Notice NOT-DA-24-010 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-033 from the NIH Guide for Grants and Contracts

Notice NOT-AT-24-009 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-035 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-197 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to encourage institutions to propose creative and innovative institutional research career development programs which will prepare clinically trained vision scientists for independent research careers. This NOFO is intended to expand and strengthen the community of clinician investigators engaged in vision research. This Notice of Funding Opportunity (NOFO) allows the appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator as part of their research and career development program. For this career development program scholars are limited to clinical trials that are minimal risk. The existing clinical trial must be a NIH-defined clinical trial that fulfills the NIH requirement for minimal risk trial. A minimal risk trial is one in which the probability and magnitude of harm or discomfort anticipated in the research are not greater in and of themselves than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests. Applicants are strongly advised to consult with NEI program staff prior to submitting an application with human subjects to determine the appropriate funding opportunity. For the purposes of this announcement, institutions are highly encouraged to recruit prospective PIs/PDs, mentors, and scholars from underrepresented racial and ethnic groups as well as individuals with disabilities as described in the NOT-OD-22-019 in all of its programs.

Notice NOT-DE-23-002 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-018 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-178 from the NIH Guide for Grants and Contracts. This NIH Neuroscience Development for Advancing the Careers of a Diverse Research Workforce (R25) is a flexible and specialized program designed to foster the development of neuroscience researchers from diverse backgrounds, including from underrepresented groups across career stages. Thus, it encourages applications from applicant organizations that propose innovative mentoring and professional development activities in the mission area(s) of the NINDS and/or NIMH. This Neuroscience Diversity R25 initiative will focus on factors that have been shown to affect retention of underrepresented graduate students, postdoctoral trainees, and junior faculty in neuroscience research such as mentoring, scientific networks, professional development, and attention to the structural and institutional environment regarding inclusion (http://acd.od.nih.gov/dbr.htm; Structure and Belonging: Pathways to Success for Underrepresented Minority and Women Ph.D. Students in STEM Fields; The Science of Effective Mentorship in STEMM).The NIH expects applicant institutions to propose programs that will lead to an improvement in the professional development, mentoring and technical expertise of individuals who are individuals from diverse backgrounds, including those from groups that are nationally underrepresented in neuroscience research. Programs that target transitions and/or more than one career stage for neuroscience career advancement and progression are strongly encouraged. This initiative will support the development of collaborative research education partnerships that will increase participants awareness and interest in the neurosciences, develop participants scientific knowledge and research skills that will allow them to progress and transition to more advanced neuroscience-related research education and training activities. Proposed program interventions to enhance workforce diversity in response to this FOA should also focus on asset models and leadership opportunities, rat

Notice NOT-HS-23-014 from the NIH Guide for Grants and Contracts

Notice NOT-DK-23-023 from the NIH Guide for Grants and Contracts

Notice NOT-DK-23-024 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AG-24-047 from the NIH Guide for Grants and Contracts. The goal of the Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) program is to provide support for early-career physician-scientists trained in medical or surgical specialties and early-career dentist-scientists to launch careers as future leaders in aging- or geriatric-focused research. In support of the program's goal, this GEMSSTAR NOFO provides small grants to conduct transdisciplinary aging research that will yield pilot data and experience for subsequent aging research projects.

Funding Opportunity RFA-AI-23-038 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the development of software to improve the acquisition, management, analysis, visualization, and dissemination of data and knowledge for data science research on infectious and immune-mediated diseases (IID). Relevant IID data science research comprises, but is not limited to, computational methods to better understand disease mechanism, risk prediction, epidemiology, detection and diagnosis, treatment, and vaccines, aligned with the research mission of NIAID. Development of software in various stages of maturity will be in scope for this FOA, ranging from early-stage prototyping to later-stage hardening. Early-stage prototyping will enable others to use new computational algorithms, tools, or technologies through easy-to-use software products while hardening of existing software could improve usability and enable a broader user base to use the software for their research. Regardless of the development stage, the proposed work should result in a software product that can be re-used by the IID research community and that can be easily discovered through FAIR (Findable, Accessible, Interoperable and Reusable) compliant metadata.

Notice NOT-OD-23-140 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-23-027 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to: improve the understanding of the roles and interactions of immune cells at the maternal-fetal interface that support pregnancy and enable optimal placental development and function; and elucidate the mechanisms by which infection, vaccination, or environmental perturbations during gestation modulate immune responses in the pregnant individual and alter systemic or tissue-specific immunity in the offspring.

