testing: Increasing Identification and Genetic Counseling of Mutation Carriers through Family-based Outreach (U01 Clinical Trial Optional)
Funding Opportunity PAR-18-616 from the NIH Guide for Grants and Contracts. The purpose of the Funding Opportunity Announcement (FOA) is to support research projects using a Traceback approach to genetic testing to identify unaffected individuals at increased risk for cancer in different clinical contexts and communities, including racially/ethnically diverse populations.
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Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01 - Clinical Trial Optional)
Funding Opportunity PA-18-619 from the NIH Guide for Grants and Contracts. The purpose of this FOA is encourage applications that seek to examine processes of recovery and relapse in the treatment of Alcohol Use Disorders. Applications high in innovation and significance are highly encouraged that address the following potential topics: 1) defining recovery; 2) Examining new and innovative methods to examine precipitants of relapse; 3) Understanding mechanisms of mutual help and recovery; 4) Evaluating recovery systems of care; and 5) Examining processes of extended treatment for AUD.
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Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R01 Clinical Trial Optional)
Funding Opportunity PAR-18-612 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement is to support studies on electronic nicotine delivery systems (ENDS) that examine population-based, clinical and applied prevention of disease, including etiology of use, epidemiology of use, potential risks, benefits and impacts on other tobacco use behavior among different populations.
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Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R21 Clinical Trial Optional)
Funding Opportunity PAR-18-611 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement is to support studies on electronic nicotine delivery systems (ENDS) that examine population-based, clinical and applied prevention of disease, including etiology of use, epidemiology of use, potential risks, benefits and impacts on other tobacco use behavior among different populations.
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Pilot and Feasibility Studies of HIV and Animal Models for HIV Infection within the Mission of NIDDK (R21 Clinical Trial Optional)
Funding Opportunity PA-18-615 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for innovative basic and translational research projects examining HIV infection, persistence, and comorbidities as they relate to the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and consistent with the scientific priorities outlined by the NIH Office of AIDS Research (OAR) in NOT-OD-15-137.
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Notice of Correction to Key Dates to PAR-18-361, "Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional)"
Notice NOT-CA-18-052 from the NIH Guide for Grants and Contracts
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Notice to Clarify Application Due Dates for PAR-18-028, "Phase III Clinical Trials for the Spectrum of Alzheimer's Disease and Age-related Cognitive Decline"
Notice NOT-AG-18-004 from the NIH Guide for Grants and Contracts
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Notice Announcing Frequently Asked Questions (FAQs) for PAR-18-577, New Epidemiology Cohort Studies in Heart, Lung, Blood, and Sleep Diseases and Disorders (U01 Clinical Trials Not Allowed)
Notice NOT-HL-18-590 from the NIH Guide for Grants and Contracts
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Request for Proposals (RFP) Notice: Synthesis and Distribution of Drugs of Abuse and Related Compounds
Notice NOT-DA-18-060 from the NIH Guide for Grants and Contracts
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Notice of Pre-Application Webinar for PAR-18-583 "Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)"
Notice NOT-RM-18-013 from the NIH Guide for Grants and Contracts
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Training Modules to Enhance the Rigor and Reproducibility of Biomedical Research (R25 Clinical Trial Not Allowed)
Funding Opportunity RFA-GM-18-002 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs and foster a better understanding of biomedical, behavioral and clinical research and its implications.
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NINDS Exploratory Clinical Trials for Small Business (R44) - Clinical Trial Required
Funding Opportunity PAR-18-618 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to provide a vehicle for Small Business Concerns (SBCs) submitting Small Business Innovation Research (SBIR) grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The projects must focus on products related to the mission and goals of the NINDS and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Only SBIR Phase II and Fast-Track applications are supported under this program. SBIR Phase I applications are only accepted as part of a Fast-track application.
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National Centers for Translational Research in Reproduction and Infertility [NCTRI] (P50 - Clinical Trial Optional)
Funding Opportunity RFA-HD-19-017 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to announce the re-competition of the National Centers for Translational Research in Reproduction and Infertility (NCTRI). The NCTRI will be administered through the Specialized Research Center (P50) award mechanism. These centers will form a national network that facilitates and accelerates bidirectional knowledge transfer between the laboratory and clinic with the ultimate goal of improving human reproductive and gynecological health through research excellence and innovation.
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