NIH Funding Opportunities (Notices, PA, RFA)

Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 1 hour 22 min ago
Accelerating Behavioral and Social Science through Ontology Development and Use: Research Network Projects (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-182 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications to support research projects focused on the expansion of existing or development of new ontologies for behavioral or social science research (BSSR). The research projects must include multi-disciplinary teams of subject matter experts in one or more BSSR fields, as well as ontology related informatics and computational approaches. Projects should address health-related behavioral and social science problems not easily solved without improvement in semantic knowledge structures (e.g., controlled vocabularies, taxonomies, and ontologies). Each project should identify one or more BSSR use cases and elucidate how the proposed ontological resources or tools to be developed and tested will advance BSSR research capabilities and efficiencies. This includes a plan for promoting dissemination and use of the resources and tools. Tools or resources proposed should include health-relevant terminology related to constructs, measures, and/or intervention components. Tools or resources must also account for socio-behavioral cultural context in vocabulary/ontology development. As part of a cooperative agreement, each project will focus on independent ontology development research aims and be expected to work collaboratively with the Dissemination and Coordination Center (DCC; PAR-23-181) and the other funded projects in a Behavioral and Social Science Ontology Development U01 Research Network.
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Accelerating Behavioral and Social Science through Ontology Development and Use: Dissemination and Coordination Center (U24) Clinical Trial Not Allowed
Funding Opportunity PAR-23-181 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications from multi-disciplinary teams to establish a Dissemination and Coordination Center (DCC) for the Behavioral and Social Science Ontology Development U01 Research Network Projects (PAR-23-182). Teams must include subject matter experts in 1) one or more fields of behavioral or social science, 2) ontology-related informatics and computational approaches, and 3) Team Science or the Science of Science. The primary responsibilities of the DCC are to: 1) Coordinate and provide logistical support to facilitate collaboration and cross-project learning; 2) Provide ontology-related technical, computational, and informatics expertise and support; 3) Facilitate dissemination of resources and training to support ontology expansion, development, and use; and 4) Provide active outreach and coordination with relevant stakeholders to increase understanding of and demand for BSSR ontology-related tools and resources.
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Notice of Change to Receipt Dates in RFA-AG-24-017, "Limited Competition: Renewal of the Longevity Consortium (U19 Clinical Trial Not Allowed)"
Notice NOT-AG-23-025 from the NIH Guide for Grants and Contracts
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Updated Notice of Information for HIV research priorities at the National Heart, Lung, and Blood Institute
Notice NOT-HL-23-088 from the NIH Guide for Grants and Contracts
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Request for Information on Religion, Spirituality, and Alcohol Research Aims
Notice NOT-AA-23-008 from the NIH Guide for Grants and Contracts
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Notice of Intent to Publish a Notice of Funding Opportunity for the HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies) Pain Program Resource and Data Center (U24 Clinical Trial Not Allowed)
Notice NOT-HD-23-016 from the NIH Guide for Grants and Contracts
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Notice of Intent to Publish a Notice of Funding Opportunity for the HEAL Initiative: KIDS Acute Pain Clinical Trials (APCT) Program (U01 Clinical Trial Required)
Notice NOT-HD-23-015 from the NIH Guide for Grants and Contracts
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Comprehensive Alcohol Research Centers (P60 Clinical trial Optional)
Funding Opportunity RFA-AA-23-002 from the NIH Guide for Grants and Contracts. This FOA uses the NIH Comprehensive Research Center (P60) mechanism to support an integrated, broad-based multidisciplinary, multi-investigator, long-term program of research and research support activities planned around a specific major research theme.
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Specialized Alcohol Research Centers (P50 Clinical trial Optional)
Funding Opportunity RFA-AA-23-001 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications for specialized Alcohol Research Centers using the P50 mechanism. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol use disorder, alcohol-related end organ diseases and their biomedical, psychosocial, and economic consequences across the lifespan and racial/ethnic groups and other health disparity populations. Centers also are regional or national resources that contribute to the development of new research methods, technologies and approaches that sustain innovative goal-directed research.
