Funding Opportunity RFA-AG-20-006 from the NIH Guide for Grants and Contracts. The goal of this initiative is to support research that can lead to the development of interventions for optimizing communication among patients, caregivers, and health care practitioners, and for preserving strong and supportive caregiving relationships throughout disease progression along the continuum of care for people with AD/ADRD. To these ends, basic research and translational research is solicited in two high-priority areas: (1) effective communications and relationships among patients, healthcare practitioners, and caregivers; and (2) associations between close relationship processes and health in caregiving relationships.

Funding Opportunity RFA-AG-20-036 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research applications addressing cellular and molecular mechanisms that regulate aging of the reproductive tissues, including the gonadal niche, in gonads, reproductive accessory organs, and reproductive neuroendocrine system. This FOA will accept basic mechanistic studies in human subjects and vertebrate animals. Research supported by this initiative should enhance knowledge of mechanisms that regulate aging of the reproductive system.

Funding Opportunity PAR-19-292 from the NIH Guide for Grants and Contracts. This FOA is intended to foster research towards a better understanding of the biological mechanisms of gene-environment interplay in human diseases and conditions. Through this FOA, the NIDCR and NIEHS solicit applications that use animal models, in vitro systems, or ex vivo approaches to conduct mechanistic investigation of the interplay of genes/gene networks and environmental factors in dental, oral, craniofacial, and other diseases and conditions.

Funding Opportunity PAR-19-293 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is intended to foster research towards a better understanding of the biological mechanisms of gene-environment interplay in human diseases and conditions. Through this FOA, the NIDCR and NIEHS solicit applications to develop novel and robust experimental systems that offer approaches complementary to human epidemiologic or in vivo studies to facilitate mechanistic investigation of gene-environment interplay in dental, oral, craniofacial, and other diseases and conditions.

Funding Opportunity RFA-RM-19-003 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications from sites not currently part of the Common Fund Enhancing Diversity in the Biomedical Research Workforce initiative, also known as the Diversity Program Consortium (DPC), to expand the national impact of the program. The purpose is to provide funds to institutions to implement DPC scientific approaches to understanding the effectiveness of biomedical research training, mentoring or research capacity building interventions aimed at enhancing diversity in the biomedical research workforce.

Notice NOT-MD-19-024 from the NIH Guide for Grants and Contracts

Notice NOT-TR-19-022 from the NIH Guide for Grants and Contracts

Notice NOT-HG-19-023 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-19-291 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for laboratory-based scientists. The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional scientists who want to continue to pursue research within the context of an existing NCI-funded basic, translational, clinical, or population science cancer research program, but not serve as independent investigators. These non-tenure track scientists, such as researchers within a research program, are vital to sustaining the biomedical research enterprise. It is anticipated that only exceptional scientists who want to pursue research within the context of an existing NCI-funded cancer research program, but not serve as independent investigators, will be competitive for this award.

Funding Opportunity PAR-19-290 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for core/shared resource/central scientific support scientists. The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional scientists who want to continue to pursue research within the context of an existing NCI-funded basic, translational, clinical, or population science cancer research program, but not serve as independent investigators. These scientists, such as researchers within a core/shared resource/central scientific support, are vital to sustaining the biomedical research enterprise. The Research Specialist Award is intended to provide salary support and sufficient autonomy so that individuals are not solely dependent on NCI grants held by others for career continuity.

Funding Opportunity RFA-AG-20-019 from the NIH Guide for Grants and Contracts. This FOA supports applications for Claude D. Pepper Older Americans Independence Centers (OAICs), centers of excellence in geriatrics research and research education to increase scientific knowledge leading to better ways to maintain or restore independence in older persons. The OAIC awards are designed to develop or strengthen awardee institutions programs that focus and sustain progress on a key area in aging research related to the mission of the OAIC program.

Funding Opportunity RFA-HL-20-007 from the NIH Guide for Grants and Contracts. To establish a set of complementary model systems that reproduce essential disease-defining features of human idiopathic pulmonary fibrosis (IPF). This collection of models will advance our understanding of the pathogenesis of IPF from its onset through disease progression and serve as a resource for the broader research community, including investigators developing and testing novel therapies to treat this fatal disease.

Notice NOT-HL-19-705 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-MH-20-140 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. This includes technologies that do not rely on the use of human fetal tissue, as described in NOT-19-042. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states.

Funding Opportunity RFA-DA-20-016 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications for a single Coordinating Center to support novel data acquisition strategies, data harmonization, analysis and dissemination activities on emerging and current drug abuse trends across the United States. The Coordinating Center will (1) Maintain a Scientific Advisory Group; (2) Maintain and refine an Early Warning Network composed of local experts on drug abuse data from the selected communities, as well as NIDA-supported community-based researchers, to assist in the ongoing monitoring and interpretation of data; (3) Maintain key community-level indicators for monitoring drug abuse trends and early identification of new synthetic drugs and emerging issues including establishing harmonization of indicators and of presentation and analysis of indicators across the selected communities; (4) Continue to identify and maintain novel sources of data including treatment admissions data, national drug use among adults and youth, law enforcement seizures, and drug poisoning death; (5) Conduct cross-site data analyses from the harmonized Coordinating Center data; (6) Continue to disseminate and identify novel ways to execute dissemination and publication plans of results and findings from the Coordinating Center data, including development and maintenance of a website for disseminating data and findings; (7) Conduct webinars on topics of interest to stakeholders; (8) Conduct on the ground epidemiologic investigations on topics of immediate crisis or need, providing functional feedback to impacted communities towards optimizing current and future response; (9) Provide operational, administrative and logistical support for the Coordinating Center data harmonization and dissemination initiative.

Notice NOT-HL-19-707 from the NIH Guide for Grants and Contracts

Notice NOT-HL-19-706 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-19-042 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), for the development of preclinical porcine-to-nonhuman primate (NHP) models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and/or the induction of immune tolerance; (2) develop effective strategies to improve xenograft survival; and (3) characterize and address the physiological compatibility/limitations of xenografts. The long-term goal of this program is to develop strategies for application of xenotransplantation in the clinic.

Funding Opportunity RFA-AI-19-043 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), for the development of preclinical porcine-to-nonhuman primate (NHP) models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and/or the induction of immune tolerance; (2) develop effective strategies to improve xenograft survival; and (3) characterize and address the physiological compatibility/limitations of xenografts. The long-term goal of this program is to develop strategies for application of xenotransplantation in the clinic.

Funding Opportunity RFA-AG-20-023 from the NIH Guide for Grants and Contracts. This funding opportunity announcement invites applications to plan and initiate collaborative activities that will develop and implement infrastructure appropriate for an Alzheimer's Disease Research Center (P30).