Funding Opportunity RFA-AA-23-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks applications for research center grants to conduct high-impact research on alcohol and HIV/AIDS. Through this NOFOA, NIAAA seeks to encourage research applications aimed to address the impact of alcohol use (and related other substance use, mental health, and pharmacological/medication complications) on the most important challenges for controlling and ending HIV/AIDS pandemic. This announcement reflects the high priority topics for research described in the NIH Office of AIDS Research FY2021-FY2025 Strategic Plan for HIV and HIV-Related Research https://www.oar.nih.gov/sites/default/files/NIH_StrategicPlan_FY2021-2025.pdf and research aspects included in the National HIV/AIDS Strategy (2022-2025) https://www.hiv.gov/federal-response/national-hiv-aids-strategy/national-hiv-aids-strategy-2022-2025 focused on ending the HIV epidemic among substance users (c.f. alcohol and drug). In particular, translational studies of alcohol use as a risk factor impacting HIV prevention, treatment effectiveness, and HIV-related comorbidities are strongly encouraged.

Funding Opportunity RFA-MD-24-001 from the NIH Guide for Grants and Contracts. The purpose of the Research Centers in Minority Institutions (RCMI) Program is to expand the national capacity for research in the health sciences by providing cooperative agreement support to institutions that offer doctorate degrees in the health professions or in a health-related science and have a documented historical and current mission or historical commitment to educating underrepresented students, and for institutions that provide clinical services to medically underserved communities. The primary goals of RCMI specialized center awards are to: (1) enhance institutional research capacity to conduct world-class basic biomedical, behavioral, population and/or clinical research; (2) enable all levels of investigators at the recipient institution to become more successful in obtaining competitive extramural support, especially from NIH, for research on diseases and conditions that disproportionately impact populations that experience health disparities; (3) foster institutional environments conducive to research career development and enhancement for post-doctoral fellows, junior faculty, and other early-stage investigators; (4) enhance the tools for and conduct of research generally and specifically for improving minority health and reducing health disparities; and (5) establish sustainable partnerships with community-based organizations to promote research efforts and the dissemination of research findings.

Notice NOT-CA-23-096 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-112 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-24-030 from the NIH Guide for Grants and Contracts. The goal of this NOFO is to support the development and application of innovative ex-vivo imaging methods, along with necessary tissue procurement, processing and computation pipelines, to enable the spatial analysis and molecular annotation of intercellular interactions in CNS HIV infection, persistence, and associated neuropathology.

Notice NOT-DE-24-005 from the NIH Guide for Grants and Contracts

Notice NOT-DE-24-004 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-092 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-011 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-CA-24-006 from the NIH Guide for Grants and Contracts. Through this Notice of Funding Opportunity Announcement (NOFO), the National Cancer Institute (NCI) intends to expand the research scope and leverage the gains made through the NOFO entitled Investigation of the Transmission of KSHV (RFA-CA-18-013 and RFA-CA-20-046) to support basic and translational research that will guide the development of a prophylactic or therapeutic Kaposi sarcoma herpesvirus (KSHV) vaccine. A prophylactic KSHV vaccine could prevent primary KSHV infection, transmission, and subsequent development of KS and other KSHV-associated syndromes such as multicentric Castleman disease (MCD), primary effusion lymphoma (PEL) and KSHV inflammatory cytokine syndrome (KICS) or ameliorate the severity of disease. A therapeutic KSHV vaccine could be helpful in preventing or treating KSHV disease in people who are already infected with KSHV. Research areas could include, but are not limited to: (1) Identification and evaluation of KSHV structural and non-structural targets for a potential KSHV vaccine; (2) Development of animal models to study a prototype KSHV vaccine or vaccines; (3) Development and testing of a candidate KSHV vaccine or vaccines; (4) Studies to assess how the efficacy of a promising KSHV vaccine can be optimized for PWH; (5) Research to better define the initial steps of infection with KSHV and the primary means of person-to-person transmission in different populations that can be targeted with a vaccine; and (6) Optimization and/or standardization of KSHV detection methods.

Notice NOT-AI-24-001 from the NIH Guide for Grants and Contracts

Notice NOT-HL-23-118 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-304 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative and interdisciplinary research teams focused on clinical, health services, and/or community-based interventions that address health and healthcare disparities related to non-communicable and chronic diseases (NCDs) with the highest burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multidisciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.

Funding Opportunity PAR-23-303 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) will support innovative, collaborative, and multi-disciplinary research focused on clinical epidemiology, evaluation of public and/or health care policies, and validation of measurements that address health and health care disparities related to non-communicable and chronic diseases (NCDs) with the highest disease burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multi-disciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.

Notice NOT-DA-23-040 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-003 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-072 from the NIH Guide for Grants and Contracts

Notice NOT-EY-24-001 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-028 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites qualified academic or research institutions to apply for funding support to purchase latest equipment that will enhance and modernize research-supporting operations of existing shared biomedical research facilities. Targeted are laboratory research core facilities, animal research facilities, and other similar shared-use research spaces. The goal of this NOFO is to strengthen research-auxiliary activities of biomedical research facilities and to enhance the efficiency of their operations. The NOFO does not support the purchase of scientific research instruments or their components, nor components of building-level infrastructure equipment that indirectly support research activities.

Notice NOT-AI-23-071 from the NIH Guide for Grants and Contracts