Funding Opportunity PAR-20-285 from the NIH Guide for Grants and Contracts. This FOA encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions; biomarker or outcome measure validation studies that are immediately preparatory to trials in stroke prevention, treatment, and recovery; and ancillary studies designed to add scientific aims to active studies being conducted within StrokeNet. Successful applicants will collaborate and conduct the study within the NIH StrokeNet. Following peer review, NINDS will prioritize studies among the highest scoring to be conducted in the NIH StrokeNet infrastructure. The NIH StrokeNet National Coordinating Center (NCC) will work with the successful applicant to implement the proposed study efficiently and the National Data Management Center (NDMC) will provide statistical and data management support. The NIH StrokeNet Regional Coordinating Centers (RCCs) and their affiliated clinical sites will provide recruitment/retention support as well as on-site implementation of the clinical protocol.

Notice NOT-CA-20-083 from the NIH Guide for Grants and Contracts

Notice NOT-RM-20-024 from the NIH Guide for Grants and Contracts

Notice NOT-OD-20-151 from the NIH Guide for Grants and Contracts

Notice NOT-DA-20-075 from the NIH Guide for Grants and Contracts

Notice NOT-CA-20-094 from the NIH Guide for Grants and Contracts

Notice NOT-RM-20-023 from the NIH Guide for Grants and Contracts

Notice NOT-RM-20-022 from the NIH Guide for Grants and Contracts

Notice NOT-CA-20-093 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-NS-20-031 from the NIH Guide for Grants and Contracts. The National Institute of Neurological Disorders and Stroke (NINDS) is soliciting applications for a Human Biospecimen and Data Repository for Biomarkers Research ("Biomarkers Repository") in Neurological Disorders. Collaborative teams combining expertise in neuroscience, biomarkers, biospecimen handling, and data management are encouraged. Experience in biomarker research, such as evaluation of batch effects, protocol development, and analyte quality control measures, is expected. Successful applications will include a detailed description of 1) Administrative Structure, 2) Research and Resource Plan, and 3) Data Management and Web-Based activities.

Notice NOT-OD-20-150 from the NIH Guide for Grants and Contracts

Notice NOT-OD-20-147 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-20-254 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites Research Project Grant (R01) applications that propose to study the ethical, legal and social implications (ELSI) of human genome research. Applications may propose studies using either single or mixed methods. Proposed approaches may include but are not limited to data-generating qualitative and quantitative approaches, legal, economic and normative analyses, and other types of analytical and conceptual research methodologies, such as those involving the direct engagement of stakeholders.

Funding Opportunity PAR-20-255 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites Exploratory/Developmental Research Grant (R21) applications that propose to study the ethical, legal and social implications (ELSI) of human genome research. These applications should propose single or mixed methods studies that break new ground, extend previous discoveries in new directions or develop preliminary data in preparation for larger studies. Of particular interest are studies that explore the implications of new or emerging genomic technologies or novel uses of genomic information.

Funding Opportunity RFA-AG-21-029 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications that apply a cross-disciplinary and team science approach to gain comprehensive mechanistic understanding of the impact of sex differences on the trajectories of brain aging, phenotypes, and risk of Alzheimer's Disease (AD) and AD-related dementia (ADRD), and on precision medicine for treatment and prevention of AD/ADRD, including the responsiveness to pharmacologic and non-pharmacologic interventions.

Funding Opportunity PAR-20-279 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the development of devices to treat Substance Use Disorders (SUDs). The continuing advances in technologies offer unprecedented opportunities to develop neuromodulatory or neurophysiological devices that are safe and effective SUD treatments. The objective is to move devices to their next step in the FDA approval process, with the ultimate goal of generating new, FDA approved device-based treatments for SUDs.

Notice NOT-CA-20-092 from the NIH Guide for Grants and Contracts

Notice NOT-DA-20-072 from the NIH Guide for Grants and Contracts

Notice NOT-AG-20-044 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-OH-21-003 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to extend and expand the World Trade Center Health Registry developed and managed by the New York City Department of Health and Mental Hygiene in a cooperative agreement with CDC. The new project will ensure ongoing data collection for victims of the September 11, 2001, terrorist attacks on the World Trade Center (WTC). The registry will continue to provide a central, unified database to assess short-term and long-term health effects among persons exposed to the WTC disaster.