Funding Opportunity RFA-TR-19-014 from the NIH Guide for Grants and Contracts. This FOA invites applications for projects designed to test the effectiveness of microphysiological systems (MPS), also called tissue chip, technology, for clinical trial frameworks by demonstrating their applied use in clinical trial planning and execution, addressing both safety and efficacy in late-stage preclinical studies. This approach is to provide evidence of the utility of tissue chip technology for precision medicine in informing trial design, establishing recruitment criteria and stratification of patient populations in identifying the best responders to candidate therapeutics.

Notice NOT-MH-20-022 from the NIH Guide for Grants and Contracts

Notice NOT-NS-19-058 from the NIH Guide for Grants and Contracts

Notice NOT-NS-19-068 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-MH-20-215 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Institute of Mental Health (NIMH) seeks applications to develop, sustain, enhance, and enrich a centralized national biorepository for genetic studies of psychiatric disorders for facilitation and acceleration of the scientific understanding of the genetic risk architecture underlying mental disorders. This effort is expected to involve a functionally integrated, multi-disciplinary team that will provide for open sharing of biosamples and data resources through a single, centralized, national resource to advance basic and translational research in the genetics of mental disorders.

Funding Opportunity RFA-AG-20-022 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to conduct new research on automobile technology for signaling early signs of cognitive impairment in older drivers.

Notice NOT-MH-19-030 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-297 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks to support collaborative clinical studies, not involving treatment development, efficacy, or effectiveness trials. Primary areas of focus include mental health genetics, biomarker studies, and studies of mental illnesses (e.g., psychopathology, neurodevelopmental trajectories of psychopathology) also when associated with HIV/AIDS. Applicants should apply to this FOA when two or more sites are needed to complete the study. Accordingly, the collaborating studies share a specific protocol across the sites and are organized as such in order to increase sample size, accelerate recruitment, or increase sample diversity and representation. In studies with a large number of sites, it is expected that one site will be submitted as a coordinating R01 for data management and/or other centralized administration.

Notice NOT-CA-19-053 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-295 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages solicits applications that propose research designed to test training, mentoring, and networking interventions intended to enhance research-oriented individuals' interest, motivation, persistence and preparedness for careers in the biomedical research workforce. Funded projects are expected to produce research findings that will guide the design and implementation of potential interventions in a variety of academic settings and career levels to enhance the diversity of the biomedical research workforce.

Notice NOT-OD-19-111 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-296 from the NIH Guide for Grants and Contracts. The NIAID New Innovator Awards supports post-doctoral and early stage investigators of exceptional creativity who propose highly innovative bold new research with the potential to produce a major impact on broad, important problems in biomedical research of priority to NIAID. Applications from individuals with diverse backgrounds and in any topic relevant to the mission of NIAID are welcome.

Notice NOT-NS-19-066 from the NIH Guide for Grants and Contracts

Notice NOT-NS-19-067 from the NIH Guide for Grants and Contracts

Notice NOT-HD-19-016 from the NIH Guide for Grants and Contracts

Notice NOT-DA-19-049 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-HL-20-015 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to invite applications to participate as a Research Center in the Pediatric Cardiac Genomics Consortium (PCGC) (http://www.benchtobassinet.com/). The PCGCs mission is to identify genetic causes of human congenital heart disease (CHD) and to relate genetic variants in patients with CHD to clinical outcomes through collaborative, multi-center studies. The PCGC fosters investigation along the translational spectrum of CHD research through interactions with Cardiovascular Development Data Resource Center (CDDRC, previously the Cardiovascular Development Consortium) and the Pediatric Heart Network (PHN). Together, they constitute the Bench to Bassinet Program (http://www.benchtobassinet.com/ProgramOverview.asp) (B2B). Sites not currently part of the PCGC are encouraged to apply and propose new directions for the consortium.

Funding Opportunity RFA-HL-20-017 from the NIH Guide for Grants and Contracts. The objective of this FOA is to support the development of the Data Resource Center for the basic science component of the NHLBI Bench to Bassinet (B2B) Program. The goal of the Data Resource Center is to accelerate discovery of genetic etiology and biologic pathways associated with cardiovascular development and congenital heart disease by facilitating access to and querying of annotated data from cardiovascular development studies.

Funding Opportunity PAR-19-294 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to support translational research that provides strong justification for later-phase therapeutics discovery and development efforts in health-related outcomes relevant to the National Institute of Diabetes and Digestive and Kidney Diseases. This includes outcomes relevant to obesity, diabetes and related aspects of endocrinology and metabolism, digestive diseases, liver diseases, nutrition, kidney and urological diseases, and hematology. Additional information concerning programmatic areas at NIDDK is available a www.niddk.nih.gov/research-funding/research-programs/Pages/default.aspx and applicants are strongly encouraged to discuss research priorities with the Scientific Contact.

Notice NOT-HL-19-704 from the NIH Guide for Grants and Contracts