NIH Funding Opportunities (Notices, PA, RFA)

Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 1 hour 25 min ago
Updating the Definition of Sexual and Gender Minority Populations in NIH-Supported Research
Notice NOT-OD-24-169 from the NIH Guide for Grants and Contracts
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Notice of Extension of PAR-21-239 "NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 No Independent Clinical Trials)"
Notice NOT-MH-24-360 from the NIH Guide for Grants and Contracts
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State-based Healthcare Extension Cooperatives to Accelerate Implementation of Actionable Knowledge into Practice (U19)
Funding Opportunity RFA-HS-24-004 from the NIH Guide for Grants and Contracts. This NOFO invites applications to establish and support State-based Healthcare Extension Cooperatives (referred to as Cooperatives) to conduct an initiative that is based on PCOR evidence to improve care for medically underserved people; the initiative's focus must be on behavioral healthcare. To support this initiative, the Cooperative will (1) engage key stakeholders including Medicaid agencies, managed care organizations, and other organizations that address the health needs of people who are medically underserved in identifying and addressing barriers and facilitators to implementing patient-centered healthcare delivery improvements that are based on PCOR evidence, (2) work with healthcare policy, payment, community, care delivery, and research organizations that serve people who are medically underserved to build their capacity to implement patient-centered healthcare delivery improvements based on PCOR evidence, and to support ongoing learning, (3) conduct evaluations of the Cooperative's activities and (4) provide the support structure to ensure these activities are integrated and aligned.
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Consortium for Neuroscience AD/ADRD in Low- and Middle-Income Countries (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-25-032 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) promotes collaborative research programs to support innovative and sustainable Alzheimer's disease (AD) and AD-related dementias (AD/ADRD) (including frontotemporal dementia (FTD), Lewy body dementia (LBD), vascular cognitive impairment/dementia (VCID), and mixed etiology dementias (MEDs)) neuroscience research for experienced investigators in low- and middle-income countries (LMICs). These collaborative research programs are expected to contribute to the long-term goals of building sustainable AD/ADRD neuroscience capacity and research, ultimately leading to prevention and mitigation strategies for AD/ADRD in LMICs. This NOFO will support applications submitted from LMIC institutions. LMIC scientists are expected to collaborate with scientists from the United States. Income categories for LMICs are defined by the World Bank athttp://data.worldbank.org/about/country-classifications/country-and-lending-groups.
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Small Research Grant Program for the Next Generation of Researchers in Low- and Middle-Income Countries (LMICs) for Aging and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) Research (R03 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-25-031 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) will support junior faculty investigators involved in aging and Alzheimer's Disease (AD) and AD-related dementia (ADRD) research from low- and middle-income countries (LMICs), as defined by the World Bank. This NOFO will support proposals submitted from LMIC institutions. and through this NOFO, NIA will: (1) Support junior investigators from LMICs to conduct aging, AD and/or ADRD research in their respective LMICs; and (2) Support the career development of junior faculty investigators as future leaders in aging, AD and/or ADRD research from LMICs. In support of the program's goal, this NOFO invites applications that will yield pilot data, resources and experience for subsequent aging, AD and/or ADRD research projects. In addition, candidates are encouraged to seek out a supportive research environment that will achieve the goal of fostering the career development of junior investigators.
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Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-291 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer health disparities, such as (1) mechanistic studies of biological factors associated with cancer health disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This NOFO is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.
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Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-25-044 from the NIH Guide for Grants and Contracts. Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter term outcomes such as weight loss and diabetes. The goal of this NOFO is to support proof of concept studies for feasibility and exploratory development. Feasibility must not have already been developed in the literature or with preliminary data. While unpublished data are not permitted, references and data from widely available preprints that have a Digital Object Identifier (DOI) are acceptable. Investigators who have generated unpublished preliminary data should submit a proposal to companion R01.
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Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
Funding Opportunity PAR-25-043 from the NIH Guide for Grants and Contracts. Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes.
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Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-277 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This NOFO is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.
