Notice NOT-HS-17-014 from the NIH Guide for Grants and Contracts

Notice NOT-NS-17-020 from the NIH Guide for Grants and Contracts

Notice NOT-AI-17-025 from the NIH Guide for Grants and Contracts

Notice NOT-HS-17-013 from the NIH Guide for Grants and Contracts

Notice NOT-AI-17-024 from the NIH Guide for Grants and Contracts

Notice NOT-FD-17-009 from the NIH Guide for Grants and Contracts

Notice NOT-HL-17-495 from the NIH Guide for Grants and Contracts

Notice NOT-CA-17-053 from the NIH Guide for Grants and Contracts

Notice NOT-AA-17-003 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DK-17-507 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites an application from the Program Director/Principal Investigator of the Data Coordinating Center (DCC) that is currently supporting the research being performed by the complex and effective Type 1 Diabetes TrialNet network. This FOA will support the design and conduct of new-onset trials (as selected by the TrialNet Steering Committee) aimed at preservation of insulin-producing cells in individuals with new-onset diabetes.

Notice NOT-DA-17-029 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-RM-17-007 from the NIH Guide for Grants and Contracts. The NIH Director's Transformative Research Award complements NIHs traditional, investigator-initiated grant programs by supporting individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Little or no preliminary data are expected. Projects must clearly demonstrate the potential to produce a major impact in a broad area of biomedical or behavioral research. The NIH Directors Transformative Research Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

Funding Opportunity PA-17-261 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites R18 grant applications for developing new clinical decision support (CDS) to facilitate the dissemination and implementation of evidence-based research findings. The purposes of this FOA are to develop new, reliable, valid, and usable CDS from evidence-based research findings and then demonstrate its effectiveness to improve care in clinical practice.

Funding Opportunity PA-17-260 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites R18 grant applications for research projects to scale and spread existing clinical decision support (CDS) to facilitate the dissemination and implementation of evidence-based research findings into clinical practice. The purposes of this FOA are to extend the implementation ("scale") and evaluation of well-established and effective CDS beyond the initial clinical setting or institution in which the CDS was originally developed and implemented, thereby extending the impact on clinical practice.

Funding Opportunity RFA-RM-17-005 from the NIH Guide for Grants and Contracts. The NIH Directors Pioneer Award complements NIH's traditional, investigator-initiated grant programs by supporting individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges that have the potential to produce an unusually high impact on enhancing health, lengthening life, and reducing illness and disability. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigators research program or elsewhere. The NIH Directors Pioneer Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

Notice NOT-AT-17-008 from the NIH Guide for Grants and Contracts

Notice NOT-AT-17-007 from the NIH Guide for Grants and Contracts

Notice NOT-AI-17-011 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AR-18-004 from the NIH Guide for Grants and Contracts. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) requests applications for the NIAMS Resource-based Centers Program (P30) for rheumatic diseases research areas within its mission. The Resource-based Centers will provide critical research infrastructure, shared facilities, services, and/or resources to groups of investigators conducting research on rheumatic diseases, enabling them to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively, with the broad overall goal of accelerating, enriching, and enhancing the effectiveness of ongoing basic, translational, and clinical research and promoting new research within the NIAMS mission.

Funding Opportunity RFA-MH-18-251 from the NIH Guide for Grants and Contracts. This Limited Competition Funding Opportunity Announcement (FOA) invites one application to continue the activities of the Data Coordinating Center (DCC) of the National NeuroAIDS Tissue Consortium as previously funded under RFA-MH-13-071. The DCC will function as part of the NNTC, a national resource that provides clinical data and biological specimens to NeuroAIDS investigators interested in conducting research toward a cure of Human Immunodeficiency Virus (HIV-1) infection from the central nervous system (CNS), and research on the neuropathogenesis of HIV-1 induced CNS and peripheral nervous system (PNS) dysfunction in the context of anti-retroviral therapy (ART). The DCC works cooperatively with the NNTC-affiliated clinical sites to provide the following: 1) management and database capabilities to ensure effective clinical and brain banking operations, and to serve as the data repository for the NNTC; 2) scientific expertise in biostatistics and HIV-1 epidemiology to enable broad analyses of the NNTC clinical database, and to aid in statistical analysis of recruitment and retention goals for the clinical sites affiliated with the NNTC; and 3) expanding the capability to include coordinating the distribution of data and specimens stored at other national and international clinical sites to ensure that NeuroAIDS investigators have access to CNS and PNS resources that are difficult to obtain from HIV-1 infected individuals across the lifespan. The clinical sites affiliated with the NNTC will have all patient contact which will include all clinical assessments ante mortem. The clinical sites will also be responsible for the collection and housing of post mortem clinical specimens. The DCC will serve as a NeuroAIDS data repository which will include the clinical assessment data and data obtained post mortem including brain pathology reports, laboratory tests conducted on the collected specimens/fluids, a comprehensive inventory of those specimens housed at each clinical site, and research data, such as bioinformatics datasets. A limited competition application for the NNTC DCC is being sought under a separate but related companion FOA (RFA-MH-18-250)