Funding Opportunity RFA-DA-24-025 from the NIH Guide for Grants and Contracts. There are many opportunities to leverage the potential of AI/ML to accelerate the pace of biomedical innovation, while prioritizing and addressing health disparities and inequities and mutually beneficial partnerships can be established to increase the participation of underrepresented researchers and communities. It is critical to provide support for meritorious research, strengthen the research environments and collaborations for successful data science projects, and expose undergraduate and/or graduate students in such environments to meritorious research in this area.

Notice NOT-NS-24-008 from the NIH Guide for Grants and Contracts

Notice NOT-NR-23-018 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-307 from the NIH Guide for Grants and Contracts. Reissue of PAR-21-263 to comply with DMS Policy. This Notice of Funding Opportunity (NOFO) solicits proposals for research projects that will use computational approaches to test the validity of dimensional constructs in the NIMH Research Domain Criteria matrix (or similar constructs based on comparable criteria). Some elements of the RDoC matrix have been updated since its first release, but a thorough data-driven validation that broadly explores, compares, and validates the constructs within the matrix has not been performed. This NOFO seeks research that addresses the following questions: do the different domains of behavior segregate from each other? How much do they rely on distinct vs. overlapping neural circuits? What are the relationships between domains, constructs and subordinate subconstructs, both in terms of their correlational structure and their underlying neural circuitry? By answering these questions, proposals will test integrative models of functioning and identify dysregulation in psychopathology-related mechanisms that may cut across traditional diagnostic categories and may change over time. This NOFO seeks to promote projects where the computational and the experimental components are well-integrated. The ultimate goal is to advance translational research that will identify novel classification approaches and/or treatment targets, and lead to more effective and timely interventions for serious mental illness.

Funding Opportunity PAR-23-305 from the NIH Guide for Grants and Contracts. Reissue of RFA-MH-21-264 to comply with DMS Policy . This Funding Opportunity Announcement (FOA) solicits proposals for research projects that will apply computational approaches to develop parametrically detailed behavioral assays across mental-health relevant domains of function. These projects should focus on behavior in humans and test computational models in healthy subjects. For future applications, NIMH is particularly interested in behavioral measures, models, and parameters that have the potential for back-translation from humans to animals, especially for pre-clinical therapeutics development. NIMH is also interested in models that can be extended to clinical populations in the future.

Funding Opportunity RFA-EY-23-001 from the NIH Guide for Grants and Contracts. This FOA seeks applications for unique and innovative recording and/or modulation technologies that are in the earliest stage of development, including new and untested ideas that are in the initial stages of conceptualization. Some projects may aim to increase recording or modulation capabilities by many orders of magnitude, while others may aim to improve the precision and selectivity of recording or modulation (also referred to as stimulation, perturbation, or manipulation). A wide range of modalities are appropriate including acoustic, chemical, electrical, magnetic, and optical, as well as the use of genetic tools. Invasive or non-invasive approaches are sought that will enable large-scale recording and/or precise manipulation of neural activity, and that would ultimately be compatible with experiments in humans or behaving animals. Applications are encouraged from any qualified individual, including chemists, physicists, engineers, theoreticians, materials scientists, and others from fields not typically involved with neuroscience research. This FOA requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.

Notice NOT-AI-23-062 from the NIH Guide for Grants and Contracts

Notice NOT-MH-23-385 from the NIH Guide for Grants and Contracts

Notice NOT-MH-23-350 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-182 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-067 from the NIH Guide for Grants and Contracts

Notice NOT-HL-23-111 from the NIH Guide for Grants and Contracts

Notice NOT-HS-23-022 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-180 from the NIH Guide for Grants and Contracts

Notice NOT-EB-23-017 from the NIH Guide for Grants and Contracts

Notice NOT-MH-23-375 from the NIH Guide for Grants and Contracts

Notice NOT-TR-23-026 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-088 from the NIH Guide for Grants and Contracts

Notice NOT-AT-24-013 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-046 from the NIH Guide for Grants and Contracts