Funding Opportunity RFA-AT-19-011 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications for continuation of a Coordinating Center to provide national leadership for the NIH Health Care Systems (HCS) Research Collaboratory program, and specifically to expand its role to include oversight and coordination of trials funded via the Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing FOA.

Funding Opportunity RFA-AR-20-003 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose preclinical studies to advance the development of biomarkers or treatments for rare musculoskeletal, rheumatic or skin diseases. Rare diseases have a prevalence of fewer than 200,000 affected individuals in the United States. Also eligible for potential funding through this initiative are studies of FDA-designated orphan products for musculoskeletal, rheumatic or skin diseases.

Notice NOT-EY-19-026 from the NIH Guide for Grants and Contracts

Notice NOT-AG-19-019 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AR-20-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications that propose to conduct time-sensitive mechanistic ancillary studies related to the NIAMS mission in conjunction with privately or publicly funded, ongoing clinical projects. The ongoing parent clinical project can be an interventional clinical trial, or a clinical study such as an observational study that will be actively collecting patient samples or clinical data. The parent project(s) should provide a cohort of well-characterized patients, infrastructure, data, and biological samples for the ancillary study. Applications submitted in response to this FOA will undergo an accelerated review and award process. The objective of this FOA is to provide a flexible mechanism to leverage established resources and maximize the return on existing investments in parent projects. Successful ancillary studies will enhance the scientific content and value of the parent projects, improve the research communitys understanding of a disease or organ system in the NIAMS portfolio, and thus may identify novel targets for diagnosis, treatment, and prevention of disease.

Funding Opportunity RFA-AR-20-002 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications that propose to conduct time-sensitive mechanistic ancillary studies related to the NIAMS mission in conjunction with privately or publicly funded, ongoing clinical projects. The ongoing parent clinical project can be an interventional clinical trial, or a clinical study such as an observational study that will be actively collecting patient samples or clinical data. The parent project(s) should provide a cohort of well-characterized patients, infrastructure, data, and biological samples for the ancillary study. Applications submitted in response to this FOA will undergo an accelerated review and award process. The objective of this FOA is to provide a flexible mechanism to leverage established resources and maximize the return on existing investments in parent projects. Successful ancillary studies will enhance the scientific content and value of the parent projects, improve the research communitys understanding of a disease or organ system in the NIAMS portfolio, and thus may identify novel targets for diagnosis, treatment, and prevention of disease.

Notice NOT-ES-19-014 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-261 from the NIH Guide for Grants and Contracts. The NICHD has a state-of-the-art Chemical Synthesis and Optimization Facility for advancing male and/or female non-hormonal contraception developmentwith the capabilities and capacity for preclinical services including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies (e.g., protein generation, high throughput screening, structure activity relationships, hit-to-lead generation, drug metabolism, fertility studies). The purpose of this FOA is to provide investigators with a mechanism to request services from this facility that would advance their development program for either male or female contraceptives.

Funding Opportunity RFA-DA-20-005 from the NIH Guide for Grants and Contracts. The purpose of this limited competition Funding Opportunity Announcement (FOA) is to support the maintenance and expansion of existing NIDA-funded cohorts to continue addressing new emerging and/or high priority research on multidisciplinary aspects of HIV/AIDS and substance abuse in alignment with NIH-HIV research priorities.

Notice NOT-HD-19-014 from the NIH Guide for Grants and Contracts

Notice NOT-DE-19-007 from the NIH Guide for Grants and Contracts

Notice NOT-EY-19-028 from the NIH Guide for Grants and Contracts

Notice NOT-EY-19-027 from the NIH Guide for Grants and Contracts

Notice NOT-AG-19-017 from the NIH Guide for Grants and Contracts

Notice NOT-DE-19-006 from the NIH Guide for Grants and Contracts

Notice NOT-OD-19-106 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-260 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity announcement (FOA) is to fund meritorious vision-related research projects that involve secondary data analyses using existing database resources. The development of statistical methodology necessary for improving methods to analyze vision health data using existing vision data may also be proposed.

Notice NOT-HL-19-696 from the NIH Guide for Grants and Contracts

Notice NOT-CA-19-047 from the NIH Guide for Grants and Contracts

Notice NOT-HS-19-014 from the NIH Guide for Grants and Contracts