Funding Opportunity RFA-CA-23-039 from the NIH Guide for Grants and Contracts. Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for Human Tumor Atlas (HTA) Research Centers, one of the three scientific components of the Human Tumor Atlas Network (HTAN) (NCI Human Tumor Atlas Network). HTAN is a collaborative research initiative for constructing 3-dimensional(3D) and dynamic atlases of the cellular, morphological, molecular, and spatial features of human cancers and their surrounding microenvironments as they progress from precancerous lesions to advanced disease.Each HTA Research Center will construct one human precancer or advanced cancer atlas with an explicit focus on how evolving spatial relationships contribute to important transitions in cancer from tumor initiation to metastasis.The other two HTAN components are Precancer Atlas (PCA) Research Centers and a Data Coordinating Center (DCC). Each PCA Research Center will construct one 3D precancer atlas that comprehensively characterizes a premalignant lesion with an explicit focus on understanding the transition from a precancerous lesion to malignancy.The DCC will serve the dual role of network and data coordination. It will also be responsible for meeting coordination.Research Centers have three major areas of responsibility: (1) biospecimen acquisition, processing, and annotation, (2) molecular, cellular, and spatial characterization, and (3) data processing, analysis, modeling, and visualization.

Funding Opportunity RFA-CA-23-040 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for Precancer Atlas (PCA) Research Centers, one of the three scientific components of the Human Tumor Atlas Network (HTAN) (https://humantumoratlas.org/).HTAN is a collaborative research initiative for constructing 3-dimensional(3D) and dynamic atlases of the cellular, morphological, molecular, and spatial features of human cancers and their surrounding microenvironments as they progress from precancerous lesions to advanced disease.Each PCA Research Center will construct one 3D precancer atlas that comprehensively characterizes a pre-malignant lesion with an explicit focus on understanding the transition from a precancerous lesion to malignancy. The other two HTAN components are Human Tumor Atlas (HTA) Research Centers and a Data Coordinating Center (DCC).Each HTA Research Center will conduct research to develop onespatial tumor atlas at single-cell resolution driven by specific topics in cancer biology across the continuum from cancer initiation to metastasis.

Notice NOT-AG-23-058 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-222 from the NIH Guide for Grants and Contracts. The purpose of the Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award to Promote Diversity (F99/K00) program is to support promising, late-stage graduate students from diverse backgrounds (e.g., see Notice of NIHs Interest in Diversity) to transition into and succeed in mentored postdoctoral research positions. It is anticipated that successful completion of this phased award program will position ARC scholars to advance in impactful careers in the biomedical research workforce that typically require postdoctoral training (e.g., academic research and teaching at a range of institution types, industry or government research). This two-phase award will provide support for late-stage graduate students pursuing research related to the mission areas of participating NIH Institutes, Centers, and Offices (ICOs) to facilitate the completion of doctoral dissertation projects and research training (F99 phase), and to transition into and succeed in postdoctoral biomedical research and career development opportunities (K00 phase). ARC F99 fellows/K00 scholars will be part of organized cohorts and will be expected to participate in mentoring, networking, and professional development activities coordinated by ARC Institutionally-Focused Research Education Award to Promote Diversity (UE5) recipients.

Funding Opportunity PAR-23-221 from the NIH Guide for Grants and Contracts. The overarching goal of the ARC UE5 program is to provide ARC F99 fellows/K00 scholars with professional skills and the appropriate mentoring and networks to allow them to transition into and succeed in postdoctoral research and career development opportunities, positioning them to advance in impactful careers in the biomedical research workforce that typically require postdoctoral training (e.g., academic research and teaching at a range of institution types, industry or government research). To accomplish the stated over-arching goal, this Notice of Funding Opportunity will support evidence-informed educational activities with a primary focus on courses for skills development and mentoring activities.

Notice NOT-HD-23-033 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-039 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-005 from the NIH Guide for Grants and Contracts

Notice NOT-HL-23-091 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-192 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-24-032 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to encourage clinical research that will identify and validate novel targets for non-invasive brain stimulation (NIBS) and SUD-relevant neurobiological, cognitive, and behavioral responses to NIBS that precede clinical outcomes like reduced craving or drug use. This NOFO uses an R01 activity code to support applications that propose mechanistic studies designed to understand a behavior or biological process, the pathophysiology of a disease, or the mechanism of action of an intervention. In addition, applications must meet the NIH definition of a clinical trial. NIH defines a clinical trial as A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes. (NOT-OD-15-015) This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.

Funding Opportunity RFA-DA-24-033 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to encourage clinical research that will identify and validate novel targets for non-invasive brain stimulation (NIBS) and SUD-relevant neurobiological, cognitive, and behavioral responses to NIBS that precede clinical outcomes like reduced craving or drug use. Applications are expected to be exploratory and developmental in nature. As such, these studies may involve considerable risk of failure but may lead to a breakthrough in a particular area that could have a major impact on SUD research involving NIBS. This NOFO uses a R61/R33 Phased Innovation award activity code to support applications that propose mechanistic studies designed to understand a behavior or biological process, the pathophysiology of a disease, or the mechanism of action of an intervention. In addition, applications must meet the NIH definition of a clinical trial. NIH defines a clinical trial as A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes. (NOT-OD-15-015)

Notice NOT-DA-23-033 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-070 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-032 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-031 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-094 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-030 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-029 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-028 from the NIH Guide for Grants and Contracts