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NIA Advanced Postdoctoral Career Transition Awards to Promote Diversity in Translational Research for AD/ADRD (K99/R00 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-271 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to promote diversity in the translational research workforce for Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD), including frontotemporal dementia, Lewy body dementia, and vascular dementia. This pathway to independence award will support early career investigators from diverse backgrounds to gain critical translational research skills that they can apply to various aspects of AD/ADRD research (from populations studies to research that can lead to new treatments and diagnostics, including all aspects of behavioral and social research). This program will support highly trained translational researchers as they transition to research independence in the field of AD/ADRD . The long-term goal of this program is to exand the pool of translational researchers who can effectively participate in and/or lead a team-science, interdisciplinary approach to studies of AD/ADRD treatment, prevention, early detection, and disease management and care. This Notice of Funding Opportunity (NOFO) is designed for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Under this NOFO candidates are permitted to propose a research experience in a clinical trial led by a mentor or co-mentor.
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Notice of Participation of the National Institute of Nursing Research (NINR) in PA-24-141, "NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)"
Notice NOT-NR-24-010 from the NIH Guide for Grants and Contracts
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Notice of Correction to the Eligible Individuals (PD/PI) Section for the NIHs Parent Mentored Patient-Oriented Research Career Development Award (Parent K23s) and the Midcareer Investigator Award in Patient-Oriented Research (Parent K24s)
Notice NOT-OD-24-168 from the NIH Guide for Grants and Contracts
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Notice of Special Interest: Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS)
Notice NOT-HG-24-040 from the NIH Guide for Grants and Contracts
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Notice of Special Interest: Small Business Solutions to Enable Regional Genomic Medicine eConsult Services
Notice NOT-HG-24-041 from the NIH Guide for Grants and Contracts
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Notice of Correction for RFA-DE-25-004 Collaborative Science to Achieve Disruptive Innovations in Dental, Oral and Craniofacial (DOC) Research (RM1 Clinical Trial Not Allowed)
Notice NOT-DE-25-036 from the NIH Guide for Grants and Contracts
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Clinical and Translational Science Award (UM1 Clinical Trial Optional)
Funding Opportunity PAR-24-272 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity announcement (NOFO) invites applications for the Clinical and Translational Science Award (CTSA) Program hubs that will be part of a national, collaborative consortium focused on bringing more treatments for all people more quickly through advancing clinical and translational science (CTS) by (1) developing, demonstrating, and disseminating scientific and operational innovations that improve the efficiency and effectiveness of clinical translation from identification to first-in-human studies to medical practice implementation to community health dissemination; (2) promoting partnerships and collaborations to facilitate and accelerate translational research projects locally, regionally, and nationally; (3) creating, providing, and disseminating innovative research programs and partnerships across institutions and communities to address health disparities and deliver the benefits of translational science to all; (4) creating and implementing scientific and operational innovations that increase the quality, safety, efficiency, effectiveness, and informativeness of clinical research; (5) providing a national resource for the rapid response to urgent public health needs; and (6) creating, providing, and disseminating CTS training for clinical research professionals of all disciplines on the research team.
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Notice of Early Termination of RFA-DK-25-001: Addressing the Impact of Syndemics on the Health of People with HIV and Diseases and Conditions within the Missions of NIDDK and NHLBI (R01 Clinical Trial Optional)
Notice NOT-DK-24-033 from the NIH Guide for Grants and Contracts
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Notice of Change to Key Dates for PAR-24-270: ADRD Risk and Disease Following Nervous System Exposures at Biological Interfaces with the Environment (R01 - Clinical Trial Not Allowed)
Notice NOT-NS-24-131 from the NIH Guide for Grants and Contracts
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HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
Funding Opportunity RFA-AT-25-001 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.
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Notice of Change to Key Dates Listed in RFA-AG-25-025, "Short Courses Promoting Cross-National Analyses Using Data from the International Health and Retirement Study (HRS) and Harmonized Cognitive Assessment Protocol (HCAP) R25 Clinical Trial Not Allowed"
Notice NOT-AG-24-064 from the NIH Guide for Grants and Contracts
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