Notice NOT-GM-23-036 from the NIH Guide for Grants and Contracts

Notice NOT-OD-23-099 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-010 from the NIH Guide for Grants and Contracts

Notice NOT-AG-23-011 from the NIH Guide for Grants and Contracts

Notice NOT-AI-23-033 from the NIH Guide for Grants and Contracts

Notice NOT-TR-23-006 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-24-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications aimed at elucidating neuroimmune and neuronal-glial pathophysiological mechanisms of HIV-associated neurological disorders (HAND) using ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC) in the presence of addictive substances. Specific emphasis is on unbiased, reproducible analysis of genetics and epigenetics, neuroglial interactions, and neuroimmune cell activities from the single cell to neural circuit levels.

Funding Opportunity RFA-AT-24-001 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to support a Research Network that promotes multidisciplinary mechanistic and translational studies of Sickle Cell Disease (SCD) pain. This network is expected to develop compelling research frameworks and model systems that will support interdisciplinary collaborations; initiate pilot projects to test novel mechanistic hypotheses in the high-priority research areas listed below and develop novel technologies and methodologies to study pain in the organ(s) typically impacted by SCD. To accomplish these objectives, applicants can propose activities such as meetings, workshops, conferences, research collaborations, exchange of ideas through visiting scientist arrangements, or training opportunities. These activities will help identify unique research gaps and opportunities that can be addressed through the network in the form of pilot projects which will in turn generate the preliminary data needed for SCD pain investigators to successfully compete for more substantial NIH grants, including The Helping to End Addiction Long-term (HEAL) Initiative grant awards. In addition, the network shall sustain its scientific impact through a variety of dissemination and outreach strategies, including publication of research frameworks, reviews, and other best practices to foster the growth and development of research in priority areas.

Notice NOT-HD-23-005 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AG-24-015 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites early-stage physician and other health professional investigators with a commitment to aging and/or aging-related diseases to apply for this award to advance their research and leadership skills in their specialty and in the broader field of aging and geriatrics research.The National Institute on Aging (NIA) is pursuing this initiative to recruit early-stage investigators who have begun to establish research programs and who, through this award, will be ready to assume leadership roles in their field of expertise and will be poised to change theory, practice, and health outcomes related to the health of older individuals. Unlike other mentored K awards, candidates for this award must have received competitively awarded research support as a Program Director/Principal Investigator (PD/PI) at the faculty level or have otherwise leveraged faculty-level research support to develop an independent line of research. They must show evidence of leadership in the clinical or research domain.

Notice NOT-CA-23-047 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AG-24-014 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites early-stage physicians and other health professional investigators with a commitment to aging and/or aging-related diseases to apply for this award to advance their research and leadership skills in their specialty and in the broader field of aging and geriatrics research.NIA is pursuing this initiative to recruit early-stage investigators who have begun to establish research programs and who, through this award, will be ready to assume leadership roles in their field of expertise and be poised to change theory, practice, and health outcomes related to the health of older individuals. Unlike other mentored K awards, candidates for this award must have received competitively awarded research support as a PD/PI at the faculty level or have otherwise leveraged faculty-level research support to develop an independent line of research. They must show evidence of leadership in the clinical or research domain.

Notice NOT-RM-23-007 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DK-22-037 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) provides support to eligible, domestic institutions to develop and implement Postbaccalaureate Research Education Programs in Diabetes, Endocrinology and Metabolic Diseases (DDEMD). These post-baccalaureate research programs will incorporate extensive research experiences and well-designed courses for skills development to prepare recent college graduates from diverse backgrounds to transition into and complete rigorous, research-focused biomedical doctoral degree programs (e.g., Ph.D. or M.D./Ph.D.). The long-term goal of post-baccalaureate participants admitted to the program should be pursuing a career focused on DDEMD-related research. Eligible applicants for the R25 must be research-intensive doctoral degree-granting institutions with a research base in DDEMD science of at least $3 million in direct costs of peer-reviewed research projects, and research opportunities for students admitted to the program must be in DDEMD science.

