Funding Opportunity RFA-TR-23-018 from the NIH Guide for Grants and Contracts. This NOFO provides support using the STTR cooperative agreement mechanisms for the development of MATChS. Applications considered responsive to this would include those proposing research and development of tools and turnkey technologies for higher throughput automated measures with on-line sensing, rapid acquisition and analysis of data to reduce manual handling. Funded projects will result in an increased availability of miniaturized automated tissue chip platforms for use in drug development and across multiple applications as a major research tool in biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) will be expected to develop milestones and benchmarks, and work with NIH staff towards progress in the aims of the project to develop an automated system and demonstrable pathways to commercialization.

Funding Opportunity RFA-TR-23-017 from the NIH Guide for Grants and Contracts. This NOFO provides support using the SBIR cooperative agreement mechanisms for the development of MATChS. Applications considered responsive to this would include those proposing research and development of tools and turnkey technologies for higher throughput automated measures with on-line sensing, rapid acquisition and analysis of data to reduce manual handling. Funded projects will result in an increased availability of miniaturized automated tissue chip platforms for use in drug development and across multiple applications as a major research tool in biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) will be expected to develop milestones and benchmarks, and work with NIH staff towards progress in the aims of the project to develop an automated system and demonstrable pathways to commercialization.

Funding Opportunity PAR-24-065 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The projects may be supported by core units, if justified, to facilitate economy of effort, space, and equipment. The NHLBI provides support for Program Project Grants (PPGs) in the belief that collaborative research efforts can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects that have no interaction or thematic integration. NHLBI is particularly interested in encouraging new scientific directions in PPGs. Use of the P01 activity code is viewed as an opportunity to attract scientists who have not traditionally been supported by the NHLBI. Further, the PPG environment presents an opportunity for emerging scientific leaders to gain insight into how to lead a successful scientific Program, and applicants will have the opportunity to include a project led by an Early Stage Investigator (ESI). All projects in the Program must be interrelated and have objectives that address a central theme within the scientific mandate of the NHLBI.

Notice NOT-NS-24-034 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-014 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-25-030 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages exploratory and developmental research to better understand adolescent illicit fentanyl use and overdose patterns among youth at high risk for overdose. Research studies should identify targets for overdose prevention and substance use disorder (SUD) treatment and recovery. Research studies may use a variety of approaches (e.g., leveraging existing data sources, survey research, social network analysis, new methods development, feasibility research). Outcomes of interest include but are not limited to prevalence of overdose and reduction in substance use, particularly fentanyl use or use of drugs that are commonly laced with fentanyl; unintentional use/overdose, use/overdose by risk group, stigma, family and environmental risk and protective factors, treatment engagement, youth perceptions of substance use, and optimistic bias.

Notice NOT-CA-24-013 from the NIH Guide for Grants and Contracts

Notice NOT-ES-24-001 from the NIH Guide for Grants and Contracts

Notice NOT-AI-24-005 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-25-031 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages pilot work and preliminary research to support preparation for large-scale, rigorous trials that will guide the expansion of effective, non-stigmatizing overdose prevention, SUD treatment and recovery services for adolescents. These studies could include examining changes in risk behaviors associated with overdose (e.g., using alone, carrying/using Naloxone). Outcomes of interest include but are not limited to harm reduction, recovery, treatment retention and effectiveness, quality of care, patient-centered outcomes, and implementation factors. The goal of this NOFO is to develop interventions that address effective, non-stigmatizing overdose prevention, SUD treatment and recovery services for youth that are effective, practical, cost-effective, scalable, and sustainable.

Notice NOT-DA-23-045 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-009 from the NIH Guide for Grants and Contracts

Notice NOT-HS-24-004 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-026 from the NIH Guide for Grants and Contracts

Notice NOT-MD-23-019 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-061 from the NIH Guide for Grants and Contracts. This program will support the development and implementation of short courses to prepare nurse scientists, and scientists in aligned fields, to conduct firearm injury prevention research in support of the NINR Strategic Plan (https://www.ninr.nih.gov/aboutninr/ninr-mission-and-strategic-plan). Applications are encouraged that build on the existing knowledge, approaches, methods, and techniques related to injury prevention to advance research specifically in the area of firearm injury. Applications should include content related to inequities in firearm injuries (e.g., race, ethnicity, socioeconomic position, gender, geography, and their intersections) and research at the individual, community, institutional, and structural levels.

Notice NOT-NS-24-031 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-029 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-011 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-071 from the NIH Guide for Grants and Contracts