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Investigating Distinct and Overlapping Mechanisms in TDP-43 Proteinopathies, including in LATE, FTD and other ADRDs (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-23-212 from the NIH Guide for Grants and Contracts. This FOA would support establishing deeper mechanistic insight and causal relationships between TDP-43 pathology and phenotypic outcomes, as well as mechanistic interactions between TDP-43 and other co-pathologies, such TMEM106B. Additionally, it would include comparisons (including mechanistic, molecular, structural, cellular, genetic, -omic, anatomical, neuropathological, etc.) between TDP-43 proteinopathies, including LATE, with or without AD-NC, and FTD and/or ALS.
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Mechanistic Investigations into ADRD Multiple Etiology Dementias (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-23-211 from the NIH Guide for Grants and Contracts. This FOA would support investigations with a minimum of two relevant co-pathologies (e.g., tau, alpha-synuclein, TDP-43, TMEM106B, vascular), with optional risk factors and co-morbidities, to identify cellular and molecular mechanisms of how/why multi-proteinopathy interactions drive worsening neurodegenerative processes and phenotypic outcomes. Studies should examine co-pathology cellular and molecular interactions across brain regions and time in proximate cell population, across various intracellular dynamics and localization, and upstream and downstream from aggregated protein states to determine what events lead to worse phenotypic outcomes.
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NIMHD Centers of Excellence in Investigator Development and Community Engagement (P50 - Clinical Trial Optional)
Funding Opportunity RFA-MD-23-011 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to further advance NIMHDs mission by supporting Centers of Excellence to enhance research training and education of academic faculty (including post-doctoral fellows, junior faculty, and other early-stage investigators) in the conduct of minority health and health disparities research.
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Field-Deployable, Low-Cost Point-of-Need Approaches and Technologies to Lower the Barriers to Substance Use Disorders (SUD) Diagnosis and Treatment (R43/R44 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-018 from the NIH Guide for Grants and Contracts. The FOA intends to spur the development of cost-effective technologies that may reduce or even eliminate disparities in SUD treatment. Disparities due to geographical access or rural/urban divide, due to treatment cost, or due to stigma will be specifically targeted. The intention is to bring to the treatment to the patient, not the patient to the treatment.
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Field-Deployable, Low-Cost Point-of-Need Approaches and Technologies to Lower the Barriers to Substance Use Disorders (SUD) Diagnosis and Treatment (R41/R42 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-017 from the NIH Guide for Grants and Contracts. The FOA intends to spur the development of cost-effective technologies that may reduce or even eliminate disparities in SUD treatment. Disparities due to geographical access or rural/urban divide, due to treatment cost, or due to stigma will be specifically targeted. The intention is to bring to the treatment to the patient, not the patient to the treatment.
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Notice of Change to Application and Submission Information for RFA-NS-23-026 "BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)"
Notice NOT-NS-23-086 from the NIH Guide for Grants and Contracts
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Limited Competition for the NIDDK Short-Term Research Experience Program to Unlock Potential (STEP-UP) (R25 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-22-510 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research.
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Notice of Special Interest (NOSI): Intersectional Stigma and Discrimination (ISD), or Other Social and Structural Determinants of Health (SSDOH) in HIV Prevention and Treatment
Notice NOT-MH-23-270 from the NIH Guide for Grants and Contracts
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Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-193 from the NIH Guide for Grants and Contracts. The NICHD has a state-of-the-art Chemical Synthesis and Optimization Facility for advancing both non-hormonal contraceptive and reproductive health related product development. This facility has the capabilities and capacity for preclinical services including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies (e.g., protein generation, X-ray crystallography, high throughput screening, structure activity relationships, hit-to-lead generation, drug metabolism). The long-term objective is to enable a preclinical candidate for IND/IDE study(ies) that offers a safe therapeutic option in the field of contraception, and/or reproductive health related indications (pending contractor availability and available funding).
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Notice of Change to RFA-AG-24-009, "Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) Real-World Data Platform (U54 Clinical Trial Optional)"
Notice NOT-AG-23-028 from the NIH Guide for Grants and Contracts
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Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults
Notice NOT-MH-23-250 from the NIH Guide for Grants and Contracts
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