Notice NOT-EB-23-007 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-015 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-114 from the NIH Guide for Grants and Contracts

Funding Opportunity PA-23-196 from the NIH Guide for Grants and Contracts. This announcement represents the continuation of an AHRQ program that provides support to individuals who are conducting research undertaken as part of an accredited academic program to qualify for a research doctorate degree.

Funding Opportunity RFA-DK-23-012 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support a Human Liver Tissue and Hepatocytes Research Resource (HLTHRR) program to enable the continued availability of human liver tissue and hepatocytes to biomedical researchers. The research resource is expected to facilitate the procurement and preservation of human liver tissue and hepatocytesas well as the distribution of these materials to qualified biomedical researchers. Applications focused on animal liver and/or hepatocytes studies will not be considered responsive to this NOFO.

Notice NOT-TR-23-015 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-NS-24-011 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) supports the development of PET radioligands that identify proteinopathies or pathological processes associated with the human biology of Alzheimer's disease related dementias (ADRDs). Activities supported under this FOA include, but are not limited to the in vitro screening of existing ligands against human ADRD brain tissue, medicinal chemistry support for development of new compounds and improvement of existing ligand specificity and selectivity, initial screening of ligands in appropriate animal models, and radioligand formulation and first-in-human testing. The Center without Walls should encompass research that will move promising ligands through in vitro and in vivo optimization to first-in-human studies. Applications must include an administrative core, a medicinal chemistry core, a clinical core, a scientific governance structure, and a minimum of two research projects with milestone plans that address workflows for screening of existing and newly derived ligands against human ADRD tissue and appropriate animal models. Synergy must be evident among Center research projects and cores, such that successful completion of the aims could not be accomplished without the Center structure. This FOA is in response to the Alzheimer's Disease Related Dementias (ADRD) challenges outlined in the 2016 update to the National Plan to Address Alzheimer's Disease.

Funding Opportunity RFA-OD-23-017 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity Announcement (NOFO) is to invite R01 applications to support biomedical and behavioral research that will provide scientific data to inform the regulation of tobacco products to protect public health. Research Projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP). The awards under this NOFO will be administered by NIH using funds that have been made available through FDA CTP and the Family Smoking Prevention and Tobacco Control Act (P.L. 111-31). Research results from this NOFO are expected to generate findings and data that are directly relevant to informing the FDA's regulation of the manufacture, distribution, and marketing of tobacco products to protect public health.

Funding Opportunity RFA-RM-23-021 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to invite applications for Chemical Analysis Sites to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). This is a limited competition FOA and open only to the previously funded grantees of MoTrPAC Chemical Analysis sites through RFA-RM-15-010 and RFA-RM-15-011. Awards made through this FOA will support participation of grantees in the MoTrPAC consortium activities and the continuation of the analysis of tissues collected by the MoTrPAC consortium. Awardees will conduct omics analysis of tissues collected from human participants undergoing a physical activity intervention, generate well curated datasets, contribute that data to a public consortium database, and participate in the data analysis to generate molecular fingerprints of candidate transducers of physical activity.

Funding Opportunity RFA-RM-23-020 from the NIH Guide for Grants and Contracts. This limited competition FOA invites applications for a Bioinformatics Center to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). The overall goals of the Bioinformatics Center are to provide a database and associated tools for storage and integration of clinical physiological and metabolic data along with multiple types of chemical analysis data derived through metabolomics, proteomics, genomics, transcriptomics, or similar technologies. The Bioinformatics Center coordinates implementation of data and ontology-based metadata standards, provides tools for analysis and visualization of data, provides rapid access to accumulated data and tools through the use of cloud-based computing, and leads data analysis of the diverse datasets submitted by other MoTrPAC elements.

Funding Opportunity RFA-DA-24-019 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) seeks applications of limited scope proposing a set of planning activities that will lay the groundwork for a scientific project aiming to use animal models and longitudinal research designs to elucidate mechanisms mediating the impact of the early-life social environment on neurobehavioral development and the emergence of SUD risk-relevant behaviors. This planning grant funding opportunity will support planning and development of the research framework, design, and approach; including activities that will establish feasibility, validity, and/or other technically qualifying results that, if successful, would support a competitive application for an R01or equivalent NIH research award.

Notice NOT-AA-23-009 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-NS-24-020 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) aims to support the establishment of programs to enhance research rigor and transparency practices within academic and research institutions to promote a culture of high-quality neuroscience research. Attention to principles of rigorous study design and transparent reporting are essential to enable the neuroscientific community, as well as the biomedical community at large, to design and perform valid experiments and to assess the value of scientific findings. Awards are intended to support the implementation of innovative programs, strategies, and approaches at the departmental, inter-departmental, or equivalent intra-institutional entity level.

Funding Opportunity RFA-OD-23-051 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support dissemination and implementation (D and I) research focused on increasing access to and uptake of coronavirus disease 2019 (COVID-19) testing interventions with the goal of reducing COVID-19 disparities and promoting health equity among underserved and vulnerable populations. This NOFO will support D and I research on how evidence-based practices, interventions, and policies are effectively translated to and used in real-world settings. Projects may evaluate the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, or seek to understand the de-implementation of practices that are ineffective, low-value, or inequitable. Interventions developed through the Rapid Acceleration of Diagnostics Underserved Populations (RADx-UP) initiative are encouraged, but not required. The funding for this program is provided from the American Rescue Plan Act of 2021, Public Law 117-2.

Funding Opportunity RFA-OD-23-050 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) will support analyses of existing RADx-UP data by proposing novel questions related to SARS-CoV-2 testing and health disparities. These projects will explore important questions focused on COVID-19 testing access and uptake, factors affecting testing and related COVID-19 outcomes, and meta-analyses of specific COVID-19 response and intervention approaches within and across populations.

Notice NOT-HS-23-012 from the NIH Guide for Grants and Contracts

Notice NOT-AA-23-010 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-175 from the NIH Guide for Grants and Contracts. The NEI Center Core Grant combines three or more Resource and/or Service Cores for a group of R01 investigators to enhance their research, consolidate resources, avoid duplication of efforts, and/or contribute to cost effectiveness by providing a service with lower costs or higher quality than could be attempted for independent projects by several individual Program Directors/Principal Investigators (PD(s)/PI(s)). Shared resources and facilities that are accessible to a group of independently funded investigators lead to greater productivity for the separate projects and can provide instrumentation and facilities that are too costly to be maintained by an individual investigator. The design and purpose of each Center Core may vary in how it serves its users. This program is designed to enhance an institution's environment and capability to conduct vision research and to facilitate collaborative studies of the visual system and its disorders and promote new research within the NEI mission and Strategic Plan.

Notice NOT-AT-24-006 from the NIH Guide for Grants and Contracts

Notice NOT-AT-24-007 from the NIH Guide for Grants and Contracts