Funding Opportunity PAR-23-287 from the NIH Guide for Grants and Contracts. The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is designed specifically for candidates proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Those not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO (PAR-23-286).

Funding Opportunity PAR-23-286 from the NIH Guide for Grants and Contracts. The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This Notice of Funding Opportunity (NOFO) is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Under this NOFO candidates are permitted to propose a research experience in a clinical trial led by a mentor or co-mentor. Those proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFOs (PAR-23-287 or PAR-23-288).

Notice NOT-DK-24-002 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-017 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-064 from the NIH Guide for Grants and Contracts

Notice NOT-OH-24-002 from the NIH Guide for Grants and Contracts

Notice NOT-AI-24-004 from the NIH Guide for Grants and Contracts

Notice NOT-HG-24-008 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-062 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support translational research across epidemiology, services, and prevention research to relieve the burden of substance use on public health. This NOFO solicits applications that start with a planning phase, which if successful will be able to translate rapidly from hypotheses to intervention, or from pilot to implementation, with potential for transformative findings through innovative translational research.

Funding Opportunity RFA-OD-24-006 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to seek applications for a Coordinating Center (CC) for the Multi-Sectoral Preventive Interventions (MSPI) Research Network. Members of the Multi-Sectoral Preventive Interventions (MSPI) Research Network, including the CC and separately funded research projects, will work collaboratively with the NIH to test prospective multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities. The MSPI Research Network will include the CC funded under this Cooperative Agreement and up to 10 Research Projects funded under the companion UG3/UH3 Phased Cooperative Agreement NOFO, Multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities. The CC will provide overarching support and guidance to the network in three domains: (1) administration, coordination, and communication; (2) methodology, data, and analytic support and consultation; and (3) community and other collaborator engagement and dissemination support. It is important that applicants for the CC also read the companion NOFO to understand the full mission and structure of the research network.

Funding Opportunity RFA-DA-24-036 from the NIH Guide for Grants and Contracts. The goal of the initiative is to test prevention and harm reduction strategies, extending the continuum of care within the U.S. rural communities impacted by the opioid/psychostimulant misuse epidemic to reduce risks for individuals with unmet prevention and harm reduction needs.

Notice NOT-AT-24-024 from the NIH Guide for Grants and Contracts

Notice NOT-AA-24-002 from the NIH Guide for Grants and Contracts

Notice NOT-TR-24-001 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-288 from the NIH Guide for Grants and Contracts. The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Those not planning an independent clinical trial or basic experimental study with humans, or proposing to gain research experience in a clinical trial or basic experimental study with humans led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO (PAR-23-286).

Notice NOT-AT-24-025 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-25-029 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) seeks applications for a single Coordinating Center to support research on the identification and dissemination of signals of emerging drug use patterns in communities across the United States. The Coordinating Center will provide operational, administrative, and logistical support by executing the following: (1) Establish a Scientific Advisory Group to provide guidance and direction. (2) Engage an Early Warning Network composed of two components: local health experts on drug use from selected communities (Sentinel Sites) and a broader network of community-based health researchers, to support the bi-directional sharing of information and insights into drug use patterns in their communities and to support the ongoing monitoring, interpretation, and dissemination of data. (3) Identify, compile, analyze, and triangulate research data and resources from multiple sources to assess and contextualize emerging drug threats. (4) Disseminate contextualized research findings, data, and resources to key audiences who can use the data to inform their response.

Funding Opportunity RFA-DA-25-027 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications from clinical investigators to participate in the National Drug Abuse Treatment Clinical Trials Network (CTN) and contribute to the network's capacity to respond to urgent public health needs. NIDA intends to continue to develop and test interventions for addressing the wide spectrum of substance use problems via collaborative partnerships among NIDA, clinical research investigators, community representatives, healthcare providers, and healthcare institutions.

Notice NOT-NR-24-002 from the NIH Guide for Grants and Contracts

Notice NOT-CA-24-001 from the NIH Guide for Grants and Contracts