Funding Opportunity RFA-AG-24-037 from the NIH Guide for Grants and Contracts. The purpose of this limited competition Request for Applications (RFA) is to continue data collection, development, and dissemination of the National Health and Aging Trends Study (NHATS) and National Study of Caregiving (NSOC). Continuation of the study requires both knowledge of, and access to, the NHATS and NSOC sample frames. Therefore, this RFA is limited to investigators and institutions with access to the NHATS and NSOC sample frame, as the frame will be used to contact and collect new data from participants. This RFA aims to provide additional research opportunities to use NHATS to formally study disability and Alzheimers disease (AD) and AD-related dementias (ADRD). This single integrated award combining NHATS and NSOC seeks to implement the comments of the NHATS Data Monitoring Committee to include continued the core elements of NHATS/NSOC and expand content to include enhanced cognitive/dementia measures, new sensory measures, richer dementia care measures, life course measures to capture sources of health disparities, improved residential care data, and an expanded accelerometry sample to facilitate AD/ADRD research that could enhance research targeting related NIA Dementia Care Milestones. Applicants are required to submit a Letter of Support from their institution confirming that they have access to personally identifiable information about NHATS and NSOC panel members and the ability to contact study participants for longitudinal follow-up and administrative/program data linkage.

Notice NOT-AT-24-008 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AT-24-003 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) intends to support the development of innovative methods for quantitative evaluation of myofascial tissues for pain management involving research participants using a two-phase grant funding mechanism. This effort is part of the NIH HEALSM (Helping to End Addiction Long-term) Initiative to speed the development and implementation of scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative is bolstering research across NIH to (1) improve treatment and prevention of opioid misuse and opioid use disorder and (2) enhance pain management. This notice of funding opportunity (NOFO) seeks research applications to develop quantitative measures of myofascial tissues and assess their abilities to detect changes to myofascial tissues across a variety of pain management interventions. Candidate objective measures may be based on minimally invasive imaging technologies, electrophysiological recordings, integration of multiparametric imaging and electrophysiology approaches, or their integration with other markers (e.g., immune factors, genomic markers, physiological factors) through multiscale modeling or machine learning analysis. The first phase, funded by the R61, will provide funding for up to 3 years to develop quantitative measures that can differentiate abnormal myofascial tissue from healthy tissues using cross-sectional correlations with clinical signs/symptoms. In addition, the R61 phase should include planning activities for the R33 phase. The second phase, funded under the R33, will provide support to assess the abilities of the quantitative measures developed in the R61 phase to measure tissue changes in response to therapies or manipulations that may relieve pain using rigorous, longitudinal clinical study design. The combined R61/R33 should not exceed 5 years. Transition from the R61 to the R33 phase of the award will be administratively reviewed and will be determined based on successful co

Funding Opportunity RFA-AG-24-026 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites R34 applications to support the planning activities necessary to develop social network interventions to promote health across the lifespan, especially in populations in which they are currently largely underdeveloped and untested (such as populations in mid- and late-life). Applications suited to this R34 will focus on planning activities for social network interventions for which a target interpersonal process of behavior change or social network characteristic has already been identified. Planning activities are those activities that are expected to yield necessary and sufficient information to inform final decisions about a social network health behavior change intervention prior to instigation of a hypothesis-driven trial to test a social network intervention. Activities may include (but are not limited to) team-building, protocol development, piloting of systems for data collection and/or management, feasibility and acceptability testing, staff training, and establishing documentation procedures. Basic experimental and observational behavioral and/or social science applications that test how intrapersonal and interpersonal mechanisms of behavior change interact with, influence, or are influenced by characteristics of social networks are outside the scope of this RFA. Research to identify targets for future social network health behavior change interventions and/or to develop, refine, or optimize measures (assays) of putative targets are also outside the scope of this RFA. Both of these types of research are most appropriate for the companion R01 RFA (RFA-AG-24-025). Projects that propose to test the efficacy or effectiveness of a social network health behavior change intervention are also outside the scope of this RFA, which focuses only on pre-trial planning and development activities.

Funding Opportunity RFA-AG-24-025 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to invite basic observational or experimental behavioral and/or social science R01 applications that test how intrapersonal and interpersonal mechanisms of behavior change interact with, influence, or are influenced by characteristics of social networks, with implications for health. Research supported through this NOFO will examine at least two levels of analysis: interpersonal processes and social network characteristics. Projects will identify targets for future social network health behavior change interventions across the lifespan, especially in populations in which they are currently largely underdeveloped and untested (such as populations in mid- to- late life). Basic research to develop, refine, or optimize measures (assays) of putative targets (e.g., intra/interpersonal mechanisms of behavior change and/or social network characteristics) are also supported by this NOFO. Clinical trials that do not meet the federal definition of basic research (CFR 272.3) are not responsive to this RFA. Projects that propose to support the planning activities necessary to develop social network interventions for which a target has already been identified are most appropriate for the R34 RFA companion (RFA-AG-24-026).