Notice NOT-NS-23-071 from the NIH Guide for Grants and Contracts

Notice NOT-TR-23-021 from the NIH Guide for Grants and Contracts

Notice NOT-CA-23-070 from the NIH Guide for Grants and Contracts

Notice NOT-TR-23-020 from the NIH Guide for Grants and Contracts

Notice NOT-HL-23-089 from the NIH Guide for Grants and Contracts

Notice NOT-RM-23-014 from the NIH Guide for Grants and Contracts

Notice NOT-RM-23-015 from the NIH Guide for Grants and Contracts

Notice NOT-RM-23-016 from the NIH Guide for Grants and Contracts

Notice NOT-RM-23-017 from the NIH Guide for Grants and Contracts

Notice NOT-DK-23-029 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DK-23-008 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement will provide support for a Human Islet Research Enhancement Center that will supply the infrastructure needed to support research coordination, collaboration and dissemination of advances made by the NIDDK funded Human Islet Research Network (HIRN).

Funding Opportunity PAR-23-199 from the NIH Guide for Grants and Contracts. NIH established a clinical genomics infrastructure to develop an openly accessible knowledgebase that promotes data sharing and provides standardized infrastructure and tools for determining the clinical relevance of genetic variants through two initiatives: the Clinical Genomics Resource (ClinGen) and the Clinical Variant Database (ClinVar) of clinical variation. ClinGen defines the clinical relevance of genes and variants for use in precision medicine and research by standardizing clinical annotation and interpretation of variants and implementing evidence-based expert consensus assertions. The purpose of this Notice of Funding Opportunity (NOFO) is to establish Expert Panels that will select genes and genomic variants associated with diseases or conditions of high priority to participating NIH Institutes and Centers (ICs) and systematically determine their clinical significance for diagnosis and treatment of these diseases or conditions. The Genomic Curation Expert Panels funded through this NOFO are required to utilize the NHGRI Clinical Genomics Resource (ClinGen) and the NCBI ClinVar procedures, interfaces, tools, and informatics infrastructure.

Notice NOT-HD-23-017 from the NIH Guide for Grants and Contracts

Notice NOT-NS-23-070 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-214 from the NIH Guide for Grants and Contracts. "This FOA will solicit R01 applications that propose studies in animal, cell culture, and/or human tissue models to elucidate the mechanisms by which COVID-19 interacts with and/or modulates AD/ADRD-relevant phenotypes. Either the model itself or the experimental readouts will be required to incorporate AD/ADRD risk factors, pathologies, or relevant comorbidities. To this end, proposals can focus on one or more of the following: - Mechanistic studies that address how COVID-19 impacts CNS pathology and cognitive outcomes when AD/ADRD pathology is already present (for example, in a model of AD/ADRD). - Mechanistic studies that address how COVID-19 accelerates AD/ADRD pathology and cognitive deficits in a prodromal model (early phase, pre-symptomatic). - Mechanistic studies that address how COVID-19 predisposes for AD/ADRD and/or interacts with relevant comorbid conditions and risk factors (cellular mechanisms that could potentially increase the risk for future AD/ADRD)."

Notice NOT-MH-23-275 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-HG-23-017 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support investigator-initiated research in genomics and health equity, with the ultimate goal of developing approaches, generating and disseminating data, and implementing metrics or interventions that will advance the equitable use of genomics to improve health in U.S. populations. Awardees will conduct innovative and generalizable research in genomics and health equity spanning across NHGRIs scientific areas and will incorporate a plan for strategies to facilitate inclusive and diverse perspectives. Applications from New or Early Stage Investigators from diverse backgrounds are encouraged.

Funding Opportunity RFA-HG-23-018 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support investigator-initiated research in genomics and health equity, with the ultimate goal of developing approaches, generating and disseminating data, and implementing metrics or interventions that will advance the equitable use of genomics to improve health in U.S. populations. Awardees will conduct innovative and generalizable research in genomics and health equity spanning across NHGRIs scientific areas and will incorporate a plan for strategies to facilitate inclusive and diverse perspectives. Applications from New or Early Stage Investigators from diverse backgrounds are encouraged. This R21 FOA will support small research projects that can be carried out in a short period of time with limited resources and seeks to facilitate the transition to research independence of diverse New Investigators. The R21 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.

Notice NOT-NS-23-087 from the NIH Guide for Grants and Contracts

Notice NOT-HD-23-012 from the NIH Guide for Grants and Contracts