Funding Opportunity RFA-MH-23-275 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage research to integrate/harmonize existing large prevention trial data sets implemented earlier in life to examine whether they reduce risk for later suicide, including suicide thoughts and behaviorsfatal and nonfatal (STB), and related external injuries (e.g., nonfatal SUD/OUD/accidents, and all-cause mortality (e.g., National Death Index). This U01 will be competed and funded to: 1) obtain existing prevention trial data sets, with collaboration of the PIs who have the original data sets; 2) anonymize and aggregate and harmonize prevention trial data sets; 3) provide methodological and statistical expertise needed to examine, using theory-based approaches, whether intervening early reduces risk for STB and mortality, and potential mediators and moderators; and 4) oversee a final harmonized prevention trial data that will be deposited into the NIMH Data Archive (NDA). This harmonized dataset will serve as an ongoing resource to the research community for years to come.

Funding Opportunity RFA-NR-23-004 from the NIH Guide for Grants and Contracts. Care delivery, in which a patients health is viewed apart from their social context, must be reimagined to make meaningful improvements in health, eliminate health disparities, and advance health equity. The purpose of the Bridge-to-Care initiative is to promote research that links clinical care with community services and resources to address unmet social needs and adverse social conditions. More specifically, this funding opportunity invites intervention research studies, conducted in partnership with healthcare and community organizations, that address individuals' and families' unmet social needs and communities' adverse social conditions, with a focus on populations that bear an excess burden of morbidity and mortality.

Funding Opportunity RFA-NR-23-002 from the NIH Guide for Grants and Contracts. Disparities in maternal health outcomes is a public health crisis that requires new insights and solutions. The purpose of this initiativeadvancing integrated models (AIM) of careis to stimulate research to develop or evaluate supportive care models that address healthcare access or healthcare quality together with structural or social inequities in order to prevent adverse maternal health outcomes among racial and ethnic minority women. This includes original intervention research and research evaluating the impact of federal, tribal, state, local, or organizational policies and programs on maternal health outcomes. Outcomes of interest include pregnancy-related morbidity (e.g., hypertension, diabetes, obesity, cerebrovascular disease, mental illness) including severe maternal morbidity; pregnancy-associated factors (e.g., violence exposure including firearm violence, substance use disorders, dietary patterns), and maternal mortality.

Funding Opportunity RFA-NR-23-003 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to identify and evaluate the ongoing and long-term impacts of the pandemic era, focusing specifically on governmental (local, state, tribal, federal) policy and programmatic actions that address two specific social determinants of health: food/nutrition security and housing security. Applications are requested to examine how these food/nutrition and housing policies and programs aimed at lessening the effects of the pandemic era impacted health and health equity in individuals, families, and communities from health disparity populations. Health disparity populations include Blacks/African Americans, Hispanics/Latinos, American Indians and Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities.

Notice NOT-OD-23-094 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-23-121 from the NIH Guide for Grants and Contracts. New biologic knowledge will come from both sole investigators following their vision and from teams of scientists sharing their expertise. Some complex biomedical problems require a multidisciplinary vantage point to discover an innovative solution. This Funding Opportunity Announcement (FOA) invites grant applications for investigator-initiated Research Program Project Grant (P01) renewal (Type 2) applications. The P01 program project award supports research that has multiple distinct but synergistic projects built around a unifying central theme within the scientific mission of the NIDDK. The P01 is one of several grant mechanisms the NIDDK uses to foster multi-disciplinary, collaborative research projects. More information on and a comparison among these collaborative grant mechanisms supported by NIDDK can be found at: https://www.niddk.nih.gov/research-funding/process/apply/funding-mechanisms/collaborative-grants-comparison. A central theme or well-defined major objective is the foundation of a P01 program project. Compared to the narrower thrust of a traditional R01 research project, a program project is directed toward a range of scientific questions that elucidate various aspects of the central theme. The interrelationships of research projects and collaborations among investigators will yield synergy and results beyond those achievable if each research project were to be pursued independently. In addition, one or more shared research cores are required. The project leaders and core leaders should be established investigators with strong records of innovative research and independent funding support. The participation of experts in several disciplines or in several areas of one discipline will greatly enhance the goals of the program project. All investigators must contribute to, and share in, the responsibilities of fulfilling the program objectives.